Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK⁴a regulation
about
A KRAS-directed transcriptional silencing pathway that mediates the CpG island methylator phenotypeThe molecular balancing act of p16(INK4a) in cancer and aging.Major transcriptome re-organisation and abrupt changes in signalling, cell cycle and chromatin regulation at neural differentiation in vivo.HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia.Homeobox gene expression in acute myeloid leukemia is linked to typical underlying molecular aberrations.Inhibition of histone methyltransferase EZH2 depletes leukemia stem cell of mixed lineage leukemia fusion leukemia through upregulation of p16.Formation of a Polycomb-Domain in the Absence of Strong Polycomb Response ElementsAcute myeloid leukemia requires Hhex to enable PRC2-mediated epigenetic repression of Cdkn2aBiochemical and functional interactions of human papillomavirus proteins with polycomb group proteins.Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability.Nuclear reprogramming and its role in vascular smooth muscle cells.H2.0-like homeobox 1 acts as a tumor suppressor in hepatocellular carcinoma.Synthetic lethal targeting of oncogenic transcription factors in acute leukemia by PARP inhibitors.Deregulation of the HOXA9/MEIS1 axis in acute leukemia.Co-regulation of senescence-associated genes by oncogenic homeobox proteins and polycomb repressive complexes.A Role for Cellular Senescence in Birth Timing.The homeoprotein SIX1 controls cellular senescence through the regulation of p16INK4A and differentiation-related genes.Downregulation of PARP1 transcription by promoter-associated E2F4-RBL2-HDAC1-BRM complex contributes to repression of pluripotency stem cell factors in human monocytesSenescence and aging: Causes, consequences, and therapeutic avenues.Mechanisms and functions of cellular senescence.
P2860
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P2860
Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK⁴a regulation
description
2013 nî lūn-bûn
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2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2013 թվականի ապրիլին հրատարակված գիտական հոդված
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2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年學術文章
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name
Interplay between Homeobox pro ...... mplexes in p16INK⁴a regulation
@ast
Interplay between Homeobox pro ...... mplexes in p16INK⁴a regulation
@en
Interplay between Homeobox pro ...... mplexes in p16INK⁴a regulation
@en-gb
Interplay between Homeobox pro ...... mplexes in p16INK⁴a regulation
@nl
type
label
Interplay between Homeobox pro ...... mplexes in p16INK⁴a regulation
@ast
Interplay between Homeobox pro ...... mplexes in p16INK⁴a regulation
@en
Interplay between Homeobox pro ...... mplexes in p16INK⁴a regulation
@en-gb
Interplay between Homeobox pro ...... mplexes in p16INK⁴a regulation
@nl
prefLabel
Interplay between Homeobox pro ...... mplexes in p16INK⁴a regulation
@ast
Interplay between Homeobox pro ...... mplexes in p16INK⁴a regulation
@en
Interplay between Homeobox pro ...... mplexes in p16INK⁴a regulation
@en-gb
Interplay between Homeobox pro ...... mplexes in p16INK⁴a regulation
@nl
P2093
P2860
P50
P3181
P356
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Interplay between Homeobox pro ...... mplexes in p16INK⁴a regulation
@en
P2093
Bernd B Zeisig
Chi Wai Eric So
Efstathia Thymiakou
Francesca Aguilo
Gopuraja Dharmalingam
Gordon Peters
Martin J Walsh
Nikolay Popov
Selina Raguz
P2860
P304
P3181
P356
10.1038/EMBOJ.2013.37
P407
P577
2013-04-03T00:00:00Z