Laforin, the most common protein mutated in Lafora disease, regulates autophagy
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)A comprehensive glossary of autophagy-related molecules and processes (2nd edition)Laforin is required for the functional activation of malin in endoplasmic reticulum stress resistance in neuronal cellsAutophagy and neurodegenerationMyocardial autophagic energy stress responses--macroautophagy, mitophagy, and glycophagyAutophagy modulation as a potential therapeutic target for diverse diseasesRole of autophagy in glycogen breakdown and its relevance to chloroquine myopathyLoss of GABAergic cortical neurons underlies the neuropathology of Lafora diseasePTG depletion removes Lafora bodies and rescues the fatal epilepsy of Lafora diseaseLacritin and other autophagy associated proteins in ocular surface health.Long-term exposure to 835 MHz RF-EMF induces hyperactivity, autophagy and demyelination in the cortical neurons of mice.Abnormal glycogen chain length pattern, not hyperphosphorylation, is critical in Lafora disease.Protein degradation and quality control in cells from laforin and malin knockout mice.A PTG variant contributes to a milder phenotype in Lafora diseaseGenetic depletion of the malin E3 ubiquitin ligase in mice leads to lafora bodies and the accumulation of insoluble laforinIncreased oxidative stress and impaired antioxidant response in Lafora disease.Impaired autophagy in Lafora diseaseDimerization of the glucan phosphatase laforin requires the participation of cysteine 329.Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers.PTEN increases autophagy and inhibits the ubiquitin-proteasome pathway in glioma cells independently of its lipid phosphatase activityAutophagy induction halts axonal degeneration in a mouse model of X-adrenoleukodystrophy.VMP1-deficient Chlamydomonas exhibits severely aberrant cell morphology and disrupted cytokinesisMalin regulates Wnt signaling pathway through degradation of dishevelled2Laforin, a protein with many faces: glucan phosphatase, adapter protein, et alii.Muscle glycogen remodeling and glycogen phosphate metabolism following exhaustive exercise of wild type and laforin knockout mice.Impaired GAPDH-induced mitophagy contributes to the pathology of Huntington's disease.Loss of protein targeting to glycogen sensitizes human hepatocellular carcinoma cells towards glucose deprivation mediated oxidative stress and cell deathDeciphering the role of malin in the lafora progressive myoclonus epilepsyDeleterious effects of neuronal accumulation of glycogen in flies and miceNeuronatin-mediated aberrant calcium signaling and endoplasmic reticulum stress underlie neuropathology in Lafora diseaseAge-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevityGlycogen and its metabolism: some new developments and old themes.Activation of serum/glucocorticoid-induced kinase 1 (SGK1) underlies increased glycogen levels, mTOR activation, and autophagy defects in Lafora disease.Everolimus does not prevent Lafora body formation in murine Lafora disease.Laforin-malin complex degrades polyglucosan bodies in concert with glycogen debranching enzyme and brain isoform glycogen phosphorylaseProtein misfolding disorders and macroautophagy.Autophagy and misfolded proteins in neurodegeneration.Autophagy in the cellular energetic balance.Neuroprotection in metabolism-based therapy.Autophagy: for better or for worse.
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P2860
Laforin, the most common protein mutated in Lafora disease, regulates autophagy
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Laforin, the most common protein mutated in Lafora disease, regulates autophagy
@ast
Laforin, the most common protein mutated in Lafora disease, regulates autophagy
@en
Laforin, the most common protein mutated in Lafora disease, regulates autophagy
@en-gb
Laforin, the most common protein mutated in Lafora disease, regulates autophagy
@nl
type
label
Laforin, the most common protein mutated in Lafora disease, regulates autophagy
@ast
Laforin, the most common protein mutated in Lafora disease, regulates autophagy
@en
Laforin, the most common protein mutated in Lafora disease, regulates autophagy
@en-gb
Laforin, the most common protein mutated in Lafora disease, regulates autophagy
@nl
prefLabel
Laforin, the most common protein mutated in Lafora disease, regulates autophagy
@ast
Laforin, the most common protein mutated in Lafora disease, regulates autophagy
@en
Laforin, the most common protein mutated in Lafora disease, regulates autophagy
@en-gb
Laforin, the most common protein mutated in Lafora disease, regulates autophagy
@nl
P2093
P2860
P50
P921
P356
P1476
Laforin, the most common protein mutated in Lafora disease, regulates autophagy
@en
P2093
Carmen Aguado
David C Rubinsztein
Erwin Knecht
Olga Criado
P275
P2860
P304
P356
10.1093/HMG/DDQ190
P407
P50
P5008
P577
2010-07-15T00:00:00Z