Cloning, mapping and expression of PEBP2 alpha C, a third gene encoding the mammalian Runt domain
about
A novel transcript encoding an N-terminally truncated AML1/PEBP2 alphaB protein interferes with transactivation and blocks granulocytic differentiation of 32Dcl3 myeloid cellsA WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator.A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasiaA mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemiaPhysical interaction of the activator protein-1 factors c-Fos and c-Jun with Cbfa1 for collagenase-3 promoter activationRUNX3 has an oncogenic role in head and neck cancerMaturational disturbance of chondrocytes in Cbfa1-deficient miceRunx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehogHematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA binding subunit of the transcription factor, polyomavirus enhancer binding protein 2/core binding factorIdentification of the regions involved in DNA binding by the mouse PEBP2alpha protein.Absence of fetal liver hematopoiesis in mice deficient in transcriptional coactivator core binding factor beta.The common retroviral insertion locus Dsi1 maps 30 kilobases upstream of the P1 promoter of the murine Runx3/Cbfa3/Aml2 geneTwo domains unique to osteoblast-specific transcription factor Osf2/Cbfa1 contribute to its transactivation function and its inability to heterodimerize with CbfbetaMolecular basis of tissue-specific gene expression mediated by the runt domain transcription factor PEBP2/CBF.Core-binding factor influences the disease specificity of Moloney murine leukemia virusAuto-inhibition of Ets-1 is counteracted by DNA binding cooperativity with core-binding factor alpha2.RUNX3 is involved in caspase-3-dependent apoptosis induced by a combination of 5-aza-CdR and TSA in leukaemia cell lines.Expression pattern, regulation, and biological role of runt domain transcription factor, run, in Caenorhabditis elegansRUNX3 suppresses migration, invasion and angiogenesis of human renal cell carcinoma.The RUNX3 tumor suppressor upregulates Bim in gastric epithelial cells undergoing transforming growth factor beta-induced apoptosis.Runx transcription factors repress human and murine c-Myc expression in a DNA-binding and C-terminally dependent manner.Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis.A Cbfa1-dependent genetic pathway controls bone formation beyond embryonic development.Runx3 controls growth and differentiation of gastric epithelial cells in mammals.CCAAT enhancer-binding protein (C/EBP) and AML1 (CBF alpha2) synergistically activate the macrophage colony-stimulating factor receptor promoter.The extracellular signal-regulated kinase pathway phosphorylates AML1, an acute myeloid leukemia gene product, and potentially regulates its transactivation ability.Functional analysis of RUNX2 mutations in Japanese patients with cleidocranial dysplasia demonstrates novel genotype-phenotype correlations.Downregulation of the RUNX3 gene by promoter hypermethylation and hemizygous deletion in breast cancer.Role of RUNX3 in suppressing metastasis and angiogenesis of human prostate cancer.Expression of the human acute myeloid leukemia gene AML1 is regulated by two promoter regions.Oncogenic role of RUNX3 in head and neck cancer.Role of DNA methylation in head and neck cancer.A PEBP2 alpha/AML-1-related factor increases osteocalcin promoter activity through its binding to an osteoblast-specific cis-acting element.Regulation of collagenase-3 gene expression in osteoblastic and non-osteoblastic cell lines.Quantitative assessment of RUNX3 methylation in neoplastic and non-neoplastic gastric epithelia using a DNA microarray.Solution properties of the free and DNA-bound Runt domain of AML1.Mutual activation of Ets-1 and AML1 DNA binding by direct interaction of their autoinhibitory domains.Cbfa1 isoforms exert functional differences in osteoblast differentiation.Runx1 Structure and Function in Blood Cell Development.UnPAKing RUNX3 functions-Both sides of the coin.
P2860
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P2860
Cloning, mapping and expression of PEBP2 alpha C, a third gene encoding the mammalian Runt domain
description
1995 nî lūn-bûn
@nan
1995 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Cloning, mapping and expressio ...... ding the mammalian Runt domain
@ast
Cloning, mapping and expressio ...... ding the mammalian Runt domain
@en
Cloning, mapping and expressio ...... ding the mammalian Runt domain
@en-gb
Cloning, mapping and expressio ...... ding the mammalian Runt domain
@nl
type
label
Cloning, mapping and expressio ...... ding the mammalian Runt domain
@ast
Cloning, mapping and expressio ...... ding the mammalian Runt domain
@en
Cloning, mapping and expressio ...... ding the mammalian Runt domain
@en-gb
Cloning, mapping and expressio ...... ding the mammalian Runt domain
@nl
prefLabel
Cloning, mapping and expressio ...... ding the mammalian Runt domain
@ast
Cloning, mapping and expressio ...... ding the mammalian Runt domain
@en
Cloning, mapping and expressio ...... ding the mammalian Runt domain
@en-gb
Cloning, mapping and expressio ...... ding the mammalian Runt domain
@nl
P2093
P1433
P1476
Cloning, mapping and expressio ...... ding the mammalian Runt domain
@en
P2093
E Takahashi
K Shigesada
P356
10.1016/0378-1119(95)00060-J
P407
P577
1995-07-04T00:00:00Z