Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy
about
The ubiquilin gene family: evolutionary patterns and functional insightsGenome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WACUbiquilin 1 interacts with Orai1 to regulate calcium mobilizationUbiquilin4 is an adaptor protein that recruits Ubiquilin1 to the autophagy machineryC9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal traffickingSVIP induces localization of p97/VCP to the plasma and lysosomal membranes and regulates autophagyImpaired Autophagy and Defective Mitochondrial Function: Converging Paths on the Road to Motor Neuron DegenerationUltrastructural studies of ALS mitochondria connect altered function and permeability with defects of mitophagy and mitochondriogenesisThe different roles of selective autophagic protein degradation in mammalian cellsAutophagosome dynamics in neurodegeneration at a glanceSelective autophagy mediated by autophagic adapter proteinsBioanalysis of eukaryotic organellesIdentification of genetic modifiers of TDP-43 neurotoxicity in DrosophilaDifferential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 speciesReduced body weight gain in ubiquilin-1 transgenic mice is associated with increased expression of energy-sensing proteinsLC3, an autophagosome marker, is expressed on oligodendrocytes in Nasu-Hakola disease brains.Protein kinase C-alpha suppresses autophagy and induces neural tube defects via miR-129-2 in diabetic pregnancy.Chaperone-mediated autophagy at a glance.Establishment of a novel fluorescence-based method to evaluate chaperone-mediated autophagy in a single neuron.Protein aggregation and degradation mechanisms in neurodegenerative diseasesThe emerging roles of microRNAs in the pathogenesis of frontotemporal dementia-amyotrophic lateral sclerosis (FTD-ALS) spectrum disordersUbiquilin 2 is not associated with tau pathologySignature changes in ubiquilin expression in the R6/2 mouse model of Huntington's disease.Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies.Regulation of autophagy by neuropathological protein TDP-43.Defective Proteasome Delivery of Polyubiquitinated Proteins by Ubiquilin-2 Proteins Containing ALS Mutations.Ubiquilin 1 Promotes IFN-γ-Induced Xenophagy of Mycobacterium tuberculosisUbiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1.Crosstalk Between Macroautophagy and Chaperone-Mediated Autophagy: Implications for the Treatment of Neurological Diseases.Differential recruitment of UBQLN2 to nuclear inclusions in the polyglutamine diseases HD and SCA3.Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion.Ubiquitin receptors and protein quality controlPathogenic Ubqln2 gains toxic properties to induce neuron death.Ubiquilin-mediated Small Molecule Inhibition of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling.CD47 signaling pathways controlling cellular differentiation and responses to stress.The TREX1 C-terminal region controls cellular localization through ubiquitination.Port-to-port delivery: Mobilization of toxic sphingolipids via extracellular vesicles.iLIR database: A web resource for LIR motif-containing proteins in eukaryotes.Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS-FTD-linked UBQLN2 mutations.Ubiquilin-1 overexpression increases the lifespan and delays accumulation of Huntingtin aggregates in the R6/2 mouse model of Huntington's disease.
P2860
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P248
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P2860
Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy
@ast
Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy
@en
Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy
@en-gb
Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy
@nl
type
label
Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy
@ast
Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy
@en
Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy
@en-gb
Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy
@nl
prefLabel
Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy
@ast
Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy
@en
Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy
@en-gb
Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy
@nl
P2093
P2860
P921
P3181
P356
P1476
Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy
@en
P2093
Cara Rothenberg
Corrine M Peterhoff
Deepa Srinivasan
Janet Ugolino
Mervyn J Monteiro
Ralph A Nixon
Shengyun Fang
P2860
P304
P3181
P356
10.1093/HMG/DDQ231
P407
P5008
P577
2010-08-15T00:00:00Z