Activation of gp130 transduces hypertrophic signal through interaction of scaffolding/docking protein Gab1 with tyrosine phosphatase SHP2 in cardiomyocytes
about
MEK5/ERK5 pathway: the first fifteen yearsMitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale.The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiationRole of protein-tyrosine phosphatase SHP2 in focal adhesion kinase down-regulation during neutrophil cathepsin G-induced cardiomyocytes anoikisThe neurite outgrowth multiadaptor RhoGAP, NOMA-GAP, regulates neurite extension through SHP2 and Cdc42Volume overload induces differential spatiotemporal regulation of myocardial soluble guanylyl cyclase in eccentric hypertrophy and heart failureThe nuclear factor-kappaB-interleukin-6 signalling pathway mediating vascular inflammation.Crosstalk between mitogen-activated protein kinases and mitochondria in cardiac diseases: therapeutic perspectivesPhosphorylation of ERK5 on Thr732 is associated with ERK5 nuclear localization and ERK5-dependent transcription.Interaction of scaffolding adaptor protein Gab1 with tyrosine phosphatase SHP2 negatively regulates IGF-I-dependent myogenic differentiation via the ERK1/2 signaling pathwayGab family proteins are essential for postnatal maintenance of cardiac function via neuregulin-1/ErbB signaling.Mediating ERK 1/2 signaling rescues congenital heart defects in a mouse model of Noonan syndrome.Classic interleukin-6 receptor signaling and interleukin-6 trans-signaling differentially control angiotensin II-dependent hypertension, cardiac signal transducer and activator of transcription-3 activation, and vascular hypertrophy in vivo.Molecular Characterization of Striated Muscle-Specific Gab1 Isoform as a Critical Signal Transducer for Neuregulin-1/ErbB Signaling in Cardiomyocytes.Role of gp130-mediated signalling pathways in the heart and its impact on potential therapeutic aspectsA Cross-Species Study of PI3K Protein-Protein Interactions Reveals the Direct Interaction of P85 and SHP2.Chronic treatment of mice with leukemia inhibitory factor does not cause adverse cardiac remodeling but improves heart function.Crosstalk between signaling pathways of adrenoreceptors and signal transducers and activators of transcription 3 (STAT3) in heart.Differential STAT3 signaling in the heart: Impact of concurrent signals and oxidative stress.LIF and the heart: just another brick in the wall?Mitogen-activated protein kinases in heart development and diseasesCardiac Gab1 deletion leads to dilated cardiomyopathy associated with mitochondrial damage and cardiomyocyte apoptosisNovel role for p21-activated kinase 2 in thrombin-induced monocyte migration.Targeted deletion of BMK1/ERK5 in adult mice perturbs vascular integrity and leads to endothelial failure.Roles of IL-6-gp130 Signaling in Vascular Inflammation.JAK redux: a second look at the regulation and role of JAKs in the heart.gp130-mediated pathway and heart failure.STAT3 and cardiac remodeling.The JAK-STAT pathway in hypertrophic stress signaling and genomic stress response.SOCS3: A novel therapeutic target for cardioprotection.An overview of the inflammatory signalling mechanisms in the myocardium underlying the development of diabetic cardiomyopathy.p42/p44-MAPK and PI3K are sufficient for IL-6 family cytokines/gp130 to signal to hypertrophy and survival in cardiomyocytes in the absence of JAK/STAT activation.Gab adapter proteins as therapeutic targets for hematologic disease.Targeted deletion of the extracellular signal-regulated protein kinase 5 attenuates hypertrophic response and promotes pressure overload-induced apoptosis in the heart.Gab1 Is Modulated by Chronic Hypoxia in Children with Cyanotic Congenital Heart Defect and Its Overexpression Reduces Apoptosis in Rat Neonatal Cardiomyocytes.Novel role of proline-rich nonreceptor tyrosine kinase 2 in vascular wall remodeling after balloon injuryNew insights into the molecular phenotype of eccentric hypertrophy.Shp shape: FAKs about hypertrophy.Gab docking proteins in cardiovascular disease, cancer, and inflammation.TRAF1 Is Critical for DMBA/Solar UVR-Induced Skin Carcinogenesis.
P2860
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P2860
Activation of gp130 transduces hypertrophic signal through interaction of scaffolding/docking protein Gab1 with tyrosine phosphatase SHP2 in cardiomyocytes
description
2003 nî lūn-bûn
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2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
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2003年の論文
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2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Activation of gp130 transduces ...... phatase SHP2 in cardiomyocytes
@ast
Activation of gp130 transduces ...... phatase SHP2 in cardiomyocytes
@en
Activation of gp130 transduces ...... phatase SHP2 in cardiomyocytes
@en-gb
Activation of gp130 transduces ...... phatase SHP2 in cardiomyocytes
@nl
type
label
Activation of gp130 transduces ...... phatase SHP2 in cardiomyocytes
@ast
Activation of gp130 transduces ...... phatase SHP2 in cardiomyocytes
@en
Activation of gp130 transduces ...... phatase SHP2 in cardiomyocytes
@en-gb
Activation of gp130 transduces ...... phatase SHP2 in cardiomyocytes
@nl
prefLabel
Activation of gp130 transduces ...... phatase SHP2 in cardiomyocytes
@ast
Activation of gp130 transduces ...... phatase SHP2 in cardiomyocytes
@en
Activation of gp130 transduces ...... phatase SHP2 in cardiomyocytes
@en-gb
Activation of gp130 transduces ...... phatase SHP2 in cardiomyocytes
@nl
P2093
P1433
P1476
Activation of gp130 transduces ...... phatase SHP2 in cardiomyocytes
@en
P2093
Hisao Hirota
Ichiro Kawase
Kazuo Terai
Keigo Nishida
Keiko Yamauchi-Takihara
Masahiro Izumi
Satoshi Matsuda
Shoko Sugiyama
Toshio Hirano
Yoshikazu Nakaoka
P304
P356
10.1161/01.RES.0000085562.48906.4A
P407
P577
2003-07-10T00:00:00Z