Scyl1, mutated in a recessive form of spinocerebellar neurodegeneration, regulates COPI-mediated retrograde traffic
about
Mutation in archain 1, a subunit of COPI coatomer complex, causes diluted coat color and Purkinje cell degenerationGerodermia osteodysplastica is caused by mutations in SCYL1BP1, a Rab-6 interacting golginSCYL pseudokinases in neuronal function and survivalGolgi Fragmentation in ALS Motor Neurons. New Mechanisms Targeting Microtubules, Tethers, and Transport VesiclesHow Rab proteins determine Golgi structureScyl1 regulates Golgi morphologyRules for the recognition of dilysine retrieval motifs by coatomerDENND2B activates Rab13 at the leading edge of migrating cells and promotes metastatic behavior.Loss of yata, a novel gene regulating the subcellular localization of APPL, induces deterioration of neural tissues and lifespan shortening.MAPK signaling to the early secretory pathway revealed by kinase/phosphatase functional screeningA robust methodology to subclassify pseudokinases based on their nucleotide-binding properties.RNAi screen identifies a role for adaptor protein AP-3 in sorting to the regulated secretory pathwayOverexpression of N-terminal kinase like gene promotes tumorigenicity of hepatocellular carcinoma by regulating cell cycle progression and cell motility.SCYL2 Protects CA3 Pyramidal Neurons from Excitotoxicity during Functional Maturation of the Mouse Hippocampus.Fission Yeast SCYL1/2 Homologue Ppk32: A Novel Regulator of TOR Signalling That Governs Survival during Brefeldin A Induced Stress to Protein Trafficking.Disruptive SCYL1 Mutations Underlie a Syndrome Characterized by Recurrent Episodes of Liver Failure, Peripheral Neuropathy, Cerebellar Atrophy, and Ataxia.RNAi screening reveals a large signaling network controlling the Golgi apparatus in human cells.COPII and COPI traffic at the ER-Golgi interface.RNA-binding proteins associated molecular mechanisms of motor neuron degeneration pathogenesis.Systems biology of the secretory pathway: what have we learned so far?COPI transport complexes bind to specific RNAs in neuronal cells.Prediction of endoplasmic reticulum resident proteins using fragmented amino acid composition and support vector machineScyl1 facilitates nuclear tRNA export in mammalian cells by acting at the nuclear pore complex.Kainic Acid-Induced Golgi Complex Fragmentation/Dispersal Shifts the Proteolysis of Reelin in Primary Rat Neuronal Cells: An In Vitro Model of Early Stage Epilepsy.Membrane trafficking heats up in Pavia. Golgi Meeting on Membrane Trafficking in Global Cellular Responses.Copb2 is essential for embryogenesis and hypomorphic mutations cause human microcephaly.Spinocerebellar Ataxia-21 in a Turkish Child.Suppression of the synaptic localization of a subset of proteins including APP partially ameliorates phenotypes of the Drosophila Alzheimer's disease model
P2860
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P2860
Scyl1, mutated in a recessive form of spinocerebellar neurodegeneration, regulates COPI-mediated retrograde traffic
description
2008 nî lūn-bûn
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2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Scyl1, mutated in a recessive ...... PI-mediated retrograde traffic
@ast
Scyl1, mutated in a recessive ...... PI-mediated retrograde traffic
@en
Scyl1, mutated in a recessive ...... PI-mediated retrograde traffic
@en-gb
Scyl1, mutated in a recessive ...... PI-mediated retrograde traffic
@nl
type
label
Scyl1, mutated in a recessive ...... PI-mediated retrograde traffic
@ast
Scyl1, mutated in a recessive ...... PI-mediated retrograde traffic
@en
Scyl1, mutated in a recessive ...... PI-mediated retrograde traffic
@en-gb
Scyl1, mutated in a recessive ...... PI-mediated retrograde traffic
@nl
prefLabel
Scyl1, mutated in a recessive ...... PI-mediated retrograde traffic
@ast
Scyl1, mutated in a recessive ...... PI-mediated retrograde traffic
@en
Scyl1, mutated in a recessive ...... PI-mediated retrograde traffic
@en-gb
Scyl1, mutated in a recessive ...... PI-mediated retrograde traffic
@nl
P2093
P2860
P3181
P356
P1476
Scyl1, mutated in a recessive ...... PI-mediated retrograde traffic
@en
P2093
Jacynthe Philie
John F Presley
Jonathon L Burman
Lyne Bourbonniere
Peter S McPherson
Selma Y Dejgaard
Thomas Stroh
P2860
P304
P3181
P356
10.1074/JBC.M801869200
P407
P577
2008-08-15T00:00:00Z