Polarised expression of human intestinal N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase (human meprin) alpha and beta subunits in Madin-Darby canine kidney cells
about
Human meprin beta: O-linked glycans in the intervening region of the type I membrane protein protect the C-terminal region from proteolytic cleavage and diminish its secretionMeprins, membrane-bound and secreted astacin metalloproteinasesHeterologously overexpressed, affinity-purified human meprin alpha is functionally active and cleaves components of the basement membrane in vitroStructure of homo- and hetero-oligomeric meprin metalloproteases. Dimers, tetramers, and high molecular mass multimersActivation of human meprin-alpha in a cell culture model of colorectal cancer is triggered by the plasminogen-activating systemSecretion of human meprin from intestinal epithelial cells depends on differential expression of the alpha and beta subunitsProbing the active sites and mechanisms of rat metalloproteases meprin A and BCompartmentalised expression of meprin in small intestinal mucosa: enhanced expression in lamina propria in coeliac disease.The metalloprotease meprinbeta processes E-cadherin and weakens intercellular adhesionMetalloprotease meprin beta in rat kidney: glomerular localization and differential expression in glomerulonephritis.Role of meprins to protect ileal mucosa of Crohn's disease patients from colonization by adherent-invasive E. coliEnhanced activity of meprin-α, a pro-migratory and pro-angiogenic protease, in colorectal cancer.Meprinα transactivates the epidermal growth factor receptor (EGFR) via ligand shedding, thereby enhancing colorectal cancer cell proliferation and migrationMeprin A metalloproteinase and its role in acute kidney injury.A novel 2D-based approach to the discovery of candidate substrates for the metalloendopeptidase meprin.The proamphiregulin cytoplasmic domain is required for basolateral sorting, but is not essential for constitutive or stimulus-induced processing in polarized Madin-Darby canine kidney cells.Human N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase (human meprin): genomic structure of the alpha and beta subunits.N-Benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase beta (human meprinbeta). A 13-amino-acid sequence is required for proteolyticprocessing and subsequent secretion.The carboxyl-terminal tail of kinase splitting membranal proteinase/meprin beta is involved in its intracellular trafficking.Human meprin alpha and beta homo-oligomers: cleavage of basement membrane proteins and sensitivity to metalloprotease inhibitors.Intersubunit and domain interactions of the meprin B metalloproteinase. Disulfide bonds and protein-protein interactions in the MAM and TRAF domains.
P2860
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P2860
Polarised expression of human intestinal N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase (human meprin) alpha and beta subunits in Madin-Darby canine kidney cells
description
1997 nî lūn-bûn
@nan
1997 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Polarised expression of human ...... adin-Darby canine kidney cells
@ast
Polarised expression of human ...... adin-Darby canine kidney cells
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Polarised expression of human ...... adin-Darby canine kidney cells
@en-gb
Polarised expression of human ...... adin-Darby canine kidney cells
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type
label
Polarised expression of human ...... adin-Darby canine kidney cells
@ast
Polarised expression of human ...... adin-Darby canine kidney cells
@en
Polarised expression of human ...... adin-Darby canine kidney cells
@en-gb
Polarised expression of human ...... adin-Darby canine kidney cells
@nl
prefLabel
Polarised expression of human ...... adin-Darby canine kidney cells
@ast
Polarised expression of human ...... adin-Darby canine kidney cells
@en
Polarised expression of human ...... adin-Darby canine kidney cells
@en-gb
Polarised expression of human ...... adin-Darby canine kidney cells
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P2093
P2860
P1433
P1476
Polarised expression of human ...... adin-Darby canine kidney cells
@en
P2093
P2860
P304
P356
10.1111/J.1432-1033.1997.00920.X
P407
P50
P577
1997-08-01T00:00:00Z