SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma
about
Cancer as a metabolic diseaseSIRT5-mediated lysine desuccinylation impacts diverse metabolic pathwaysSuccinate dehydrogenase 5 (SDH5) regulates glycogen synthase kinase 3β-β-catenin-mediated lung cancer metastasisSdhE is a conserved protein required for flavinylation of succinate dehydrogenase in bacteriaLithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cellsMitochondrial metabolic remodeling in response to genetic and environmental perturbationsCurrent perspectives between metabolic syndrome and cancerMitochondrial Redox Signaling and Tumor ProgressionHuman Metabolic Enzymes Deficiency: A Genetic Mutation Based ApproachPheochromocytomas and Paragangliomas: Clinical and Genetic ApproachesDecoding Warburg's hypothesis: tumor-related mutations in the mitochondrial respiratory chainSuccinate Dehydrogenase Loss in Familial Paraganglioma: Biochemistry, Genetics, and Epigenetics15 YEARS OF PARAGANGLIOMA: Clinical manifestations of paraganglioma syndromes types 1-5Tumors of the neural crest: Common themes in development and cancerPhysiological consequences of complex II inhibition for aging, disease, and the mKATP channelGenetically-defined metabolic reprogramming in cancerPower(2): the power of yeast genetics applied to the powerhouse of the cellThe flavoproteome of the yeast Saccharomyces cerevisiaeAn update on the genetics of pheochromocytomaPheochromocytoma: implications in tumorigenesis and the actual managementSolution NMR Structure of Yeast Succinate Dehydrogenase Flavinylation Factor Sdh5 Reveals a Putative Sdh1 Binding SiteIdentification of a protein mediating respiratory supercomplex stabilityThe LYR factors SDHAF1 and SDHAF3 mediate maturation of the iron-sulfur subunit of succinate dehydrogenaseA stress-responsive system for mitochondrial protein degradationSDHAF4 promotes mitochondrial succinate dehydrogenase activity and prevents neurodegeneration.Instability of succinate dehydrogenase in SDHD polymorphism connects reactive oxygen species production to nuclear and mitochondrial genomic mutations in yeastFlavinylation and assembly of succinate dehydrogenase are dependent on the C-terminal tail of the flavoprotein subunit.Oncometabolites: Unconventional triggers of oncogenic signalling cascadesExome sequencing identifies MAX mutations as a cause of hereditary pheochromocytomaConnecting molecular pathways to hereditary cancer risk syndromesNoninvasive diagnostics of mitochondrial disorders in isolated lymphocytes with high resolution respirometryA 14.7 kDa protein from Francisella tularensis subsp. novicida (named FTN_1133), involved in the response to oxidative stress induced by organic peroxides, is not endowed with thiol-dependent peroxidase activityProton-associated sucrose transport of mammalian solute carrier family 45: an analysis in Saccharomyces cerevisiaeRobust succinic acid production from crude glycerol using engineered Yarrowia lipolyticaRole of mitochondrial dysfunction in cancer progressionMitochondrial dynamics associated with oxygen-glucose deprivation in rat primary neuronal culturesStructural and biochemical analyses reveal insights into covalent flavinylation of the Escherichia coli Complex II homolog quinol:fumarate reductase.High-throughput screening for growth inhibitors using a yeast model of familial paraganglioma.Realizing the promise of cancer predisposition genes.CRISPR-Cas gene-editing reveals RsmA and RsmC act through FlhDC to repress the SdhE flavinylation factor and control motility and prodigiosin production in Serratia.
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P2860
SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma
description
2009 nî lūn-bûn
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2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
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2009年の論文
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2009年論文
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2009年論文
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2009年論文
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2009年論文
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2009年論文
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2009年论文
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SDH5, a gene required for flav ...... e, is mutated in paraganglioma
@ast
SDH5, a gene required for flav ...... e, is mutated in paraganglioma
@en
SDH5, a gene required for flav ...... e, is mutated in paraganglioma
@en-gb
SDH5, a gene required for flav ...... e, is mutated in paraganglioma
@nl
type
label
SDH5, a gene required for flav ...... e, is mutated in paraganglioma
@ast
SDH5, a gene required for flav ...... e, is mutated in paraganglioma
@en
SDH5, a gene required for flav ...... e, is mutated in paraganglioma
@en-gb
SDH5, a gene required for flav ...... e, is mutated in paraganglioma
@nl
prefLabel
SDH5, a gene required for flav ...... e, is mutated in paraganglioma
@ast
SDH5, a gene required for flav ...... e, is mutated in paraganglioma
@en
SDH5, a gene required for flav ...... e, is mutated in paraganglioma
@en-gb
SDH5, a gene required for flav ...... e, is mutated in paraganglioma
@nl
P2093
P2860
P50
P3181
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P1433
P1476
SDH5, a gene required for flav ...... e, is mutated in paraganglioma
@en
P2093
Brandon G Bentz
Cor W R J Cremers
Dennis R Winge
Hannie Kremer
Henricus Kunst
Huai-Xiang Hao
Jared Rutter
Jean-Pierre Bayley
Joshua D Schiffman
Margit Schraders
P2860
P304
P3181
P356
10.1126/SCIENCE.1175689
P407
P577
2009-08-28T00:00:00Z