A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia - Wikidata - awgldk - TriplyDB

A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia

A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia

http://www.wikidata.org/entity/Q24652629

about

Bone morphogenetic protein 2-induced osteoblast differentiation requires Smad-mediated down-regulation of Cdk6 Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter Repression of Runx2 by androgen receptor (AR) in osteoblasts and prostate cancer cells: AR binds Runx2 and abrogates its recruitment to DNA CHIP promotes Runx2 degradation and negatively regulates osteoblast differentiation An important role for RUNX3 in human L1 transcription and retrotransposition Transcriptional regulatory cascades in Runx2-dependent bone development TGF-β signaling in C. elegans TGF-β and BMP signaling in osteoblast differentiation and bone formation A pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturation Molecular and cellular aspects of calcific aortic valve disease Mutations in the RUNX2 gene in patients with cleidocranial dysplasia Dimerization with PEBP2beta protects RUNX1/AML1 from ubiquitin-proteasome-mediated degradation BRITER: a BMP responsive osteoblast reporter cell line The interferon-inducible p204 protein acts as a transcriptional coactivator of Cbfa1 and enhances osteoblast differentiation Bone-specific transcription factor Runx2 interacts with the 1alpha,25-dihydroxyvitamin D3 receptor to up-regulate rat osteocalcin gene expression in osteoblastic cells BMP-2-induced Runx2 expression is mediated by Dlx5, and TGF-beta 1 opposes the BMP-2-induced osteoblast differentiation by suppression of Dlx5 expression Parathyroid hormone-Smad3 axis exerts anti-apoptotic action and augments anabolic action of transforming growth factor beta in osteoblasts Mitotic partitioning and selective reorganization of tissue-specific transcription factors in progeny cells Cbfbeta interacts with Runx2 and has a critical role in bone development Foxo1 mediates insulin-like growth factor 1 (IGF1)/insulin regulation of osteocalcin expression by antagonizing Runx2 in osteoblasts Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter Nuclear Export of Smads by RanBP3L Regulates Bone Morphogenetic Protein Signaling and Mesenchymal Stem Cell Differentiation Non-virus-mediated transfer of siRNAs against Runx2 and Smad4 inhibit heterotopic ossification in rats.Tissue-specific calibration of extracellular matrix material properties by transforming growth factor-β and Runx2 in bone is required for hearing The roles of extracellular signal-regulated kinase 1/2 pathway in regulating osteogenic differentiation of murine preosteoblasts MC3T3-E1 cells on roughened titanium surfaces.Opposite Smad and chicken ovalbumin upstream promoter transcription factor inputs in the regulation of the collagen VII gene promoter by transforming growth factor-beta.Smad signaling in skeletal development and regeneration.Dual roles of smad proteins in the conversion from myoblasts to osteoblastic cells by bone morphogenetic proteins.TIEG1/KLF10 modulates Runx2 expression and activity in osteoblasts.The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts.Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites.Stimulation of bone formation and prevention of bone loss by prostaglandin E EP4 receptor activation.Biological regulation of bone quality.Bone morphogenetic protein-2-induced signaling and osteogenesis is regulated by cell shape, RhoA/ROCK, and cytoskeletal tension miR-764-5p promotes osteoblast differentiation through inhibition of CHIP/STUB1 expression.Glutamine repeat variants in human RUNX2 associated with decreased femoral neck BMD, broadband ultrasound attenuation and target gene transactivation Expression pattern, regulation, and biological role of runt domain transcription factor, run, in Caenorhabditis elegans The novel PIAS-like protein hZimp10 enhances Smad transcriptional activity.The Runt-related transcription factor 1 in prostate cancer-associated fibroblasts The RUNX3 tumor suppressor upregulates Bim in gastric epithelial cells undergoing transforming growth factor beta-induced apoptosis.

P2860

Q24299331-09E3C969-40B5-4538-9A99-9241E24981F3 Q24537942-6238080E-8106-49CB-9E92-D26666F3282F Q24641909-D434D9B1-42D9-4F8A-B892-1D954A5AE170 Q24656900-5F3E5DAC-44C6-4C83-B4C1-51BC62B64893 Q24670621-792A5D24-E7DA-4F37-ACFD-27C1DD95210C Q26830666-A55B61B9-742D-4E87-8635-7986D0DD4124 Q26850420-4A7E8BC6-63C9-4AB8-A94C-BA4690A88F58 Q26995720-D1146C78-C5EA-4DFA-A929-F604011F3E3E Q26995910-6AA5591B-BCB7-4269-943D-12D0D5DF36F7 Q27026105-C25112A5-30C2-4A26-8284-9D5C94EBB3F2 Q28202887-19B9914B-A2F5-47BC-B0F6-403EAE5AEDE9 Q28348865-F68679C9-5162-4942-8EA7-A41A9B05DCB6 Q28483777-75CEAAC9-7AD7-4FFF-8150-9D043664FBFA Q28506894-AD313AB9-3180-4AA4-91AB-14E2FF0AD97C Q28565698-A7B94BB8-EE34-4402-8E2E-D6788BA4D76E Q28570736-71DFDD22-F3F3-46FC-89AD-9194F701DA54 Q28573174-7366E473-7857-4473-B408-ED53E4414F1E Q28573678-D11156CB-BFFB-48E0-955E-A0E3B00615FA Q28586662-D336E2BF-1A5B-4F66-AE45-E5EC5BE7B59E Q28591040-2061CCD3-4F89-4AD5-B5C9-A4FEDA5906CD Q28593503-06F0289E-45DC-4ABC-85BE-14ABAB838C37 Q28941240-E409026E-D9AE-4DF6-97A0-6DF11F5BA823 Q30273970-A8CD55FC-B454-4A7A-986E-347140EEBB42 Q30496822-96593780-CDEA-4CDC-9E41-D3DC5ABD4544 Q31035872-B00F344D-C3E5-4ED5-8EB7-C95D22E269E2 Q33200353-129DBADA-46C8-4CAC-9A34-E26EFC500288 Q33674328-FA7A52C5-AADF-46EC-8DC9-4FEC96E6A77A Q33832595-7454E79A-CC55-4C94-BFF3-751DF0853E6D Q33894869-6E3372BA-DED7-478E-8335-26381EEA05A3 Q33953806-184F0A11-519A-4992-A2AF-C92384D5B5DB Q34031066-6687175A-0566-4660-8D27-479F28F51637 Q34049104-6AD585CA-4182-4DB7-9856-8FD213D115EF Q34051287-D5C49E29-F30F-4597-B3F9-6762C12DDA6A Q34221060-D7F9346D-6CA2-490C-84B4-B1A3B985E4A0 Q34260429-37C89D15-9EB0-4CB2-92AC-BBA54A5DA599 Q34388792-27457F62-63F9-46CA-8BDF-D169A4F15B0E Q34440372-57598BF3-BBA5-4E67-86BA-7A607108F751 Q34538658-88748C95-A7A2-4F13-B69A-7F3BFC393EA6 Q34581047-758E03E1-15B6-4BCF-B732-32892EBDA509 Q34718167-3F1D8C12-F2FF-42DC-987B-8862806FCFDF

P2860

A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia

http://www.wikidata.org/entity/Q24652629

description

2000 nî lūn-bûn

@nan

2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2000年の論文

@ja

2000年論文

@yue

2000年論文

@zh-hant

2000年論文

@zh-hk

2000年論文

@zh-mo

2000年論文

@zh-tw

2000年论文

@wuu

name

A RUNX2/PEBP2alpha A/CBFA1 mut ...... ion in cleidocranial dysplasia

@ast

A RUNX2/PEBP2alpha A/CBFA1 mut ...... ion in cleidocranial dysplasia

@en

A RUNX2/PEBP2alpha A/CBFA1 mut ...... ion in cleidocranial dysplasia

@nl

type

label

A RUNX2/PEBP2alpha A/CBFA1 mut ...... ion in cleidocranial dysplasia

@ast

A RUNX2/PEBP2alpha A/CBFA1 mut ...... ion in cleidocranial dysplasia

@en

A RUNX2/PEBP2alpha A/CBFA1 mut ...... ion in cleidocranial dysplasia

@nl

prefLabel

A RUNX2/PEBP2alpha A/CBFA1 mut ...... ion in cleidocranial dysplasia

@ast

A RUNX2/PEBP2alpha A/CBFA1 mut ...... ion in cleidocranial dysplasia

@en

A RUNX2/PEBP2alpha A/CBFA1 mut ...... ion in cleidocranial dysplasia

@nl

P1433

Q24652629-A65957F2-B3EC-486F-99FD-D7E0F602D422

P1476

Q24652629-37B9EA1B-86C1-499D-BCCB-5D243E62D122

P2093

Q24652629-54C58288-C121-41DC-B850-CE3E10B1F7CF

Q24652629-621320FF-34BD-4A9A-B552-6AC37CD26E57

Q24652629-73E83FEA-EC28-49E4-BDBC-D2813579568A

Q24652629-89CBE228-6C63-4704-8249-2537FFB8C203

Q24652629-90D8B700-6E95-4941-BB15-C301D3B1D40D

Q24652629-96C1A72C-F334-45DF-9703-82D3745DCF60

Q24652629-97AF5479-A39D-49A2-ABFC-DC674F654AFF

Q24652629-BC88FC03-4612-460B-B4F4-589D288A0710

Q24652629-C8926D46-E42C-4E66-B52B-9DAD786E06B6

Q24652629-F02BE72D-5C82-48B2-9BA1-E13F1BA58644

P2860

Q24652629-02A6D295-F038-4FB3-8B1C-C0D533F6E72A

Q24652629-0786BA98-6C10-4D51-8CF3-463DB8C7C0DD

Q24652629-099BD550-18BD-4AE3-8620-2FFD9A449250

Q24652629-2A629098-BCAA-447E-9D10-113658B7003F

Q24652629-38362C1E-268B-40DF-AE16-14E361FBC28A

Q24652629-3D7023D8-53A4-4B6C-9613-C423B17727C7

Q24652629-41280604-1F4A-4C77-95BC-5D32A6A31568

Q24652629-45DB23F6-A516-44BC-B63C-5E77227B3A36

Q24652629-45DD32C1-6930-46A0-A12C-FA34896D8943

Q24652629-48878B7A-85C0-4704-BD76-7150921538B7

P304

Q24652629-DA1F7884-3974-49AB-B479-63D26404CB60

P31

Q24652629-465846E1-5975-4A2A-A0CF-38DA2DABF6F0

P356

Q24652629-20A7E8AA-5936-43F7-8F83-B2176B923241

P407

Q24652629-248C026D-85AB-4A4C-9DED-D11CB1143353

P433

Q24652629-D28A56CA-1084-49AD-B15B-3FCBBAA81A83

P478

Q24652629-C4C452AA-77E1-4E40-AF2E-284181EC0667

P577

Q24652629-B670B25A-9648-41AF-A14F-9A20763D948E

P5875

Q24652629-0E85BF9A-91C7-4B09-A75E-66FDE226FA51

P698

Q24652629-57A2C182-840C-49BE-AA2E-B09184F0A6F6

P932

Q24652629-C5727E5B-BFCA-41D3-9D1D-714173DA78CB

P356

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

A RUNX2/PEBP2alpha A/CBFA1 mut ...... ion in cleidocranial dysplasia

@en

P2093

G Huang

http://www.w3.org/2001/XMLSchema#string

H Nogami

http://www.w3.org/2001/XMLSchema#string

J Hanai

http://www.w3.org/2001/XMLSchema#string

K Ito

http://www.w3.org/2001/XMLSchema#string

K Miyazono

http://www.w3.org/2001/XMLSchema#string

M Fujii

http://www.w3.org/2001/XMLSchema#string

N Yasui

http://www.w3.org/2001/XMLSchema#string

T Ochi

http://www.w3.org/2001/XMLSchema#string

Y Ito

http://www.w3.org/2001/XMLSchema#string

Y W Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

TGF-beta signal transduction

Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia

AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization

A novel transcript encoding an N-terminally truncated AML1/PEBP2 alphaB protein interferes with transactivation and blocks granulocytic differentiation of 32Dcl3 myeloid cells

Subcellular localization of the alpha and beta subunits of the acute myeloid leukemia-linked transcription factor PEBP2/CBF

Identification of a new murine runt domain-containing gene, Cbfa3, and localization of the human homolog, CBFA3, to chromosome 1p35-pter

Cloning, mapping and expression of PEBP2 alpha C, a third gene encoding the mammalian Runt domain

Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter

P304

10549-54

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.180309597

http://www.w3.org/2001/XMLSchema#string

P407

P433

19

http://www.w3.org/2001/XMLSchema#string

P478

97

http://www.w3.org/2001/XMLSchema#string

P577

2000-09-12T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

12360059

http://www.w3.org/2001/XMLSchema#string

P698

10962029

http://www.w3.org/2001/XMLSchema#string

P932

27062

http://www.w3.org/2001/XMLSchema#string