The human protein kinase HIPK2 phosphorylates and downregulates the methyl-binding transcription factor ZBTB4
about
Homeodomain-interacting protein kinase 2 plays an important role in normal terminal erythroid differentiationHomeodomain-Interacting Protein Kinase-2: A Critical Regulator of the DNA Damage Response and the EpigenomeMBD4 cooperates with DNMT1 to mediate methyl-DNA repression and protects mammalian cells from oxidative stress.Synthesis and properties of a selective inhibitor of homeodomain-interacting protein kinase 2 (HIPK2).Emerging role of DYRK family protein kinases as regulators of protein stability in cell cycle control.Homeodomain-interacting protein kinase-2 stabilizes p27(kip1) by its phosphorylation at serine 10 and contributes to cell motility.HIPK2 modification code for cell death and survival.Homeodomain-interacting protein kinase 2-dependent repression of myogenic differentiation is relieved by its caspase-mediated cleavage.HIPK2 kinase activity depends on cis-autophosphorylation of its activation loop.An RNA interference screen identifies druggable regulators of MeCP2 stability.Variants regulating ZBTB4 are associated with age-at-onset of Alzheimer's disease.Homeodomain-interacting protein kinase 2 regulates DNA damage response through interacting with heterochromatin protein 1γ.HIPK2 phosphorylates ΔNp63α and promotes its degradation in response to DNA damage.[Research progress and application of the homeodomain-interacting protein kinase-2].
P2860
Q24303477-AAF3BAC6-49A1-4D61-99FF-1D0D36F143C5Q28073422-5A488A36-1A88-4520-8CFD-D63406A3592DQ34000404-17F86A18-DBF2-4E4F-A340-9A8586B97B9EQ35106800-706BE8ED-1711-4829-9695-273A4D1979BAQ38037304-2A190B42-C310-4DA0-A738-64B4091D43FCQ38673048-1ED11CB8-A0A1-4C4A-A5A2-E65274A90CE7Q38866672-C9E3996F-DDA2-44B9-859C-9FA8B02D99B7Q39160093-D8FC6380-694C-44A2-9B19-B44A7FC002ABQ39273658-623605DE-D88E-44D6-87BF-25C81BF27564Q46022392-2073100C-4E5C-495F-B672-10B128802502Q48013134-4DE1F9D3-8422-4A8F-93D6-1DFACFC1FF69Q53025500-C4D69003-BC63-4A26-9507-94C4E23A0528Q54588191-4A72C102-B08D-41C3-85DA-72EE526CDD7BQ55447436-525FA117-1843-4E88-91FD-EFA9FF1A12E8
P2860
The human protein kinase HIPK2 phosphorylates and downregulates the methyl-binding transcription factor ZBTB4
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The human protein kinase HIPK2 ...... ing transcription factor ZBTB4
@ast
The human protein kinase HIPK2 ...... ing transcription factor ZBTB4
@en
The human protein kinase HIPK2 ...... ing transcription factor ZBTB4
@en-gb
The human protein kinase HIPK2 ...... ing transcription factor ZBTB4
@nl
type
label
The human protein kinase HIPK2 ...... ing transcription factor ZBTB4
@ast
The human protein kinase HIPK2 ...... ing transcription factor ZBTB4
@en
The human protein kinase HIPK2 ...... ing transcription factor ZBTB4
@en-gb
The human protein kinase HIPK2 ...... ing transcription factor ZBTB4
@nl
prefLabel
The human protein kinase HIPK2 ...... ing transcription factor ZBTB4
@ast
The human protein kinase HIPK2 ...... ing transcription factor ZBTB4
@en
The human protein kinase HIPK2 ...... ing transcription factor ZBTB4
@en-gb
The human protein kinase HIPK2 ...... ing transcription factor ZBTB4
@nl
P2093
P2860
P50
P921
P3181
P356
P1433
P1476
The human protein kinase HIPK2 ...... ing transcription factor ZBTB4
@en
P2093
M L Schmitz
R Pérez-Torrado
V Devignot
P2860
P2888
P304
P3181
P356
10.1038/ONC.2009.109
P407
P577
2009-05-18T00:00:00Z
P5875
P6179
1051754073