Ubiquilin recruits Eps15 into ubiquitin-rich cytoplasmic aggregates via a UIM-UBL interaction
about
The ubiquilin gene family: evolutionary patterns and functional insightsCross-species divergence of the major recognition pathways of ubiquitylated substrates for ubiquitin/26S proteasome-mediated proteolysisUSP9x-mediated deubiquitination of EFA6 regulates de novo tight junction assembly.The ubiquitin-like protein PLIC-2 is a negative regulator of G protein-coupled receptor endocytosis.The UBL domain of PLIC-1 regulates aggresome formationUbiquilin-1 is a molecular chaperone for the amyloid precursor proteinUbiquitin-like and ubiquitin-associated domain proteins: significance in proteasomal degradationDimerization of ubiquilin is dependent upon the central region of the protein: evidence that the monomer, but not the dimer, is involved in binding presenilinsAggresome formation and neurodegenerative diseases: therapeutic implicationsThe ubiquitin-like protein PLIC-1 or ubiquilin 1 inhibits TLR3-Trif signalingUbiquitin domain proteins in disease.The Hsc/Hsp70 co-chaperone network controls antigen aggregation and presentation during maturation of professional antigen presenting cells.UBQLN1 interacts with SPEM1 and participates in spermiogenesisTransfer of Ho endonuclease and Ufo1 to the proteasome by the UbL-UbA shuttle protein, Ddi1, analysed by complex formation in vitro.The endocytic adaptor Eps15 controls marginal zone B cell numbersA snapshot of the physical and functional wiring of the Eps15 homology domain network in the nematode.The ubiquitin ligase HERC3 attenuates NF-κB-dependent transcription independently of its enzymatic activity by delivering the RelA subunit for degradationStudies of the role of ubiquitination in the interaction of ubiquilin with the loop and carboxyl terminal regions of presenilin-2PLIC proteins or ubiquilins regulate autophagy-dependent cell survival during nutrient starvation.Aggrephagy: selective disposal of protein aggregates by macroautophagy.Targeting ubiquilin-1 in Alzheimer's disease.Ubiquitin-interacting motifs inhibit aggregation of polyQ-expanded huntingtin.Recruitment of APPL1 to ubiquitin-rich aggresomes in response to proteasomal impairment.Potentiation of amyotrophic lateral sclerosis (ALS)-associated TDP-43 aggregation by the proteasome-targeting factor, ubiquilin 1.Differential interaction of the E3 ligase parkin with the proteasomal subunit S5a and the endocytic protein Eps15.Eps15: a multifunctional adaptor protein regulating intracellular trafficking.Mutation-dependent aggregation and toxicity in a Drosophila model for UBQLN2-associated ALS.UBQLNs bind UIM-containing adaptor proteinsCdc48 and ubiquilins confer selective anterograde protein sorting and entry into the multivesicular body in yeast.
P2860
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P248
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P2860
Ubiquilin recruits Eps15 into ubiquitin-rich cytoplasmic aggregates via a UIM-UBL interaction
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Ubiquilin recruits Eps15 into ...... ates via a UIM-UBL interaction
@ast
Ubiquilin recruits Eps15 into ...... ates via a UIM-UBL interaction
@en
Ubiquilin recruits Eps15 into ...... ates via a UIM-UBL interaction
@en-gb
Ubiquilin recruits Eps15 into ...... ates via a UIM-UBL interaction
@nl
type
label
Ubiquilin recruits Eps15 into ...... ates via a UIM-UBL interaction
@ast
Ubiquilin recruits Eps15 into ...... ates via a UIM-UBL interaction
@en
Ubiquilin recruits Eps15 into ...... ates via a UIM-UBL interaction
@en-gb
Ubiquilin recruits Eps15 into ...... ates via a UIM-UBL interaction
@nl
prefLabel
Ubiquilin recruits Eps15 into ...... ates via a UIM-UBL interaction
@ast
Ubiquilin recruits Eps15 into ...... ates via a UIM-UBL interaction
@en
Ubiquilin recruits Eps15 into ...... ates via a UIM-UBL interaction
@en-gb
Ubiquilin recruits Eps15 into ...... ates via a UIM-UBL interaction
@nl
P2093
P50
P921
P356
P1476
Ubiquilin recruits Eps15 into ...... ates via a UIM-UBL interaction
@en
P2093
Arie Verkleij
Elsa Regan-Klapisz
Irina Sorokina
Jarno Voortman
Lara Fallon
Paul M P van Bergen en Henegouwen
Peter Verheesen
P304
P356
10.1242/JCS.02571
P407
P577
2005-10-01T00:00:00Z