JAK redux: a second look at the regulation and role of JAKs in the heart.
about
Heme controls the regulation of protein tyrosine kinases Jak2 and SrcPivotal Importance of STAT3 in Protecting the Heart from Acute and Chronic Stress: New Advancement and Unresolved IssuesFunctional roles of protein nitration in acute and chronic liver diseasesNovel mutations and their functional and clinical relevance in myeloproliferative neoplasms: JAK2, MPL, TET2, ASXL1, CBL, IDH and IKZF1Acyloxy nitroso compounds inhibit LIF signaling in endothelial cells and cardiac myocytes: evidence that STAT3 signaling is redox-sensitiveNucleophosmin overexpression is associated with poor survival in astrocytoma.Matters of the heart.Elucidating functional context within microarray data by integrated transcription factor-focused gene-interaction and regulatory network analysisInhibition of Janus kinase signaling during controlled mechanical ventilation prevents ventilation-induced diaphragm dysfunctionHuman cytomegalovirus-encoded pUL7 is a novel CEACAM1-like molecule responsible for promotion of angiogenesisPlaying with cardiac "redox switches": the "HNO way" to modulate cardiac function.Phosphorylation of Y372 is critical for Jak2 tyrosine kinase activationInflammation and cardiac outcomeNew frontiers in heart hypertrophy during pregnancy.Depletion of cellular glutathione modulates LIF-induced JAK1-STAT3 signaling in cardiac myocytes.Myocardial Hypertrophic Remodeling and Impaired Left Ventricular Function in Mice with a Cardiac-Specific Deletion of Janus Kinase 2.Differential STAT3 signaling in the heart: Impact of concurrent signals and oxidative stress.High density lipoprotein/sphingosine-1-phosphate-induced cardioprotection: Role of STAT3 as part of the SAFE pathway.Could interferon-gamma be a therapeutic target for treating heart failure?Redox regulation of Janus kinase: The elephant in the room.STAT3 and cardiac remodeling.G-CSF for stem cell therapy in acute myocardial infarction: friend or foe?When are pro-inflammatory cytokines SAFE in heart failure?JAKs go nuclear: emerging role of nuclear JAK1 and JAK2 in gene expression and cell growth.The JAK-STAT pathway in hypertrophic stress signaling and genomic stress response.Progress toward JAK1-selective inhibitors.Upregulation of the large conductance voltage- and Ca2+-activated K+ channels by Janus kinase 2.Functions of cyclophilin A in atherosclerosis.Recombinant Human Erythropoietin Protects Myocardial Cells from Apoptosis via the Janus-Activated Kinase 2/Signal Transducer and Activator of Transcription 5 Pathway in Rats with Epilepsy.Untangle a Broken Heart via Janus Kinase 1.Down-regulation of the epithelial Na⁺ channel ENaC by Janus kinase 2.Down-regulation of the myoinositol transporter SMIT by JAK2.Downregulation of the creatine transporter SLC6A8 by JAK2.Impaired myocardial development resulting in neonatal cardiac hypoplasia alters postnatal growth and stress response in the heart.Impaired JAK2-induced activation of STAT3 in failing human myocytes.
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JAK redux: a second look at the regulation and role of JAKs in the heart.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 28 August 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
JAK redux: a second look at the regulation and role of JAKs in the heart.
@en
JAK redux: a second look at the regulation and role of JAKs in the heart.
@nl
type
label
JAK redux: a second look at the regulation and role of JAKs in the heart.
@en
JAK redux: a second look at the regulation and role of JAKs in the heart.
@nl
prefLabel
JAK redux: a second look at the regulation and role of JAKs in the heart.
@en
JAK redux: a second look at the regulation and role of JAKs in the heart.
@nl
P2860
P1476
JAK redux: a second look at the regulation and role of JAKs in the heart.
@en
P2093
George W Booz
Mazen Kurdi
P2860
P304
P356
10.1152/AJPHEART.00032.2009
P577
2009-08-28T00:00:00Z