The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells
about
Epigenetic regulation of caloric restriction in agingINK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosisPRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylationSeveral distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locusInterplay between Homeobox proteins and Polycomb repressive complexes in p16INK⁴a regulationUbiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressorEpigenetic regulation of the INK4b-ARF-INK4a locus: in sickness and in healthCovalent histone modifications--miswritten, misinterpreted and mis-erased in human cancersCellular senescence and tumor suppressor gene p16Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor geneMolecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4aEZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotencyPolycomb Repressive Complex 2 and Trithorax modulate Drosophila longevity and stress resistanceExpression of p16(INK4a) in peripheral blood T-cells is a biomarker of human agingHistone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RASHmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf ExpressionImplications of Genetic and Epigenetic Alterations of CDKN2A (p16(INK4a)) in CancerReactivating p53 functions by suppressing its novel inhibitor iASPP: a potential therapeutic opportunity in p53 wild-type tumorsPolycomb Group (PcG) Proteins and Human Cancers: Multifaceted Functions and Therapeutic ImplicationsCommon features of chromatin in aging and cancer: cause or coincidence?Physiological and Pathological Aging Affects Chromatin Dynamics, Structure and Function at the Nuclear EdgeA KRAS-directed transcriptional silencing pathway that mediates the CpG island methylator phenotypeJDP2 (Jun Dimerization Protein 2)-deficient mouse embryonic fibroblasts are resistant to replicative senescenceThe H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescenceEpithelial-mesenchymal transition and cancer stemness: the Twist1-Bmi1 connectionThe histone demethylase UTX enables RB-dependent cell fate controlCoordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2Pathologically decreased miR-26a antagonizes apoptosis and facilitates carcinogenesis by targeting MTDH and EZH2 in breast cancerThe H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15(Ink4b)Defining the toxicology of agingCell reprogramming requires silencing of a core subset of polycomb targetsc-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16INK4a expressionA novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1Polycomb EZH2 controls self-renewal and safeguards the transcriptional identity of skeletal muscle stem cellsInvestigation of the relationship between chromobox homolog 8 and nucleus pulposus cells degeneration in rat intervertebral discAlterations in chromatin are associated with increases in collagen III expression in aging nephropathyEzh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cellsCombined Overexpression of JARID2, PRDM14, ESRRB, and SALL4A Dramatically Improves Efficiency and Kinetics of Reprogramming to Induced Pluripotent Stem Cells.The Polycomb complex PRC2 and its mark in lifeErasing the methyl mark: histone demethylases at the center of cellular differentiation and disease
P2860
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P2860
The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells
description
2007 nî lūn-bûn
@nan
2007 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մարտին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
The Polycomb group proteins bi ...... sassociated in senescent cells
@ast
The Polycomb group proteins bi ...... sassociated in senescent cells
@en
The Polycomb group proteins bi ...... sassociated in senescent cells
@nl
type
label
The Polycomb group proteins bi ...... sassociated in senescent cells
@ast
The Polycomb group proteins bi ...... sassociated in senescent cells
@en
The Polycomb group proteins bi ...... sassociated in senescent cells
@nl
prefLabel
The Polycomb group proteins bi ...... sassociated in senescent cells
@ast
The Polycomb group proteins bi ...... sassociated in senescent cells
@en
The Polycomb group proteins bi ...... sassociated in senescent cells
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
The Polycomb group proteins bi ...... sassociated in senescent cells
@en
P2093
Chantal Beekman
Daniela Kleine-Kohlbrecher
Gaetano Gargiulo
Kim Theilgaard-Mönch
Nikolaj Dietrich
Saverio Minucci
P2860
P304
P3181
P356
10.1101/GAD.415507
P407
P577
2007-03-01T00:00:00Z