RAP, a specialized chaperone, prevents ligand-induced ER retention and degradation of LDL receptor-related endocytic receptors - Wikidata - awgldk - TriplyDB

RAP, a specialized chaperone, prevents ligand-induced ER retention and degradation of LDL receptor-related endocytic receptors

RAP, a specialized chaperone, prevents ligand-induced ER retention and degradation of LDL receptor-related endocytic receptors

http://www.wikidata.org/entity/Q24317297

about

The generation and function of soluble apoE receptors in the CNS Low-density-lipoprotein-receptor-related protein (LRP) interacts with a GTP-binding protein Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand binding.Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotype Defective forebrain development in mice lacking gp330/megalin.The solution structure of the N-terminal domain of alpha2-macroglobulin receptor-associated protein The structure of receptor-associated protein (RAP)Mutations in LRPAP1 are associated with severe myopia in humans Mechanism of the facilitation of PC2 maturation by 7B2: involvement in ProPC2 transport and activation but not folding LRAD3, a novel low-density lipoprotein receptor family member that modulates amyloid precursor protein trafficking Structural basis of transcobalamin recognition by human CD320 receptor Generation of a Potent Low Density Lipoprotein Receptor-related Protein 1 (LRP1) Antagonist by Engineering a Stable Form of the Receptor-associated Protein (RAP) D3 Domain Lactoferrin--a novel bone growth factor Mechanisms regulating plasminogen activators in transformed retinal ganglion cells.High Plasma Lipid Levels Reduce Efficacy of Adenovirus-Mediated Gene Therapy LRP1 is a receptor for Clostridium perfringens TpeL toxin indicating a two-receptor model of clostridial glycosylating toxins Mutational screening of SLC39A5, LEPREL1 and LRPAP1 in a cohort of 187 high myopia patients.Low-Density Lipoprotein Receptor-Related Protein-1 Signaling in Angiogenesis.Endoplasmic reticulum localization of the low density lipoprotein receptor mediates presecretory degradation of apolipoprotein B TNFα-induced apoptosis enabled by CCN1/CYR61: pathways of reactive oxygen species generation and cytochrome c release.Oxidative modification to LDL receptor-related protein 1 in hippocampus from subjects with Alzheimer disease: implications for Aβ accumulation in AD brain Premature ligand-receptor interaction during biosynthesis limits the production of growth factor midkine and its receptor LDL receptor-related protein 1 Network topologies and convergent aetiologies arising from deletions and duplications observed in individuals with autism.Receptor-associated protein blocks internalization and cytotoxicity of myeloma light chain in cultured human proximal tubular cells.Clearance of amyloid-beta peptide across the blood-brain barrier: implication for therapies in Alzheimer's disease.Cancer and embryo expression protein 65 promotes cancer cell growth and metastasis.The unfolded protein response is a major mechanism by which LRP1 regulates Schwann cell survival after injury.The endocytic receptor protein LRP also mediates neuronal calcium signaling via N-methyl-D-aspartate receptors Neurovascular defects and faulty amyloid-β vascular clearance in Alzheimer's disease Factor VIII Interacts with the Endocytic Receptor Low-density Lipoprotein Receptor-related Protein 1 via an Extended Surface Comprising "Hot-Spot" Lysine Residues.Deficiency of receptor-associated protein attenuates angiotensin II-induced atherosclerosis in hypercholesterolemic mice without influencing abdominal aortic aneurysms Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells.Expression and regulation of apolipoprotein E receptors in the cells of the central nervous system in culture: A review.Tissue and urokinase plasminogen activators instigate the degeneration of retinal ganglion cells in a mouse model of glaucoma.Low-density Lipoprotein Receptor-related Proteins in a Novel Mechanism of Axon Guidance and Peripheral Nerve Regeneration LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies The role of the cell surface LRP and soluble LRP in blood-brain barrier Abeta clearance in Alzheimer's disease.Receptor-associated protein (RAP) has two high-affinity binding sites for the low-density lipoprotein receptor-related protein (LRP): consequences for the chaperone functions of RAP.Hepatic apo E expression is required for remnant lipoprotein clearance in the absence of the low density lipoprotein receptor.

P2860

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P2860

RAP, a specialized chaperone, prevents ligand-induced ER retention and degradation of LDL receptor-related endocytic receptors

http://www.wikidata.org/entity/Q24317297

description

1996 nî lūn-bûn

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1996 թուականի Յունիսին հրատարակուած գիտական յօդուած

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1996 թվականի հունիսին հրատարակված գիտական հոդված

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1996年の論文

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1996年論文

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1996年論文

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1996年論文

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J.1460-2075.1996.TB00623.X

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The EMBO Journal

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RAP, a specialized chaperone, ...... or-related endocytic receptors

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Braun JR

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Hammer RE

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Herz J

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Horton J

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Rohlmann A

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Willnow TE

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P2860

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor

The 39-kDa receptor-associated protein regulates ligand binding by the very low density lipoprotein receptor

7B2 is a neuroendocrine chaperone that transiently interacts with prohormone convertase PC2 in the secretory pathway

Proteolytic processing of the 600 kd low density lipoprotein receptor-related protein (LRP) occurs in a trans-Golgi compartment

39 kDa receptor-associated protein is an ER resident protein and molecular chaperone for LDL receptor-related protein

Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease

39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor

Inhibition of hepatic chylomicron remnant uptake by gene transfer of a receptor antagonist

Functional expression of low density lipoprotein receptor-related protein is controlled by receptor-associated protein in vivo

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2632-2639

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molecular chaperones

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450198

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