BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function
about
Human single-stranded DNA binding proteins are essential for maintaining genomic stabilityScreening for BRCA1, BRCA2, CHEK2, PALB2, BRIP1, RAD50, and CDH1 mutations in high-risk Finnish BRCA1/2-founder mutation-negative breast and/or ovarian cancer individualsStructure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structureBRCA1 interacts with FHL2 and enhances FHL2 transactivation functionAbraxas and RAP80 form a BRCA1 protein complex required for the DNA damage responseRAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sitesDNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domainsThe FANCJ/MutLalpha interaction is required for correction of the cross-link response in FA-J cellsPALB2 is an integral component of the BRCA complex required for homologous recombination repairMERIT40 facilitates BRCA1 localization and DNA damage repairCCDC98 targets BRCA1 to DNA damage sitesPALB2 regulates recombinational repair through chromatin association and oligomerizationInteraction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndromeTIP49b, a regulator of activating transcription factor 2 response to stress and DNA damageConstitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation.Genome-wide comprehensive analysis of human helicasesThe BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutationsStructural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domainsHow the fanconi anemia pathway guards the genomeA sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genomeStructural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1Distinct functions of BRCA1 and BRCA2 in double-strand break repairCancer incidence in relatives of a population-based set of cases of early-onset breast cancer with a known BRCA1 and BRCA2 mutation statusMutation analysis of FANCD2, BRIP1/BACH1, LMO4 and SFN in familial breast cancer.BACH1 Ser919Pro variant and breast cancer risk.Getting Ready for the Dance: FANCJ Irons Out DNA WrinklesInterplay between Fanconi anemia and homologous recombination pathways in genome integrityClose encounters for the first time: Helicase interactions with DNA damageDisease-causing missense mutations in human DNA helicase disordersPhosphopeptide interactions with BRCA1 BRCT domains: More than just a motifMolecular functions and cellular roles of the ChlR1 (DDX11) helicase defective in the rare cohesinopathy Warsaw breakage syndromeEmerging critical roles of Fe-S clusters in DNA replication and repair.BARD1 may be renamed ROW1 because it functions mainly as a REPRESSOR OF WUSCHEL1Structural consequences of a cancer-causing BRCA1-BRCT missense mutationPathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approachMolecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint controlPostreplicative mismatch repair.Chl1p, a DNA helicase-like protein in budding yeast, functions in sister-chromatid cohesion.Chl1 DNA helicase regulates Scc2 deposition specifically during DNA-replication in Saccharomyces cerevisiae.Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3
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P2860
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function
description
2001 nî lūn-bûn
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2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2001 թվականի ապրիլին հրատարակված գիտական հոդված
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2001年の論文
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2001年学术文章
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2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
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name
BACH1, a novel helicase-like p ...... tes to its DNA repair function
@ast
BACH1, a novel helicase-like p ...... tes to its DNA repair function
@en
BACH1, a novel helicase-like p ...... tes to its DNA repair function
@en-gb
BACH1, a novel helicase-like p ...... tes to its DNA repair function
@nl
type
label
BACH1, a novel helicase-like p ...... tes to its DNA repair function
@ast
BACH1, a novel helicase-like p ...... tes to its DNA repair function
@en
BACH1, a novel helicase-like p ...... tes to its DNA repair function
@en-gb
BACH1, a novel helicase-like p ...... tes to its DNA repair function
@nl
prefLabel
BACH1, a novel helicase-like p ...... tes to its DNA repair function
@ast
BACH1, a novel helicase-like p ...... tes to its DNA repair function
@en
BACH1, a novel helicase-like p ...... tes to its DNA repair function
@en-gb
BACH1, a novel helicase-like p ...... tes to its DNA repair function
@nl
P2093
P921
P3181
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P1476
BACH1, a novel helicase-like p ...... tes to its DNA repair function
@en
P2093
D C Wahrer
D M Livingston
S B Cantor
S Grossman
P304
P3181
P356
10.1016/S0092-8674(01)00304-X
P407
P577
2001-04-01T00:00:00Z