Wwp2, an E3 ubiquitin ligase that targets transcription factor Oct-4 for ubiquitination
about
WWP2 promotes degradation of transcription factor OCT4 in human embryonic stem cellsThe HECT-type E3 ubiquitin ligase AIP2 inhibits activation-induced T-cell death by catalyzing EGR2 ubiquitinationSelective targeting of activating and inhibitory Smads by distinct WWP2 ubiquitin ligase isoforms differentially modulates TGFβ signalling and EMTRegulation of p53 localization and transcription by the HECT domain E3 ligase WWP1Stem cell research in ChinaThe Importance of Ubiquitination and Deubiquitination in Cellular ReprogrammingThe Oct4 protein: more than a magic stemness markerAn expanded Oct4 interaction network: implications for stem cell biology, development, and diseaseProtein kinase Cdelta stimulates proteasome-dependent degradation of C/EBPalpha during apoptosis induction of leukemic cellsWwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25Wwp2 mediates Oct4 ubiquitination and its own auto-ubiquitination in a dosage-dependent mannerRufy3, a protein specifically expressed in neurons, interacts with actin-bundling protein Fascin to control the growth of axonsPost-translational regulation of Oct4 transcriptional activityData in support of DPF2 regulates OCT4 protein level and nuclear distribution.Oct4A is expressed by a subpopulation of prostate neuroendocrine cells.Unfolded protein response is required for the definitive endodermal specification of mouse embryonic stem cells via Smad2 and β-catenin signaling.MiR-25 regulates Wwp2 and Fbxw7 and promotes reprogramming of mouse fibroblast cells to iPSCs.Role of Oct4 in maintaining and regaining stem cell pluripotency.Dual functions of T-box 3 (Tbx3) in the control of self-renewal and extraembryonic endoderm differentiation in mouse embryonic stem cellsThe E3 ubiquitin ligase Wwp2 regulates craniofacial development through mono-ubiquitylation of GoosecoidWWP2 is overexpressed in human oral cancer, determining tumor size and poor prognosis in patients: downregulation of WWP2 inhibits the AKT signaling and tumor growth in mice.A Krüppel-like factor downstream of the E3 ligase WWP-1 mediates dietary-restriction-induced longevity in Caenorhabditis elegans.Prolonged proteasome inhibition cyclically upregulates Oct3/4 and Nanog gene expression, but reduces induced pluripotent stem cell colony formation.Viral and cellular requirements for the budding of feline endogenous retrovirus RD-114.Loss of microRNA-27b contributes to breast cancer stem cell generation by activating ENPP1.Wwp2-mediated ubiquitination of the RNA polymerase II large subunit in mouse embryonic pluripotent stem cellsTransient inhibition of cell proliferation does not compromise self-renewal of mouse embryonic stem cellsDirect conversion of mouse fibroblasts to GABAergic neurons with combined medium without the introduction of transcription factors or miRNAsTRIM32 modulates pluripotency entry and exit by directly regulating Oct4 stabilityCritical POU domain residues confer Oct4 uniqueness in somatic cell reprogramming.Differential role for transcription factor Oct4 nucleocytoplasmic dynamics in somatic cell reprogramming and self-renewal of embryonic stem cellsOct transcription factors in development and stem cells: insights and mechanisms.MicroRNA-195 targets ADP-ribosylation factor-like protein 2 to induce apoptosis in human embryonic stem cell-derived neural progenitor cells.X-inactivation and X-reactivation: epigenetic hallmarks of mammalian reproduction and pluripotent stem cells.PARP1 poly(ADP-ribosyl)ates Sox2 to control Sox2 protein levels and FGF4 expression during embryonic stem cell differentiationWWP2 is an E3 ubiquitin ligase for PTEN.Regulation of stem cell function by protein ubiquitylationPost-translational modulation of pluripotency.WWP2: a multifunctional ubiquitin ligase gene.Autophagy regulates homeostasis of pluripotency-associated proteins in hESCs.
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P248
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P2860
Wwp2, an E3 ubiquitin ligase that targets transcription factor Oct-4 for ubiquitination
description
2004 nî lūn-bûn
@nan
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Wwp2, an E3 ubiquitin ligase that targets transcription factor Oct-4 for ubiquitination
@ast
Wwp2, an E3 ubiquitin ligase that targets transcription factor Oct-4 for ubiquitination
@en
Wwp2, an E3 ubiquitin ligase that targets transcription factor Oct-4 for ubiquitination
@en-gb
Wwp2, an E3 ubiquitin ligase that targets transcription factor Oct-4 for ubiquitination
@nl
type
label
Wwp2, an E3 ubiquitin ligase that targets transcription factor Oct-4 for ubiquitination
@ast
Wwp2, an E3 ubiquitin ligase that targets transcription factor Oct-4 for ubiquitination
@en
Wwp2, an E3 ubiquitin ligase that targets transcription factor Oct-4 for ubiquitination
@en-gb
Wwp2, an E3 ubiquitin ligase that targets transcription factor Oct-4 for ubiquitination
@nl
prefLabel
Wwp2, an E3 ubiquitin ligase that targets transcription factor Oct-4 for ubiquitination
@ast
Wwp2, an E3 ubiquitin ligase that targets transcription factor Oct-4 for ubiquitination
@en
Wwp2, an E3 ubiquitin ligase that targets transcription factor Oct-4 for ubiquitination
@en-gb
Wwp2, an E3 ubiquitin ligase that targets transcription factor Oct-4 for ubiquitination
@nl
P2093
P921
P356
P1476
Wwp2, an E3 ubiquitin ligase that targets transcription factor Oct-4 for ubiquitination
@en
P2093
Bei Bei Wang
Hui Ming Xu
Hui Zhen Sheng
Qian Jun Zhang
Xiao Min Zhong
Ying Ming Zhao
Ying Xin Zhao
P304
P356
10.1074/JBC.M400516200
P407
P577
2004-05-28T00:00:00Z