Structural basis and specificity of human otubain 1-mediated deubiquitination
about
The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesisOTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitinOTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysisPositive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1Phosphorylation-dependent activity of the deubiquitinase DUBAEvidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1Post-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasionThe otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the EROTUB1 modulates c-IAP1 stability to regulate signalling pathwaysLys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase CezanneMolecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domainsSubstrate specificity of the ubiquitin and Ubl proteasesRegulation of Met1-linked polyubiquitin signalling by the deubiquitinase OTULINUbiquitin in the immune systemDeubiquitinating enzyme regulation of the p53 pathway: A lesson from Otub1Structural Analysis of a Viral Ovarian Tumor Domain Protease from the Crimean-Congo Hemorrhagic Fever Virus in Complex with Covalently Bonded UbiquitinStructural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing proteaseA Role for Intersubunit Interactions in Maintaining SAGA Deubiquitinating Module Structure and ActivityA Strategy for Modulation of Enzymes in the Ubiquitin SystemAn ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chainsOTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme FunctionAssembly, analysis and architecture of atypical ubiquitin chainsThe mechanism of OTUB1-mediated inhibition of ubiquitinationE2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1Ubiquitin chain conformation regulates recognition and activity of interacting proteinsHuman stanniocalcin-1 interacts with nuclear and cytoplasmic proteins and acts as a SUMO E3 ligaseOTUB1 overexpression in mesangial cells is a novel regulator in the pathogenesis of glomerulonephritis through the decrease of DCN levelThe Vps27/Hrs/STAM (VHS) Domain of the Signal-transducing Adaptor Molecule (STAM) Directs Associated Molecule with the SH3 Domain of STAM (AMSH) Specificity to Longer Ubiquitin Chains and Dictates the Position of Cleavage.Identification and developmental expression of Xenopus laevis SUMO proteases.Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.Deubiquitinating enzymes Ubp2 and Ubp15 regulate endocytosis by limiting ubiquitination and degradation of ARTsEhrlichia chaffeensis Tandem Repeat Effector Targets Differentially Influence Infection.Deubiquitinating enzymes as promising drug targets for infectious diseases.Nonenzymatic polymerization of ubiquitin: single-step synthesis and isolation of discrete ubiquitin oligomersLys11- and Lys48-linked ubiquitin chains interact with p97 during endoplasmic-reticulum-associated degradation.SILAC-based quantitative proteomic analysis of human lung cell response to copper oxide nanoparticles.Deubiquitinating enzyme specificity for ubiquitin chain topology profiled by di-ubiquitin activity probesOTUB1 de-ubiquitinating enzyme promotes prostate cancer cell invasion in vitro and tumorigenesis in vivo.OTUB1 promotes metastasis and serves as a marker of poor prognosis in colorectal cancer.
P2860
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P2860
Structural basis and specificity of human otubain 1-mediated deubiquitination
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structural basis and specificity of human otubain 1-mediated deubiquitination
@ast
Structural basis and specificity of human otubain 1-mediated deubiquitination
@en
Structural basis and specificity of human otubain 1-mediated deubiquitination
@en-gb
Structural basis and specificity of human otubain 1-mediated deubiquitination
@nl
type
label
Structural basis and specificity of human otubain 1-mediated deubiquitination
@ast
Structural basis and specificity of human otubain 1-mediated deubiquitination
@en
Structural basis and specificity of human otubain 1-mediated deubiquitination
@en-gb
Structural basis and specificity of human otubain 1-mediated deubiquitination
@nl
prefLabel
Structural basis and specificity of human otubain 1-mediated deubiquitination
@ast
Structural basis and specificity of human otubain 1-mediated deubiquitination
@en
Structural basis and specificity of human otubain 1-mediated deubiquitination
@en-gb
Structural basis and specificity of human otubain 1-mediated deubiquitination
@nl
P2093
P50
P921
P3181
P356
P1433
P1476
Structural basis and specificity of human otubain 1-mediated deubiquitination
@en
P2093
Alexander Iphöfer
Edda Fiebiger
Katalin di Gleria
Masato Akutsu
P304
P3181
P356
10.1042/BJ20081318
P407
P577
2009-03-01T00:00:00Z