Smad6-specific recruitment of Smurf E3 ligases mediates TGF-β1-induced degradation of MyD88 in TLR4 signalling.
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Ubiquitin in the activation and attenuation of innate antiviral immunityKey role for ubiquitin protein modification in TGFβ signal transductionThe WNT signaling pathway contributes to dectin-1-dependent inhibition of Toll-like receptor-induced inflammatory signatureStatistical genetic analysis of serological measures of common, chronic infections in Alaska Native participants in the GOCADAN study.Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88.Porphyromonas gingivalis manipulates complement and TLR signaling to uncouple bacterial clearance from inflammation and promote dysbiosis.Kaposi's sarcoma-associated herpesvirus-encoded replication and transcription activator impairs innate immunity via ubiquitin-mediated degradation of myeloid differentiation factor 88Inhibition of lethal inflammatory responses through the targeting of membrane-associated Toll-like receptor 4 signaling complexes with a Smad6-derived peptide.Small interference RNA targeting TLR4 gene effectively attenuates pulmonary inflammation in a rat modelSmad7 Modulates Epidermal Growth Factor Receptor Turnover through Sequestration of c-Cbl.Smurf1 protein negatively regulates interferon-γ signaling through promoting STAT1 protein ubiquitination and degradation.Deubiquitinase CYLD acts as a negative regulator for bacterium NTHi-induced inflammation by suppressing K63-linked ubiquitination of MyD88.Ubiquitination in the antiviral immune responseThe Smurf ubiquitin ligases regulate tissue separation via antagonistic interactions with ephrinB1.Soft Elasticity-Associated Signaling and Bone Morphogenic Protein 2 Are Key Regulators of Mesenchymal Stem Cell Spheroidal Aggregates.Syndecan-2 exerts antifibrotic effects by promoting caveolin-1-mediated transforming growth factor-β receptor I internalization and inhibiting transforming growth factor-β1 signaling.Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes.Atractylenolide-I sensitizes human ovarian cancer cells to paclitaxel by blocking activation of TLR4/MyD88-dependent pathway.A Smurf1 tale: function and regulation of an ubiquitin ligase in multiple cellular networks.Molecular mechanisms of regulation of Toll-like receptor signalingRegulation of TGF-β Family Signaling by Inhibitory Smads.Smad6 suppresses the growth and self-renewal of hepatic progenitor cells.Posttranslational Modification as a Critical Determinant of Cytoplasmic Innate Immune Recognition.Stk38 protein kinase preferentially inhibits TLR9-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages.Follistatin alleviates synovitis and articular cartilage degeneration induced by carrageenanBone Morphogenetic Protein 9 Enhances Lipopolysaccharide-Induced Leukocyte Recruitment to the Vascular Endothelium.Mechanism of ubiquitin chain synthesis employed by a HECT domain ubiquitin ligase.Antimicrobial Peptide Epinecidin-1 Modulates MyD88 Protein Levels via the Proteasome Degradation Pathway.The Role of Smurf1 in Neuronal Necroptosis after Lipopolysaccharide-Induced Neuroinflammation.Microglial Activation Results in Inhibition of TGF-β-Regulated Gene Expression.Smurf1 controls S phase progression and tumorigenesis through Wee1 degradation.Up-regulation of Smurf1 after spinal cord injury in adult rats.MyD88 Adaptor Protein Is Required for Appropriate Hepcidin Induction in Response to Dietary Iron Overload in Mice.Nuclear Smad6 promotes gliomagenesis by negatively regulating PIAS3-mediated STAT3 inhibition.MyD88 Regulates the Expression of SMAD4 and the Iron Regulatory Hormone Hepcidin
P2860
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P2860
Smad6-specific recruitment of Smurf E3 ligases mediates TGF-β1-induced degradation of MyD88 in TLR4 signalling.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Smad6-specific recruitment of ...... n of MyD88 in TLR4 signalling.
@en
Smad6-specific recruitment of ...... n of MyD88 in TLR4 signalling.
@nl
type
label
Smad6-specific recruitment of ...... n of MyD88 in TLR4 signalling.
@en
Smad6-specific recruitment of ...... n of MyD88 in TLR4 signalling.
@nl
prefLabel
Smad6-specific recruitment of ...... n of MyD88 in TLR4 signalling.
@en
Smad6-specific recruitment of ...... n of MyD88 in TLR4 signalling.
@nl
P2093
P2860
P356
P1476
Smad6-specific recruitment of ...... n of MyD88 in TLR4 signalling.
@en
P2093
Jae Young Lee
Jin Seok Park
Jun Hwan Kim
Seok Hee Park
Seong-Jin Kim
Su Myung Jung
Youn Sook Lee
P2860
P2888
P356
10.1038/NCOMMS1469
P407
P577
2011-09-06T00:00:00Z