PCOLCE2 encodes a functional procollagen C-proteinase enhancer (PCPE2) that is a collagen-binding protein differing in distribution of expression and post-translational modification from the previously described PCPE1
about
Extended interaction network of procollagen C-proteinase enhancer-1 in the extracellular matrixWhat does procollagen C-endopeptidase enhancer protein 2 have to do with HDL-cholesteryl ester uptake? Or how I learned to stop worrying and love reverse cholesterol transport?NMR structure of the netrin-like domain (NTR) of human type I procollagen C-proteinase enhancer defines structural consensus of NTR domains and assesses potential proteinase inhibitory activity and ligand bindingBone morphogenetic protein-1/Tolloid-like proteinases process dentin matrix protein-1Genome-wide profile of pleural mesothelioma versus parietal and visceral pleura: the emerging gene portrait of the mesothelioma phenotypeNegative regulation of bone formation by the transmembrane Wnt antagonist Kremen-2.Gene expression profiling of cholangiocarcinoma-derived fibroblast reveals alterations related to tumor progression and indicates periostin as a poor prognostic marker.Procollagen C proteinase enhancer 1 genes are important determinants of the mechanical properties and geometry of bone and the ultrastructure of connective tissues.Identification of the minimal domain structure of bone morphogenetic protein-1 (BMP-1) for chordinase activity: chordinase activity is not enhanced by procollagen C-proteinase enhancer-1 (PCPE-1).Mammalian tolloid-like 1 binds procollagen C-proteinase enhancer protein 1 and differs from bone morphogenetic protein 1 in the functional roles of homologous protein domains.Insights into how CUB domains can exert specific functions while sharing a common fold: conserved and specific features of the CUB1 domain contribute to the molecular basis of procollagen C-proteinase enhancer-1 activity.COL1 C-propeptide cleavage site mutations cause high bone mass osteogenesis imperfecta.A genome-wide association study of saturated, mono- and polyunsaturated red blood cell fatty acids in the Framingham Heart Offspring StudyUse of Bmp1/Tll1 doubly homozygous null mice and proteomics to identify and validate in vivo substrates of bone morphogenetic protein 1/tolloid-like metalloproteinasesCubbing in proapolipoprotein maturation.Disruption of the murine procollagen C-proteinase enhancer 2 gene causes accumulation of pro-apoA-I and increased HDL levels.Identification of CTLA2A, DEFB29, WFDC15B, SERPINA1F and MUP19 as Novel Tissue-Specific Secretory Factors in Mouse.Metalloproteinases in Drosophila to humans that are central players in developmental processes.Procollagen C-endopeptidase Enhancer Protein 2 (PCPE2) Reduces Atherosclerosis in Mice by Enhancing Scavenger Receptor Class B1 (SR-BI)-mediated High-density Lipoprotein (HDL)-Cholesteryl Ester UptakeGenome-wide transcriptome analysis of hypothalamus in rats with inherited stress-induced arterial hypertension.Exome sequencing in one family with gastric- and rectal cancer.Effects of the absence of procollagen C-endopeptidase enhancer-2 on myocardial collagen accumulation in chronic pressure overloadDiverse biological functions of extracellular collagen processing enzymesCellular mechanisms of tissue fibrosis. 2. Contributory pathways leading to myocardial fibrosis: moving beyond collagen expression.Procollagen C-proteinase enhancer grasps the stalk of the C-propeptide trimer to boost collagen precursor maturation.The bone morphogenetic protein 1/Tolloid-like metalloproteinasesDifferences in the degree of cerulein-induced chronic pancreatitis in C57BL/6 mouse substrains lead to new insights in identification of potential risk factors in the development of chronic pancreatitis.Comparative proteomic analysis of extracellular matrix proteins secreted by hypertrophic scar with normal skin fibroblastsDefining cell-type specificity at the transcriptional level in human diseasePeriodontal Ehlers-Danlos Syndrome Is Caused by Mutations in C1R and C1S, which Encode Subcomponents C1r and C1s of Complement.Characterization of gene expression profiles in HBV-related liver fibrosis patients and identification of ITGBL1 as a key regulator of fibrogenesis.Myocardial fibroblast-matrix interactions and potential therapeutic targetsProcollagen C-proteinase enhancer stimulates procollagen processing by binding to the C-propeptide region only.Binding of procollagen C-proteinase enhancer-1 (PCPE-1) to heparin/heparan sulfate: properties and role in PCPE-1 interaction with cells.Strong cooperativity and loose geometry between CUB domains are the basis for procollagen c-proteinase enhancer activity.Regulation of apoAI processing by procollagen C-proteinase enhancer-2 and bone morphogenetic protein-1.Dentin sialophosphoprotein (DSPP) is cleaved into its two natural dentin matrix products by three isoforms of bone morphogenetic protein-1 (BMP1).Substrate-specific modulation of a multisubstrate proteinase. C-terminal processing of fibrillar procollagens is the only BMP-1-dependent activity to be enhanced by PCPE-1.Matrix and cell phenotype differences in Dupuytren's disease.Sizzled is unique among secreted frizzled-related proteins for its ability to specifically inhibit bone morphogenetic protein-1 (BMP-1)/tolloid-like proteinases.
P2860
Q24338239-A3DB7E93-1212-4916-90E5-2ABEA5AB5691Q26821862-5B2EFEA9-CEC8-4F1C-9A75-5CD11B7EE8A0Q27640875-56B6AC8A-E455-4CC1-8616-D7AC72B7E1FDQ28212436-847997FB-C9B0-4FE4-95A3-18F411E9A4B0Q28475905-5020652A-E98C-481E-B1BF-1CF9ACE6B990Q33570529-D7D47720-6BCA-41D2-AFF3-01E5B56021D8Q33738887-FD46329A-BC72-4B56-BC36-659D1B4F03B7Q34233484-B944481F-1439-4B86-9F05-77DDBB630CECQ34409686-9DEC878F-9A13-4C69-927C-C532EDE0A659Q34498298-B76C7BB2-3699-470F-9953-29F5482310BDQ34620832-647D4281-4B5F-401A-8034-919F258E5E19Q35012002-6D70E137-E609-43CB-A3EA-35B64F7525DEQ35118206-C01EF7EE-7CF0-4C06-B6D0-C18CA8AFE4EDQ35150332-30897F1F-FAD2-432C-B01C-348C1EE5D12AQ35380046-DEEB8CAB-4543-4FDB-B34F-66E180BE83C2Q35380116-E6D1D3DF-AE8B-4BFC-9DED-0AE46D0AC670Q35577047-59B1CC67-E331-4AA9-9367-0F3076735392Q35604976-9521217B-2A63-40BF-8F74-B934CC7F34A4Q35860634-A4117692-8BC3-4FA7-B5FD-3E2756AA939AQ35907627-2CDF8340-4C17-4772-AE45-537B2B53F6C0Q35922790-D6254D1B-6BB3-4E01-9B27-0BB234AF460CQ36115526-4AC2C722-9CAB-4AD1-A631-2872C7B69F5AQ36259191-EA37E50A-F684-4BA1-8EE4-03D619328F5DQ36699619-BA4AF1A4-E7C0-4388-8A7E-DA85537EF4A3Q36781961-D4B2E767-8F9D-444F-BE96-1D13A6F674E5Q36846125-C831273A-72F6-4361-BC70-490B59B8344DQ37149048-3F8DE6CF-B870-4531-8F68-8E881948D8B2Q37233489-0B88C5C5-C685-4601-ABDB-221328D05861Q37272437-F9F63DB5-7E60-42D7-8EA9-5CAD99085672Q37396896-7D9AE7AC-751D-4D77-8BE5-4358929158DFQ37681790-C666D9A4-AA8F-4C9A-80F5-2BA4E9192D93Q37734270-D4ACE105-B0C0-46ED-89B8-50E22B122CB6Q39469580-6F7524FF-E5E8-4A4C-BE89-4A96A01E9699Q39664721-C849AFF6-577F-4BC6-BBBC-46484C80C343Q39791753-3AE70D13-2D8A-45C2-8A4C-F9F73CEA8AD1Q39880462-4E6022C1-177B-445D-B8EA-B5C78F58A5DEQ40307101-1165C831-0DDB-4FDF-8666-30770BAA47F3Q40434283-4DE2C7E4-A886-4008-BB5E-37754031F162Q42480775-2769AA0E-EB78-4B5B-AC5E-09D672E7B403Q42532115-DA1597DC-8BB7-4930-B533-8334BE83C979
P2860
PCOLCE2 encodes a functional procollagen C-proteinase enhancer (PCPE2) that is a collagen-binding protein differing in distribution of expression and post-translational modification from the previously described PCPE1
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
PCOLCE2 encodes a functional p ...... the previously described PCPE1
@ast
PCOLCE2 encodes a functional p ...... the previously described PCPE1
@en
PCOLCE2 encodes a functional p ...... the previously described PCPE1
@en-gb
PCOLCE2 encodes a functional p ...... the previously described PCPE1
@nl
type
label
PCOLCE2 encodes a functional p ...... the previously described PCPE1
@ast
PCOLCE2 encodes a functional p ...... the previously described PCPE1
@en
PCOLCE2 encodes a functional p ...... the previously described PCPE1
@en-gb
PCOLCE2 encodes a functional p ...... the previously described PCPE1
@nl
prefLabel
PCOLCE2 encodes a functional p ...... the previously described PCPE1
@ast
PCOLCE2 encodes a functional p ...... the previously described PCPE1
@en
PCOLCE2 encodes a functional p ...... the previously described PCPE1
@en-gb
PCOLCE2 encodes a functional p ...... the previously described PCPE1
@nl
P2093
P2860
P921
P3181
P356
P1476
PCOLCE2 encodes a functional p ...... the previously described PCPE1
@en
P2093
Barry M Steiglitz
Daniel S Greenspan
Douglas R Keene
P2860
P304
P3181
P356
10.1074/JBC.M209891200
P407
P577
2002-12-20T00:00:00Z