Identification and characterization of the endocytic transmembrane glycoprotein Endo180 as a novel collagen receptor
about
Balancing selection of a frame-shift mutation in the MRC2 gene accounts for the outbreak of the Crooked Tail Syndrome in Belgian Blue CattleEndosomes generate localized Rho-ROCK-MLC2-based contractile signals via Endo180 to promote adhesion disassemblyThe collagen receptor uPARAP/Endo180 in tissue degradation and cancer (Review)Tumor-associated Endo180 requires stromal-derived LOX to promote metastatic prostate cancer cell migration on human ECM surfaces.The urokinase receptor (uPAR) and the uPAR-associated protein (uPARAP/Endo180): membrane proteins engaged in matrix turnover during tissue remodelingThe mannose receptoruPARAP function in cutaneous wound repairEndo180 binds to the C-terminal region of type I collagenCaveolin-1-dependent beta1 integrin endocytosis is a critical regulator of fibronectin turnoverM2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway.Up-regulation of uPARAP/Endo180 during culture activation of rat hepatic stellate cells and its presence in hepatic stellate cell lines from different speciesA role for fibrillar collagen deposition and the collagen internalization receptor endo180 in glioma invasion.Fibronectin matrix turnover occurs through a caveolin-1-dependent process.Collagen I matrix turnover is regulated by fibronectin polymerization.Endocytosis of collagen by hepatic stellate cells regulates extracellular matrix dynamics.Pancreatic cancer cells enhance the ability of collagen internalization during epithelial-mesenchymal transition.MRC2 expression correlates with TGFβ1 and survival in hepatocellular carcinoma.Collagen inhibitory peptide R1R2 mediates vascular remodeling by decreasing inflammation and smooth muscle cell activationThe non-phagocytic route of collagen uptake: a distinct degradation pathway.A novel functional role of collagen glycosylation: interaction with the endocytic collagen receptor uparap/ENDO180Lysosomal trafficking of TGFBIp via caveolae-mediated endocytosis.Mannose receptor 2 attenuates renal fibrosisAtelocollagen-mediated systemic delivery prevents immunostimulatory adverse effects of siRNA in mammals.Role of urokinase plasminogen activator receptor-associated protein in mouse lungMigration of intervertebral disc cells into dense collagen scaffolds intended for functional replacement.Complementary roles of intracellular and pericellular collagen degradation pathways in vivo.GPI-anchored uPAR requires Endo180 for rapid directional sensing during chemotaxis.Endo180 modulation by bisphosphonates and diagnostic accuracy in metastatic breast cancer.Complex determinants in specific members of the mannose receptor family govern collagen endocytosisCadherin 99C regulates apical expansion and cell rearrangement during epithelial tube elongation.Human pathogens utilize host extracellular matrix proteins laminin and collagen for adhesion and invasion of the host.Downregulation of uPARAP mediates cytoskeletal rearrangements and decreases invasion and migration properties in glioma cells.Endo180 at the cutting edge of bone cancer treatment and beyond.AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival.TGFβ1-Endo180-dependent collagen deposition is dysregulated at the tumour-stromal interface in bone metastasis.Membrane type-1 matrix metalloproteinase activity is regulated by the endocytic collagen receptor Endo180.Collagen binding by the mannose receptor mediated through the fibronectin type II domain.Insights into Collagen Uptake by C-type Mannose Receptors from the Crystal Structure of Endo180 Domains 1-4A targeted deletion in the endocytic receptor gene Endo180 results in a defect in collagen uptake.Three-dimensional interplay among the ligand-binding domains of the urokinase-plasminogen-activator-receptor-associated protein, Endo180.
P2860
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P2860
Identification and characterization of the endocytic transmembrane glycoprotein Endo180 as a novel collagen receptor
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Identification and characteriz ...... 0 as a novel collagen receptor
@ast
Identification and characteriz ...... 0 as a novel collagen receptor
@en
Identification and characteriz ...... 0 as a novel collagen receptor
@en-gb
Identification and characteriz ...... 0 as a novel collagen receptor
@nl
type
label
Identification and characteriz ...... 0 as a novel collagen receptor
@ast
Identification and characteriz ...... 0 as a novel collagen receptor
@en
Identification and characteriz ...... 0 as a novel collagen receptor
@en-gb
Identification and characteriz ...... 0 as a novel collagen receptor
@nl
prefLabel
Identification and characteriz ...... 0 as a novel collagen receptor
@ast
Identification and characteriz ...... 0 as a novel collagen receptor
@en
Identification and characteriz ...... 0 as a novel collagen receptor
@en-gb
Identification and characteriz ...... 0 as a novel collagen receptor
@nl
P2093
P2860
P921
P356
P1476
Identification and characteriz ...... 0 as a novel collagen receptor
@en
P2093
Clare M Isacke
Dirk Wienke
John R MacFadyen
P2860
P304
P356
10.1091/MBC.E02-12-0814
P407
P577
2003-09-01T00:00:00Z