Isolation of the human PEX12 gene, mutated in group 3 of the peroxisome biogenesis disorders
about
Expression of PEX11beta mediates peroxisome proliferation in the absence of extracellular stimuliMutation in PEX16 is causal in the peroxisome-deficient Zellweger syndrome of complementation group D.Peroxisome synthesis in the absence of preexisting peroxisomesA novel human DNA-binding protein with sequence similarity to a subfamily of redox proteins which is able to repress RNA-polymerase-III-driven transcription of the Alu-family retroposons in vitroPEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein importPEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesisIdentification and characterization of HAOX1, HAOX2, and HAOX3, three human peroxisomal 2-hydroxy acid oxidasesMolecular anatomy of the peroxin Pex12p: ring finger domain is essential for Pex12p function and interacts with the peroxisome-targeting signal type 1-receptor Pex5p and a ring peroxin, Pex10pMultiple distinct targeting signals in integral peroxisomal membrane proteinsThe dynamin-like GTPase DLP1 is essential for peroxisome division and is recruited to peroxisomes in part by PEX11Alternative splicing suggests extended function of PEX26 in peroxisome biogenesis.PEX19 is a predominantly cytosolic chaperone and import receptor for class 1 peroxisomal membrane proteinsCloning and characterization of the gene encoding the human peroxisomal assembly protein Pex3pPEX3 functions as a PEX19 docking factor in the import of class I peroxisomal membrane proteinsIdentification of PAHX, a Refsum disease geneIdentification of PEX10, the gene defective in complementation group 7 of the peroxisome-biogenesis disordersPEX5 binds the PTS1 independently of Hsp70 and the peroxin PEX12PEX12 encodes an integral membrane protein of peroxisomesClofibrate-inducible, 28-kDa peroxisomal integral membrane protein is encoded by PEX11PEX12, the pathogenic gene of group III Zellweger syndrome: cDNA cloning by functional complementation on a CHO cell mutant, patient analysis, and characterization of PEX12pPeroxisome targeting signal type 1 (PTS1) receptor is involved in import of both PTS1 and PTS2: studies with PEX5-defective CHO cell mutants.PEX11alpha is required for peroxisome proliferation in response to 4-phenylbutyrate but is dispensable for peroxisome proliferator-activated receptor alpha-mediated peroxisome proliferationPhenotype-genotype relationships in complementation group 3 of the peroxisome-biogenesis disordersPEX13 is mutated in complementation group 13 of the peroxisome-biogenesis disorders.The peroxin pex3p initiates membrane assembly in peroxisome biogenesisHuman PEX1 cloned by functional complementation on a CHO cell mutant is responsible for peroxisome-deficient Zellweger syndrome of complementation group IDisruption of a PEX1-PEX6 interaction is the most common cause of the neurologic disorders Zellweger syndrome, neonatal adrenoleukodystrophy, and infantile Refsum diseasePeroxisomes in brain development and functionDisruption of the Saccharomyces cerevisiae FAT1 gene decreases very long-chain fatty acyl-CoA synthetase activity and elevates intracellular very long-chain fatty acid concentrations.The peroxin Pex14p. cDNA cloning by functional complementation on a Chinese hamster ovary cell mutant, characterization, and functional analysisNovel mutations in the PEX12 gene of patients with a peroxisome biogenesis disorderAdrenoleukodystrophy and related disorders.Characterization of peroxisomal Pex5p from rat liver. Pex5p in the Pex5p-Pex14p membrane complex is a transmembrane protein.Genomic structure and identification of 11 novel mutations of the PEX6 (peroxisome assembly factor-2) gene in patients with peroxisome biogenesis disorders.Chondrodysplasia punctata and maternal systemic lupus erythematosus.Peroxisome biogenesis and peroxisome biogenesis disorders.Genetic and molecular bases of peroxisome biogenesis disorders.Plasma very long chain fatty acids in 3,000 peroxisome disease patients and 29,000 controls.Identification of an inhibitory budding signal that blocks the release of HIV particles and exosome/microvesicle proteins.Characterization of glycosomal RING finger proteins of trypanosomatids.
P2860
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P2860
Isolation of the human PEX12 gene, mutated in group 3 of the peroxisome biogenesis disorders
description
1997 nî lūn-bûn
@nan
1997 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Isolation of the human PEX12 g ...... eroxisome biogenesis disorders
@ast
Isolation of the human PEX12 g ...... eroxisome biogenesis disorders
@en
Isolation of the human PEX12 g ...... eroxisome biogenesis disorders
@en-gb
Isolation of the human PEX12 g ...... eroxisome biogenesis disorders
@nl
type
label
Isolation of the human PEX12 g ...... eroxisome biogenesis disorders
@ast
Isolation of the human PEX12 g ...... eroxisome biogenesis disorders
@en
Isolation of the human PEX12 g ...... eroxisome biogenesis disorders
@en-gb
Isolation of the human PEX12 g ...... eroxisome biogenesis disorders
@nl
prefLabel
Isolation of the human PEX12 g ...... eroxisome biogenesis disorders
@ast
Isolation of the human PEX12 g ...... eroxisome biogenesis disorders
@en
Isolation of the human PEX12 g ...... eroxisome biogenesis disorders
@en-gb
Isolation of the human PEX12 g ...... eroxisome biogenesis disorders
@nl
P2093
P2860
P356
P1433
P1476
Isolation of the human PEX12 g ...... eroxisome biogenesis disorders
@en
P2093
P2860
P2888
P356
10.1038/NG0497-385
P407
P577
1997-04-01T00:00:00Z
P5875
P6179
1011887701