Overexpression of IRS2 in isolated pancreatic islets causes proliferation and protects human beta-cells from hyperglycemia-induced apoptosis
about
Identification of a WD40 repeat-containing isoform of PHIP as a novel regulator of beta-cell growth and survivalDevelopment of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adaptersDifferential effects of protein kinase B/Akt isoforms on glucose homeostasis and islet mass.CREB mediates the insulinotropic and anti-apoptotic effects of GLP-1 signaling in adult mouse β-cells.The CaMK4/CREB/IRS-2 cascade stimulates proliferation and inhibits apoptosis of β-cellsInhibition of Raf-1 alters multiple downstream pathways to induce pancreatic beta-cell apoptosis.MiR-126 Suppresses the Glucose-Stimulated Proliferation via IRS-2 in INS-1 β Cells.Development of beta-amyloid-induced neurodegeneration in Alzheimer's disease and novel neuroprotective strategies.On the role of IRS2 in the regulation of functional beta-cell mass.Beta cells in type 2 diabetes - a crucial contribution to pathogenesis.Irs2 inactivation suppresses tumor progression in Pten+/- mice.The cytotoxic role of intermittent high glucose on apoptosis and cell viability in pancreatic beta cells.From signal transduction to signal interpretation: an alternative model for the molecular function of insulin receptor substrates.Wnt3a regulates proliferation, apoptosis and function of pancreatic NIT-1 beta cells via activation of IRS2/PI3K signaling.Intermittent high glucose enhances apoptosis in INS-1 cellsSelective deletion of Pten in pancreatic beta cells leads to increased islet mass and resistance to STZ-induced diabetes.Elimination of negative feedback control mechanisms along the insulin signaling pathway improves beta-cell function under stress.IL-4 and IL-13 Receptor Signaling From 4PS to Insulin Receptor Substrate 2: There and Back Again, a Historical View.Increased IRS2 mRNA Expression in SGA Neonates: PCR Analysis of Insulin/IGF Signaling in Cord Blood.
P2860
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P2860
Overexpression of IRS2 in isolated pancreatic islets causes proliferation and protects human beta-cells from hyperglycemia-induced apoptosis
description
2005 nî lūn-bûn
@nan
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Overexpression of IRS2 in isol ...... yperglycemia-induced apoptosis
@ast
Overexpression of IRS2 in isol ...... yperglycemia-induced apoptosis
@en
Overexpression of IRS2 in isol ...... yperglycemia-induced apoptosis
@en-gb
Overexpression of IRS2 in isol ...... yperglycemia-induced apoptosis
@nl
type
label
Overexpression of IRS2 in isol ...... yperglycemia-induced apoptosis
@ast
Overexpression of IRS2 in isol ...... yperglycemia-induced apoptosis
@en
Overexpression of IRS2 in isol ...... yperglycemia-induced apoptosis
@en-gb
Overexpression of IRS2 in isol ...... yperglycemia-induced apoptosis
@nl
prefLabel
Overexpression of IRS2 in isol ...... yperglycemia-induced apoptosis
@ast
Overexpression of IRS2 in isol ...... yperglycemia-induced apoptosis
@en
Overexpression of IRS2 in isol ...... yperglycemia-induced apoptosis
@en-gb
Overexpression of IRS2 in isol ...... yperglycemia-induced apoptosis
@nl
P2093
P921
P1476
Overexpression of IRS2 in isol ...... yperglycemia-induced apoptosis
@en
P2093
Zuellig RA
P356
10.1016/J.YEXCR.2004.09.011
P407
P577
2005-02-01T00:00:00Z