about
Phosphoinositide 3-kinase: friend and foe in cardiovascular diseaseNovel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli CellsAdipose tissue insulin resistance due to loss of PI3K p110α leads to decreased energy expenditure and obesitySCF, BDNF, and Gas6 are regulators of growth plate chondrocyte proliferation and differentiation.Phosphoinositide 3-kinaseγ controls the intracellular localization of CpG to limit DNA-PKcs-dependent IL-10 production in macrophagesIdentification of components of the host type IA phosphoinositide 3-kinase pathway that promote internalization of Listeria monocytogenes.Evolutionary history of phosphatidylinositol- 3-kinases: ancestral origin in eukaryotes and complex duplication patterns.Identification and classification of small molecule kinases: insights into substrate recognition and specificity.ADP signaling in vascular endothelial cells: ADP-dependent activation of the endothelial isoform of nitric-oxide synthase requires the expression but not the kinase activity of AMP-activated protein kinase.Classes of phosphoinositide 3-kinases at a glance.Phosphoinositide 3-kinase γ inhibits cardiac GSK-3 independently of Akt.Regulation of the actin cytoskeleton-plasma membrane interplay by phosphoinositides.Specific PI3K isoform modulation in heart failure: lessons from transgenic mice.Nuclear phosphoinositides and their roles in cell biology and disease.Multiple roles for the p85α isoform in the regulation and function of PI3K signalling and receptor trafficking.Therapeutic applications of PI3K inhibitors in cardiovascular diseases.Molecules in medicine mini-review: isoforms of PI3K in biology and disease.The secret life of kinases: functions beyond catalysisScaffolding Function of PI3Kgamma Emerges from Enzyme's Shadow.Integrating cardiac PIP3 and cAMP signaling through a PKA anchoring function of p110γ.Role of Host Type IA Phosphoinositide 3-Kinase Pathway Components in Invasin-Mediated Internalization of Yersinia enterocoliticaGenetic ablation of PI3Kγ results in defective IL-17RA signalling in T lymphocytes and increased IL-17 levels.PI3K class IB controls the cell cycle checkpoint promoting cell proliferation in hepatocellular carcinoma.Phosphoinositide-3 kinase gamma activity contributes to sepsis and organ damage by altering neutrophil recruitment.
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Twice upon a time: PI3K's secret double life exposed
@ast
Twice upon a time: PI3K's secret double life exposed
@en
Twice upon a time: PI3K's secret double life exposed
@en-gb
Twice upon a time: PI3K's secret double life exposed
@nl
type
label
Twice upon a time: PI3K's secret double life exposed
@ast
Twice upon a time: PI3K's secret double life exposed
@en
Twice upon a time: PI3K's secret double life exposed
@en-gb
Twice upon a time: PI3K's secret double life exposed
@nl
prefLabel
Twice upon a time: PI3K's secret double life exposed
@ast
Twice upon a time: PI3K's secret double life exposed
@en
Twice upon a time: PI3K's secret double life exposed
@en-gb
Twice upon a time: PI3K's secret double life exposed
@nl
P50
P1476
Twice upon a time: PI3K's secret double life exposed
@en
P2093
Alessia Perino
Laura Braccini
P304
P356
10.1016/J.TIBS.2009.02.003
P407
P577
2009-04-17T00:00:00Z