Bone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells
about
ALK1 signaling regulates early postnatal lymphatic vessel developmentTargeting BMP signalling in cardiovascular disease and anaemiaPotential roles of BMP9 in liver fibrosisSpecificity and Structure of a High Affinity Activin Receptor-like Kinase 1 (ALK1) Signaling ComplexBMP-9 induced endothelial cell tubule formation and inhibition of migration involves Smad1 driven endothelin-1 production.Beyond CDR-grafting: Structure-guided humanization of framework and CDR regions of an anti-myostatin antibody.Novel mutations in BMPR2, ACVRL1 and KCNA5 genes and hemodynamic parameters in patients with pulmonary arterial hypertension.Molecular pathways: can activin-like kinase pathway inhibition enhance the limited efficacy of VEGF inhibitors?Fine mapping of the hereditary haemorrhagic telangiectasia (HHT)3 locus on chromosome 5 excludes VE-Cadherin-2, Sprouty4 and other interval genes.BMP9 (bone morphogenetic protein 9) induces NGF as an autocrine/paracrine cholinergic trophic factor in developing basal forebrain neurons.TGFbeta/BMP type I receptors ALK1 and ALK2 are essential for BMP9-induced osteogenic signaling in mesenchymal stem cells.Structural and functional insights into endoglin ligand recognition and binding.BMP type II receptors have redundant roles in the regulation of hepatic hepcidin gene expression and iron metabolismRegulation of bone morphogenetic protein 9 (BMP9) by redox-dependent proteolysis.Endoglin requirement for BMP9 signaling in endothelial cells reveals new mechanism of action for selective anti-endoglin antibodies.Structural Basis of the Human Endoglin-BMP9 Interaction: Insights into BMP Signaling and HHT1Directional next-generation RNA sequencing and examination of premature termination codon mutations in endoglin/hereditary haemorrhagic telangiectasiaDynamic analysis of BMP-responsive smad activity in live zebrafish embryosALK1 as an emerging target for antiangiogenic therapy of cancerEndothelial depletion of Acvrl1 in mice leads to arteriovenous malformations associated with reduced endoglin expression.Altered MicroRNA processing in heritable pulmonary arterial hypertension: an important role for Smad-8Mutation in BMPR2 Promoter: A 'Second Hit' for Manifestation of Pulmonary Arterial Hypertension?Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension.Novel homozygous BMP9 nonsense mutation causes pulmonary arterial hypertension: a case report.RNA Sequencing Analysis Detection of a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension.Bone Morphogenetic Protein-9 Enhances Osteogenic Differentiation of Human Periodontal Ligament Stem Cells via the JNK Pathway.FGF, Insulin, and SMAD Signaling Cooperate for Avian Primordial Germ Cell Self-RenewalBMP9 regulates endoglin-dependent chemokine responses in endothelial cells.Mouse and human strategies identify PTPN14 as a modifier of angiogenesis and hereditary haemorrhagic telangiectasia.The promise of recombinant BMP ligands and other approaches targeting BMPR-II in the treatment of pulmonary arterial hypertensionBMP signaling in mesenchymal stem cell differentiation and bone formation.BMP receptor 1A regulates development of hypothalamic circuits critical for feeding behavior.BMP9 signaling in stem cell differentiation and osteogenesis.In Pulmonary Arterial Hypertension, Reduced BMPR2 Promotes Endothelial-to-Mesenchymal Transition via HMGA1 and Its Target SlugFunctional redundancy of type II BMP receptor and type IIB activin receptor in BMP2-induced osteoblast differentiationContext-dependent signaling defines roles of BMP9 and BMP10 in embryonic and postnatal development.Correction of nonsense BMPR2 and SMAD9 mutations by ataluren in pulmonary arterial hypertension.Bone morphogenetic protein 9 overexpression reduces osteosarcoma cell migration and invasion.Id proteins are critical downstream effectors of BMP signaling in human pulmonary arterial smooth muscle cells.Glucocorticoids recruit Tgfbr3 and Smad1 to shift transforming growth factor-β signaling from the Tgfbr1/Smad2/3 axis to the Acvrl1/Smad1 axis in lung fibroblasts.
P2860
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P2860
Bone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Bone morphogenetic protein (BM ...... onary artery endothelial cells
@ast
Bone morphogenetic protein (BM ...... onary artery endothelial cells
@en
Bone morphogenetic protein (BM ...... onary artery endothelial cells
@en-gb
Bone morphogenetic protein (BM ...... onary artery endothelial cells
@nl
type
label
Bone morphogenetic protein (BM ...... onary artery endothelial cells
@ast
Bone morphogenetic protein (BM ...... onary artery endothelial cells
@en
Bone morphogenetic protein (BM ...... onary artery endothelial cells
@en-gb
Bone morphogenetic protein (BM ...... onary artery endothelial cells
@nl
prefLabel
Bone morphogenetic protein (BM ...... onary artery endothelial cells
@ast
Bone morphogenetic protein (BM ...... onary artery endothelial cells
@en
Bone morphogenetic protein (BM ...... onary artery endothelial cells
@en-gb
Bone morphogenetic protein (BM ...... onary artery endothelial cells
@nl
P2860
P921
P356
P1476
Bone morphogenetic protein (BM ...... onary artery endothelial cells
@en
P2093
Paul D Upton
Rachel J Davies
P2860
P304
P356
10.1074/JBC.M109.002881
P407
P577
2009-06-05T00:00:00Z