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Epidermal growth factor receptor (EGFR) signaling requires a specific endoplasmic reticulum thioredoxin for the post-translational control of receptor presentation to the cell surfaceNon-canonical signaling mode of the epidermal growth factor receptor familyInducing Oncoprotein Degradation to Improve Targeted Cancer TherapyTen things you should know about protein kinases: IUPHAR Review 14The enzymes of human diphosphoinositol polyphosphate metabolismNovel Reporter for Faithful Monitoring of ERK2 Dynamics in Living Cells and Model Organisms.Plasmodium berghei MAPK1 displays differential and dynamic subcellular localizations during liver stage developmentFluorophore Labeled Kinase Detects Ligands That Bind within the MAPK Insert of p38α KinaseActive site profiling reveals coupling between domains in SRC-family kinasesNetwork-level effects of kinase inhibitors modulate TNF-α-induced apoptosis in the intestinal epitheliumDecoding the Interactions Regulating the Active State Mechanics of Eukaryotic Protein KinasesDivergent modulation of Src-family kinase regulatory interactions with ATP-competitive inhibitors.Dual-specificity MAP kinase phosphatases (MKPs): shaping the outcome of MAP kinase signalling.Induced protein degradation: an emerging drug discovery paradigm.Biological targets and mechanisms of action of natural products from marine cyanobacteria.Endorepellin affects angiogenesis by antagonizing diverse vascular endothelial growth factor receptor 2 (VEGFR2)-evoked signaling pathways: transcriptional repression of hypoxia-inducible factor 1α and VEGFA and concurrent inhibition of nuclear factRational design of a secreted enzymatically inactive mutant of extracellular superoxide dismutase.LKB1 controls human bronchial epithelial morphogenesis through p114RhoGEF-dependent RhoA activationErbB4 reduces synaptic GABAA currents independent of its receptor tyrosine kinase activity.ERK5 kinase activity is dispensable for cellular immune response and proliferation.Classes of phosphoinositide 3-kinases at a glance.Preconditioning of bone marrow mesenchymal stem cells with hydrogen sulfide improves their therapeutic potential.Beyond 'furballs' and 'dumpling soups' - towards a molecular architecture of signaling complexes and networks.It takes two to tango--signalling by dimeric Raf kinases.EGFR targeted therapies and radiation: Optimizing efficacy by appropriate drug scheduling and patient selection.Allosteric modulators of MEK1: drug design and discovery.Choline kinase-α protein and phosphatidylcholine but not phosphocholine are required for breast cancer cell survival.Targeting ABL-IRE1α Signaling Spares ER-Stressed Pancreatic β Cells to Reverse Autoimmune Diabetes.Advancement of mass spectrometry-based proteomics technologies to explore triple negative breast cancer.Scaffolding Function of PI3Kgamma Emerges from Enzyme's Shadow.Addressing the Functional Determinants of FAK during Ciliogenesis in Multiciliated Cells.Non-kinase targets of protein kinase inhibitors.Novel approaches for targeting kinases: allosteric inhibition, allosteric activation and pseudokinases.Ubiquitin enzymes in the regulation of immune responses.A non-catalytic role of choline kinase alpha is important in promoting cancer cell survival.Regulation of Catalytic and Non-catalytic Functions of the Drosophila Ste20 Kinase Slik by Activation Segment PhosphorylationStructure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38α MAPK.A positive feedback loop between Gli1 and tyrosine kinase Hck amplifies shh signaling activities in medulloblastomaDual Roles of Fer Kinase Are Required for Proper Hematopoiesis and Vascular Endothelium Organization during Zebrafish Development.Neuroprotective Effects of Hydrogen Sulfide Against Early Brain Injury and Secondary Cognitive Deficits Following Subarachnoid Hemorrhage.
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The secret life of kinases: functions beyond catalysis
@en
The secret life of kinases: functions beyond catalysis.
@nl
type
label
The secret life of kinases: functions beyond catalysis
@en
The secret life of kinases: functions beyond catalysis.
@nl
prefLabel
The secret life of kinases: functions beyond catalysis
@en
The secret life of kinases: functions beyond catalysis.
@nl
P2860
P356
P1476
The secret life of kinases: functions beyond catalysis
@en
P2093
David Romano
Natalia Volinsky
P2860
P2888
P356
10.1186/1478-811X-9-23
P577
2011-10-28T00:00:00Z
P6179
1026866275