Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency
about
Spatiotemporal regulation of chloride intracellular channel protein CLIC4 by RhoA.Essential role for Galpha13 in endothelial cells during embryonic developmentSphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF.Interaction of Galpha 12 and Galpha 13 with the cytoplasmic domain of cadherin provides a mechanism for beta -catenin releaseEdg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturationIdentification and characterization of a novel lysophosphatidic acid receptor, p2y5/LPA6BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiationG Protein-Coupled Receptors in CancerCdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.Glycoprotein-340 binds surfactant protein-A (SP-A) and stimulates alveolar macrophage migration in an SP-A-independent mannerG proteins G12 and G13 control the dynamic turnover of growth factor-induced dorsal rufflesIdentification of Galpha13 as one of the G-proteins that couple to human platelet thromboxane A2 receptorsThe first inner loop of endothelin receptor type B is necessary for specific coupling to Galpha 13Disruption of G-protein γ5 subtype causes embryonic lethality in miceNormal hematopoiesis and inflammatory responses despite discrete signaling defects in Galpha15 knockout miceUnsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular developmentActivation of G12/G13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse plateletsRegulation of cAMP responses by the G12/13 pathway converges on adenylyl cyclase VIIInteraction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathwaysZebrafish G protein gamma2 is required for VEGF signaling during angiogenesis.A new approach to producing functional G alpha subunits yields the activated and deactivated structures of G alpha(12/13) proteinsS1pr2/Gα13 signaling controls myocardial migration by regulating endoderm convergence.Gene profiling techniques and their application in angiogenesis and vascular development.Differential cerebral cortex transcriptomes of baboon neonates consuming moderate and high docosahexaenoic acid formulas.More pieces of the platelet activation puzzle slide into placeExtra-nuclear signaling of progesterone receptor to breast cancer cell movement and invasion through the actin cytoskeleton.Minimally perturbing a gene regulatory network to avoid a disease phenotype: the glioma network as a test case.Structure and function of heterotrimeric G protein-regulated Rho guanine nucleotide exchange factors.Identification and characterization of regulator of G protein signaling 4 (RGS4) as a novel inhibitor of tubulogenesis: RGS4 inhibits mitogen-activated protein kinases and vascular endothelial growth factor signaling.Galpha13 regulates MEF2-dependent gene transcription in endothelial cells: role in angiogenesis.S1P3 receptor-induced reorganization of epithelial tight junctions compromises lung barrier integrity and is potentiated by TNF.Tec/Bmx non-receptor tyrosine kinases are involved in regulation of Rho and serum response factor by Galpha12/13Heterotrimeric G protein signaling outside the realm of seven transmembrane domain receptorsIn vivo functions of heterotrimeric G-proteins: studies in Galpha-deficient mice.Identification and molecular characterization of the G alpha12-Rho guanine nucleotide exchange factor pathway in Caenorhabditis elegansThe Galpha13-Rho signaling axis is required for SDF-1-induced migration through CXCR4.The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis.Heterotrimeric G-protein alpha-12 (Gα12) subunit promotes oral cancer metastasis.Sphingosine-1-phosphate signaling in vasculogenesis and angiogenesis.
P2860
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P2860
Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency
@ast
Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency
@en
Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency
@en-gb
Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency
@nl
type
label
Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency
@ast
Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency
@en
Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency
@en-gb
Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency
@nl
prefLabel
Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency
@ast
Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency
@en
Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency
@en-gb
Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency
@nl
P2093
P3181
P1433
P1476
Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency
@en
P2093
P3181
P356
10.1126/SCIENCE.275.5299.533
P407
P577
1997-01-24T00:00:00Z