S1P3 receptor-induced reorganization of epithelial tight junctions compromises lung barrier integrity and is potentiated by TNF.
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Role of Sphingolipids in the Pathobiology of Lung InflammationLysophospholipids and their receptors in the central nervous systemSUMOylation attenuates sensitivity toward hypoxia- or desferroxamine-induced injury by modulating adaptive responses in salivary epithelial cellsInhibition of sphingosine kinase-2 suppresses inflammation and attenuates graft injury after liver transplantation in ratsSphingosine-1-phosphate receptor 1 agonism attenuates lung ischemia-reperfusion injury.Chronic sphingosine 1-phosphate 1 receptor activation attenuates early-stage diabetic nephropathy independent of lymphocytes.Stereochemistry-activity relationship of orally active tetralin S1P agonist prodrugs.Asymmetric synthesis of conformationally constrained fingolimod analogues--discovery of an orally active sphingosine 1-phosphate receptor type-1 agonist and receptor type-3 antagonist.Divergent roles of sphingosine kinases in kidney ischemia-reperfusion injury.Sphingosine-1-phosphate receptors: biology and therapeutic potential in kidney diseaseBiological roles of lysophospholipid receptors revealed by genetic null mice: an update.Activated tumor cell integrin αvβ3 cooperates with platelets to promote extravasation and metastasis from the blood stream.Novel GPCR screening approach: indirect identification of S1P receptor agonists in antagonist screening using a calcium assay.Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesionsPharmacological pre- and post-conditioning with the sphingosine-1-phosphate receptor modulator FTY720 after myocardial ischaemia-reperfusionDifferential effects of sphingosine 1-phosphate receptors on airway and vascular barrier function in the murine lung.Distinct roles of sphingosine kinases 1 and 2 in human mast-cell functions.Prolonged exposure to sphingosine 1-phosphate receptor-1 agonists exacerbates vascular leak, fibrosis, and mortality after lung injury.Multiple-dose tolerability, pharmacokinetics, and pharmacodynamics of ponesimod, an S1P1 receptor modulator: favorable impact of dose up-titration."Inside-out" signaling of sphingosine-1-phosphate: therapeutic targets.Pharmacological relevance and potential of sphingosine 1-phosphate in the vascular system.Sphingosine kinase-2 inhibition improves mitochondrial function and survival after hepatic ischemia-reperfusion.Involvement of ceramide in cell death responses in the pulmonary circulation.Sphingosine-1-phosphate in allergic responses, asthma and anaphylaxis.Hyperoxia disrupts pulmonary epithelial barrier in newborn rats via the deterioration of occludin and ZO-1Bile acids and sphingosine-1-phosphate receptor 2 in hepatic lipid metabolism.The role of sphingosine-1-phosphate in breast cancer tumor-induced lymphangiogenesis.Pulmonary endothelial cell barrier enhancement by novel FTY720 analogs: methoxy-FTY720, fluoro-FTY720, and β-glucuronide-FTY720.Sphingolipids and membrane biology as determined from genetic models.Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-δ.Cytosolic phospholipase A2alpha activation induced by S1P is mediated by the S1P3 receptor in lung epithelial cells.Balance of S1P1 and S1P2 signaling regulates peripheral microvascular permeability in rat cremaster muscle vasculature.Biomechanics of liquid-epithelium interactions in pulmonary airways.Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice.Activated protein C in sepsis: the promise of nonanticoagulant activated protein C.Synthetic analogs of FTY720 [2-amino-2-(2-[4-octylphenyl]ethyl)-1,3-propanediol] differentially regulate pulmonary vascular permeability in vivo and in vitro.Lyase to live by: sphingosine phosphate lyase as a therapeutic target.Activation of the lung S1P(1) receptor reduces allergen-induced plasma leakage in miceSphingolipids in inflammation: pathological implications and potential therapeutic targets.The Dual Role of TNF in Pulmonary Edema.
P2860
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P2860
S1P3 receptor-induced reorganization of epithelial tight junctions compromises lung barrier integrity and is potentiated by TNF.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
S1P3 receptor-induced reorgani ...... ity and is potentiated by TNF.
@ast
S1P3 receptor-induced reorgani ...... ity and is potentiated by TNF.
@en
type
label
S1P3 receptor-induced reorgani ...... ity and is potentiated by TNF.
@ast
S1P3 receptor-induced reorgani ...... ity and is potentiated by TNF.
@en
prefLabel
S1P3 receptor-induced reorgani ...... ity and is potentiated by TNF.
@ast
S1P3 receptor-induced reorgani ...... ity and is potentiated by TNF.
@en
P2093
P2860
P356
P1476
S1P3 receptor-induced reorgani ...... ity and is potentiated by TNF.
@en
P2093
Euijung Jo
Hugh Rosen
Jerold Chun
M Germana Sanna
Malcolm R Wood
William B Kiosses
Yasuhiro Gon
P2860
P304
P356
10.1073/PNAS.0501997102
P407
P577
2005-06-20T00:00:00Z