Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum
about
Cloning and characterization of a mammalian prenyl protein-specific proteaseIdentification and characterization of a novel factor that regulates quinone reductase gene transcriptional activityIsoprenylcysteine carboxyl methyltransferase deficiency in miceInhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndromeIsoprenylcysteine carboxyl methyltransferase activity modulates endothelial cell apoptosisTopological and mutational analysis of Saccharomyces cerevisiae Ste14p, founding member of the isoprenylcysteine carboxyl methyltransferase familyInactivation of Icmt inhibits transformation by oncogenic K-Ras and B-RafExploitation of eukaryotic subcellular targeting mechanisms by bacterial effectorsA methylated phosphate group and four amide-linked acyl chains in leptospira interrogans lipid A. The membrane anchor of an unusual lipopolysaccharide that activates TLR2Model of human aging: recent findings on Werner's and Hutchinson-Gilford progeria syndromesDual roles for Ste24p in yeast a-factor maturation: NH2-terminal proteolysis and COOH-terminal CAAX processingTargeting Ras signaling through inhibition of carboxyl methylation: an unexpected property of methotrexateA carboxyl-terminal interaction of lamin B1 is dependent on the CAAX endoprotease Rce1 and carboxymethylationDifferential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI bindingInhibition of ICMT induces endothelial cell apoptosis through GRP94GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivoAnalysis of the kinetic mechanism of recombinant human isoprenylcysteine carboxylmethyltransferase (Icmt)The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidizedErf2, a novel gene product that affects the localization and palmitoylation of Ras2 in Saccharomyces cerevisiae.Yeast as a tractable genetic system for functional studies of the insulin-degrading enzyme.Guanine nucleotide exchange factors (GEFs) have a critical but not exclusive role in organelle localization of Rab GTPases.A novel Ras inhibitor, Eri1, engages yeast Ras at the endoplasmic reticulum.Chemical inhibition of CaaX protease activity disrupts yeast Ras localization.The Saccharomyces cerevisiae prenylcysteine carboxyl methyltransferase Ste14p is in the endoplasmic reticulum membrane.Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.Analysis of prelamin A biogenesis reveals the nucleus to be a CaaX processing compartmentA non-farnesylated Ha-Ras protein can be palmitoylated and trigger potent differentiation and transformationRas-induced cellular events (review)Laminopathies and the long strange trip from basic cell biology to therapyPrelamin A farnesylation and progeroid syndromesDisruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cellsCloning and characterization of a 72-kDa inositol-polyphosphate 5-phosphatase localized to the Golgi networkTargeted inactivation of the isoprenylcysteine carboxyl methyltransferase gene causes mislocalization of K-Ras in mammalian cellsRas plasma membrane signalling platformsStructural basis for catalysis at the membrane-water interface.Farnesylation of lamin B1 is important for retention of nuclear chromatin during neuronal migration.Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation.Synthesis and application of fluorescent ras proteins for live-cell imaging.Ras, an actor on many stages: posttranslational modifications, localization, and site-specified events.Purification of the CaaX-modified, dynamin-related large GTPase hGBP1 by coexpression with farnesyltransferase
P2860
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P2860
Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum
@ast
Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum
@en
Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum
@en-gb
Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum
@nl
type
label
Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum
@ast
Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum
@en
Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum
@en-gb
Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum
@nl
prefLabel
Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum
@ast
Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum
@en
Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum
@en-gb
Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum
@nl
P2093
P2860
P921
P356
P1476
Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum
@en
P2093
M R Philips
S A Steitz
S Michaelis
S R Slivka
P2860
P304
15030-15034
P356
10.1074/JBC.273.24.15030
P407
P577
1998-06-01T00:00:00Z