RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing
about
Muscle lim protein isoform negatively regulates striated muscle actin dynamics and differentiationA Review of the Giant Protein Titin in Clinical Molecular Diagnostics of CardiomyopathiesMatrin3: connecting gene expression with the nuclear matrixRNA-Binding Proteins: Splicing Factors and DiseaseGlobal impact of RNA splicing on transcriptome remodeling in the heartEvolutionary conservation and expression of human RNA-binding proteins and their role in human genetic diseaseHeart failure with preserved ejection fractionTranscriptome complexity in cardiac development and diseases--an expanding universe between genome and phenomeCyclic stretch of embryonic cardiomyocytes increases proliferation, growth, and expression while repressing Tgf-β signalingMulti-breed and multi-trait co-association analysis of meat tenderness and other meat quality traits in three French beef cattle breeds.Pathophysiological defects and transcriptional profiling in the RBM20-/- rat modelGenetics and disease of ventricular muscle.Clinical and Mechanistic Insights Into the Genetics of CardiomyopathyDefective control of pre-messenger RNA splicing in human diseaseTracks through the genome to physiological eventsSarcomeric protein isoform transitions in cardiac muscle: a journey to heart failureModelling sarcomeric cardiomyopathies in the dish: from human heart samples to iPSC cardiomyocyteshnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and functionNovex-3, the tiny titin of muscle.Genetic epidemiology of titin-truncating variants in the etiology of dilated cardiomyopathy.Genotype-phenotype associations in dilated cardiomyopathy: meta-analysis on more than 8000 individuals.Sequencing of mRNA identifies re-expression of fetal splice variants in cardiac hypertrophy.Heart failure with preserved ejection fraction.The alternative heart: impact of alternative splicing in heart disease.RNA splicing regulated by RBFOX1 is essential for cardiac function in zebrafish.Modeling structural and functional deficiencies of RBM20 familial dilated cardiomyopathy using human induced pluripotent stem cellsTitin-truncating variants affect heart function in disease cohorts and the general population.Aberrant developmental titin splicing and dysregulated sarcomere length in Thymosin β4 knockout mice.Alternative Splicing Signatures in RNA-seq Data: Percent Spliced in (PSI).Next-generation sequencing: from understanding biology to personalized medicine.Titin-mediated control of cardiac myofibrillar function.Experimentally increasing titin compliance in a novel mouse model attenuates the Frank-Starling mechanism but has a beneficial effect on diastole.Transcriptional regulation and alternative splicing cooperate in muscle fiber-type specification in flies and mammals.Hereditary Dilated Cardiomyopathy: Recent Advances in Genetic Diagnostics.Rbm20-deficient cardiogenesis reveals early disruption of RNA processing and sarcomere remodeling establishing a developmental etiology for dilated cardiomyopathy.RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing.Fragile hearts: new insights into translational control in cardiac muscle.Rbm24a and Rbm24b are required for normal somitogenesis.Deletion of the titin N2B region accelerates myofibrillar force development but does not alter relaxation kineticsDelineating RBM20 regulation of alternative splicing in dilated cardiomyopathy
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P2860
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing
description
2012 nî lūn-bûn
@nan
2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing
@ast
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing
@en
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing
@en-gb
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing
@nl
type
label
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing
@ast
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing
@en
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing
@en-gb
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing
@nl
prefLabel
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing
@ast
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing
@en
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing
@en-gb
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing
@nl
P2093
P2860
P50
P921
P3181
P356
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P1476
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing
@en
P2093
Amanda M Parrish
Andreas Perrot
Bastian Spallek
Brenda Gerull
Calum A MacRae
Cemil Özcelik
G William Dec
Henrike Maatz
Herbert Schulz
Kurt W Saupe
P2860
P2888
P304
P3181
P356
10.1038/NM.2693
P407
P50
P577
2012-05-01T00:00:00Z
P5875
P6179
1000224289