CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination
about
ATM-Dependent Phosphorylation of All Three Members of the MRN Complex: From Sensor to AdaptorFunctional Role of NBS1 in Radiation Damage Response and Translesion DNA SynthesisThe intersection between DNA damage response and cell death pathwaysCdk1-dependent regulation of the Mre11 complex couples DNA repair pathways to cell cycle progressionPhosphorylation of EXO1 by CDKs 1 and 2 regulates DNA end resection and repair pathway choice.Regulatory functional territory of PLK-1 and their substrates beyond mitosis.Productive replication of human papillomavirus 31 requires DNA repair factor Nbs1.The 9-1-1 checkpoint clamp stimulates DNA resection by Dna2-Sgs1 and Exo1.Pathway choice in DNA double strand break repair: observations of a balancing act.XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair.APC/C(Cdh1) controls CtIP stability during the cell cycle and in response to DNA damage.Regulators of homologous recombination repair as novel targets for cancer treatment.Sumoylation influences DNA break repair partly by increasing the solubility of a conserved end resection protein.Biochemical mechanism of DSB end resection and its regulation.LAMMER kinase contributes to genome stability in Ustilago maydis.NBS1 and multiple regulations of DNA damage response.NBS1 Phosphorylation Status Dictates Repair Choice of Dysfunctional Telomeres.Alpha thalassemia/mental retardation syndrome X-linked gene product ATRX is required for proper replication restart and cellular resistance to replication stress.Enrichment of Cdk1-cyclins at DNA double-strand breaks stimulates Fun30 phosphorylation and DNA end resection.Controlling DNA-end resection: a new task for CDKs.Sharpening the ends for repair: mechanisms and regulation of DNA resection.Distinct functions of human cohesin-SA1 and cohesin-SA2 in double-strand break repairAssociation between the NBS1 Glu185Gln polymorphism and lung cancer risk: a systemic review and meta-analysis.DNA double-strand break repair as determinant of cellular radiosensitivity to killing and target in radiation therapy.Cell cycle regulation of homologous recombination in Saccharomyces cerevisiae.Augmented HR Repair Mediates Acquired Temozolomide Resistance in Glioblastoma.Cyclin D1 promotes BRCA2-Rad51 interaction by restricting cyclin A/B-dependent BRCA2 phosphorylation.ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1.CDK1 inhibition targets the p53-NOXA-MCL1 axis, selectively kills embryonic stem cells, and prevents teratoma formation.RAD50 phosphorylation promotes ATR downstream signaling and DNA restart following replication stress.The control of DNA repair by the cell cycle.Phosphorylated (pT371)TRF1 is recruited to sites of DNA damage to facilitate homologous recombination and checkpoint activation.Prophase I: Preparing Chromosomes for Segregation in the Developing Oocyte.Cell cycle-dependent control of homologous recombination.Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.H4K20me2 distinguishes pre-replicative from post-replicative chromatin to appropriately direct DNA repair pathway choice by 53BP1-RIF1-MAD2L2.DNA-damage-induced degradation of EXO1 exonuclease limits DNA end resection to ensure accurate DNA repair.Mitotic and Meiotic Functions for the SUMOylation Pathway in the Caenorhabditis elegans Germline.Deoxyribonucleic Acid Damage and Repair: Capitalizing on Our Understanding of the Mechanisms of Maintaining Genomic Integrity for Therapeutic Purposes.PARK2 orchestrates cyclins to avoid cancer.
P2860
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P2860
CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
CDK targeting of NBS1 promotes ...... t and homologous recombination
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CDK targeting of NBS1 promotes ...... t and homologous recombination
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CDK targeting of NBS1 promotes ...... t and homologous recombination
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CDK targeting of NBS1 promotes ...... t and homologous recombination
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type
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CDK targeting of NBS1 promotes ...... t and homologous recombination
@ast
CDK targeting of NBS1 promotes ...... t and homologous recombination
@en
CDK targeting of NBS1 promotes ...... t and homologous recombination
@en-gb
CDK targeting of NBS1 promotes ...... t and homologous recombination
@nl
prefLabel
CDK targeting of NBS1 promotes ...... t and homologous recombination
@ast
CDK targeting of NBS1 promotes ...... t and homologous recombination
@en
CDK targeting of NBS1 promotes ...... t and homologous recombination
@en-gb
CDK targeting of NBS1 promotes ...... t and homologous recombination
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P2093
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P50
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CDK targeting of NBS1 promotes ...... t and homologous recombination
@en
P2093
Jacob Falck
Julia Coates
Martin Mistrik
P2860
P3181
P356
10.1038/EMBOR.2012.58
P407
P577
2012-06-01T00:00:00Z