A comprehensive functional analysis of PTEN mutations: implications in tumor- and autism-related syndromes
about
Balancing Proliferation and Connectivity in PTEN-associated Autism Spectrum DisorderThe neurology of mTORUsing CellMiner 1.6 for Systems Pharmacology and Genomic Analysis of the NCI-60Potential for treatment of severe autism in tuberous sclerosis complexSubcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disordersThe parvalbumin/somatostatin ratio is increased in Pten mutant mice and by human PTEN ASD alleles.Fine-Tuning of PI3K/AKT Signalling by the Tumour Suppressor PTEN Is Required for Maintenance of Flight Muscle Function and Mitochondrial Integrity in Ageing Adult Drosophila melanogasterDiscovery of Rare Mutations in Autism: Elucidating Neurodevelopmental MechanismsPTEN regulates cilia through Dishevelled.The intrinsically disordered tails of PTEN and PTEN-L have distinct roles in regulating substrate specificity and membrane activityA functional dissection of PTEN N-terminus: implications in PTEN subcellular targeting and tumor suppressor activityOne-Tube-Only Standardized Site-Directed Mutagenesis: An Alternative Approach to Generate Amino Acid Substitution CollectionsERK-mediated NF-κB activation through ASIC1 in response to acidosisThe determinants of head and neck cancer: Unmasking the PI3K pathway mutationsStructural mutation analysis of PTEN and its genotype-phenotype correlations in endometriosis and cancerGermline disruption of Pten localization causes enhanced sex-dependent social motivation and increased glial production.Combined PTEN Mutation and Protein Expression Associate with Overall and Disease-Free Survival of Glioblastoma Patients.Hippocampal granule cell pathology in epilepsy - a possible structural basis for comorbidities of epilepsy?Increased prevalence of eosinophilic gastrointestinal disorders in pediatric PTEN hamartoma tumor syndromesFunctionally distinct groups of inherited PTEN mutations in autism and tumour syndromesA unified nomenclature and amino acid numbering for human PTEN.Conformational stability and catalytic activity of PTEN variants linked to cancers and autism spectrum disorders.Expanding the phenotype of mutations in DICER1: mosaic missense mutations in the RNase IIIb domain of DICER1 cause GLOW syndrome.A Retrospective Evaluation of Vemurafenib as Treatment for BRAF-Mutant Melanoma Brain Metastases.HMMvar-func: a new method for predicting the functional outcome of genetic variants.Autism Linked to Increased Oncogene Mutations but Decreased Cancer Rate.Model-based global sensitivity analysis as applied to identification of anti-cancer drug targets and biomarkers of drug resistance in the ErbB2/3 network.Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240.Lighting a path: genetic studies pinpoint neurodevelopmental mechanisms in autism and related disorders.Role of DNA secondary structures in fragile site breakage along human chromosome 10Cowden syndrome-related mutations in PTEN associate with enhanced proteasome activity.Acquired resistance to combination treatment through loss of synergy with MEK and PI3K inhibitors in colorectal cancer.The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma.Ursolic Acid-Regulated Energy Metabolism-Reliever or Propeller of Ultraviolet-Induced Oxidative Stress and DNA Damage?Establishment of a novel cellular model for myxofibrosarcoma heterogeneity.Plasticity and mTOR: towards restoration of impaired synaptic plasticity in mTOR-related neurogenetic disordersSynaptic basis of social dysfunction: a focus on postsynaptic proteins linking group-I mGluRs with AMPARs and NMDARs.Engineering PTEN function: membrane association and activity.Controlling PTEN (Phosphatase and Tensin Homolog) Stability: A DOMINANT ROLE FOR LYSINE 66.Somatic overgrowth disorders of the PI3K/AKT/mTOR pathway & therapeutic strategies.
P2860
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P2860
A comprehensive functional analysis of PTEN mutations: implications in tumor- and autism-related syndromes
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A comprehensive functional ana ...... - and autism-related syndromes
@ast
A comprehensive functional ana ...... - and autism-related syndromes
@en
A comprehensive functional ana ...... - and autism-related syndromes
@en-gb
A comprehensive functional ana ...... - and autism-related syndromes
@nl
type
label
A comprehensive functional ana ...... - and autism-related syndromes
@ast
A comprehensive functional ana ...... - and autism-related syndromes
@en
A comprehensive functional ana ...... - and autism-related syndromes
@en-gb
A comprehensive functional ana ...... - and autism-related syndromes
@nl
prefLabel
A comprehensive functional ana ...... - and autism-related syndromes
@ast
A comprehensive functional ana ...... - and autism-related syndromes
@en
A comprehensive functional ana ...... - and autism-related syndromes
@en-gb
A comprehensive functional ana ...... - and autism-related syndromes
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
A comprehensive functional ana ...... - and autism-related syndromes
@en
P2093
María D Oliver
María Molina
Víctor J Cid
P2860
P304
P3181
P356
10.1093/HMG/DDR337
P407
P577
2011-08-09T00:00:00Z