DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains
about
RBP-Jkappa/SHARP recruits CtIP/CtBP corepressors to silence Notch target genesRNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assemblyA divalent FHA/BRCT-binding mechanism couples the MRE11-RAD50-NBS1 complex to damaged chromatinCtIP is required to initiate replication-dependent interstrand crosslink repairAbraxas and RAP80 form a BRCA1 protein complex required for the DNA damage responseDTL/CDT2 is essential for both CDT1 regulation and the early G2/M checkpointPALB2 is an integral component of the BRCA complex required for homologous recombination repairN terminus of CtIP is critical for homologous recombination-mediated double-strand break repairMERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaksMERIT40 facilitates BRCA1 localization and DNA damage repairNBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint controlCCDC98 targets BRCA1 to DNA damage sitesSOSS complexes participate in the maintenance of genomic stabilitySTRUCTURE-FUNCTION OF THE TUMOR SUPPRESSOR BRCA1DNA resection in eukaryotes: deciding how to fix the breakBRCT domains: easy as one, two, threeHuman CtIP promotes DNA end resectionStructural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1BRCA1, a 'complex' protein involved in the maintenance of genomic stabilityCtIP Mutations Cause Seckel and Jawad SyndromesPathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approachStructural and functional analysis of the Crb2-BRCT2 domain reveals distinct roles in checkpoint signaling and DNA damage repairInsights from the crystal structure of the sixth BRCT domain of topoisomerase IIβ binding protein 1Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint controlA CDK-catalysed regulatory phosphorylation for formation of the DNA replication complex Sld2-Dpb11Replication fork instability and the consequences of fork collisions from rereplicationHomologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteinsReplication stress in Mammalian cells and its consequences for mitosisCullin3-KLHL15 ubiquitin ligase mediates CtIP protein turnover to fine-tune DNA-end resectionFactors determining DNA double-strand break repair pathway choice in G2 phaseHuman CtIP mediates cell cycle control of DNA end resection and double strand break repairMinding the gap: the underground functions of BRCA1 and BRCA2 at stalled replication forksBRCA1 targets G2/M cell cycle proteins for ubiquitination and proteasomal degradationChemical genetics reveals a specific requirement for Cdk2 activity in the DNA damage response and identifies Nbs1 as a Cdk2 substrate in human cellsATM-dependent MiR-335 targets CtIP and modulates the DNA damage responseCharacterization of Promiscuous Binding of Phosphor Ligands to Breast-Cancer-Gene 1 (BRCA1) C-Terminal (BRCT): Molecular Dynamics, Free Energy, Entropy and Inhibitor DesignHomologs of breast cancer genes in plantsExpanded roles of the Fanconi anemia pathway in preserving genomic stabilityMechanisms for Structural Variation in the Human GenomeThe MRN-CtIP pathway is required for metaphase chromosome alignment.
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P2860
DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains
description
2004 nî lūn-bûn
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2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年學術文章
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DNA damage-induced cell cycle ...... er of BRCA1 C-terminal domains
@ast
DNA damage-induced cell cycle ...... er of BRCA1 C-terminal domains
@en
DNA damage-induced cell cycle ...... er of BRCA1 C-terminal domains
@en-gb
DNA damage-induced cell cycle ...... er of BRCA1 C-terminal domains
@nl
type
label
DNA damage-induced cell cycle ...... er of BRCA1 C-terminal domains
@ast
DNA damage-induced cell cycle ...... er of BRCA1 C-terminal domains
@en
DNA damage-induced cell cycle ...... er of BRCA1 C-terminal domains
@en-gb
DNA damage-induced cell cycle ...... er of BRCA1 C-terminal domains
@nl
prefLabel
DNA damage-induced cell cycle ...... er of BRCA1 C-terminal domains
@ast
DNA damage-induced cell cycle ...... er of BRCA1 C-terminal domains
@en
DNA damage-induced cell cycle ...... er of BRCA1 C-terminal domains
@en-gb
DNA damage-induced cell cycle ...... er of BRCA1 C-terminal domains
@nl
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DNA damage-induced cell cycle ...... er of BRCA1 C-terminal domains
@en
P2093
Junjie Chen
Xiaochun Yu
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10.1128/MCB.24.21.9478-9486.2004
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2004-11-01T00:00:00Z