Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation
about
The E3 ligase Smurf1 regulates Wolfram syndrome protein stability at the endoplasmic reticulumSCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1Binding of RhoA by the C2 domain of E3 ligase Smurf1 is essential for Smurf1-regulated RhoA ubiquitination and cell protrusive activityREGgamma proteasome mediates degradation of the ubiquitin ligase Smurf1HECT ubiquitin ligase Smurf1 targets the tumor suppressor ING2 for ubiquitination and degradationUbiquitin in the activation and attenuation of innate antiviral immunityKey role for ubiquitin protein modification in TGFβ signal transductionSmurf1-mediated axin ubiquitination requires Smurf1 C2 domain and is cell cycle-dependentCarboxyl terminus of Hsp70-interacting protein regulation of osteoclast formation in mice through promotion of tumor necrosis factor receptor-associated factor 6 protein degradation.IκB kinase α phosphorylation of TRAF4 downregulates innate immune signaling.The phosphoinositide-binding protein TRAF4 modulates tight junction stability and migration of cancer cells.Pivotal role of the C2 domain of the Smurf1 ubiquitin ligase in substrate selectionTRAF4-SMURF2-mediated DAZAP2 degradation is critical for IL-25 signaling and allergic airway inflammation.Smurf1 protein negatively regulates interferon-γ signaling through promoting STAT1 protein ubiquitination and degradation.A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation.Ubiquitination of tumor necrosis factor receptor-associated factor 4 (TRAF4) by Smad ubiquitination regulatory factor 1 (Smurf1) regulates motility of breast epithelial and cancer cellsTRAF4, at the Crossroad between Morphogenesis and Cancer.Smurf1-mediated Lys29-linked nonproteolytic polyubiquitination of axin negatively regulates Wnt/β-catenin signalingSmurf control in bone cells.A Smurf1 tale: function and regulation of an ubiquitin ligase in multiple cellular networks.Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation.Smad6-specific recruitment of Smurf E3 ligases mediates TGF-β1-induced degradation of MyD88 in TLR4 signalling.Depletion of the 26S proteasome adaptor Ecm29 increases Toll-like receptor 3 signaling.Involvement of BMPs/Smad signaling pathway in mechanical response in osteoblasts.Up-regulation of Smurf1 after spinal cord injury in adult rats.[TRAF4, a multifaceted protein involved in carcinoma progression].Induction of OTUD1 by RNA viruses potently inhibits innate immune responses by promoting degradation of the MAVS/TRAF3/TRAF6 signalosome.The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development.
P2860
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P2860
Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation
@ast
Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation
@en
Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation
@en-gb
Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation
@nl
type
label
Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation
@ast
Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation
@en
Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation
@en-gb
Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation
@nl
prefLabel
Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation
@ast
Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation
@en
Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation
@en-gb
Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation
@nl
P2093
P921
P1476
Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation
@en
P2093
Guichun Xing
Guiwen Yang
Lingqiang Zhang
P2888
P356
10.1007/S11010-009-0315-Y
P407
P577
2010-05-01T00:00:00Z
P6179
1031544581