MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria
about
Molecular chaperone function of Mia40 triggers consecutive induced folding steps of the substrate in mitochondrial protein importChChd3, an inner mitochondrial membrane protein, is essential for maintaining crista integrity and mitochondrial functionOrphan proteins of unknown function in the mitochondrial intermembrane space proteome: New pathways and metabolic cross-talkKinetics and mechanisms of thiol-disulfide exchange covering direct substitution and thiol oxidation-mediated pathwaysStructural basis of yeast Tim40/Mia40 as an oxidative translocator in the mitochondrial intermembrane spaceMolecular recognition and substrate mimicry drive the electron-transfer process between MIA40 and ALRFunctional Role of Two Interhelical Disulfide Bonds in Human Cox17 Protein from a Structural PerspectiveStructure of Yeast Sulfhydryl Oxidase Erv1 Reveals Electron Transfer of the Disulfide Relay System in the Mitochondrial Intermembrane SpaceIdentification and characterization of mitochondrial Mia40 as an iron-sulfur protein.Mdm35p imports Ups proteins into the mitochondrial intermembrane space by functional complex formationMia40 is a trans-site receptor that drives protein import into the mitochondrial intermembrane space by hydrophobic substrate binding.Intermembrane space proteome of yeast mitochondria.Atp23 biogenesis reveals a chaperone-like folding activity of Mia40 in the IMS of mitochondria.Oxidative folding in the mitochondrial intermembrane space: A regulated process important for cell physiology and diseaseKey Targets for Multi-Target Ligands Designed to Combat NeurodegenerationCellular disulfide bond formation in bioactive peptides and proteinsCopper metallochaperonesImporting mitochondrial proteins: machineries and mechanismsRole of mitochondrial inner membrane organizing system in protein biogenesis of the mitochondrial outer membrane.Expanding the Range of Protein Function at the Far End of the Order-Structure ContinuumFrom structure to redox: The diverse functional roles of disulfides and implications in disease.A novel intermembrane space-targeting signal docks cysteines onto Mia40 during mitochondrial oxidative folding.Conserved and novel functions for Arabidopsis thaliana MIA40 in assembly of proteins in mitochondria and peroxisomesEuropean contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).Mia40 Protein Serves as an Electron Sink in the Mia40-Erv1 Import Pathway.Oxidative protein biogenesis and redox regulation in the mitochondrial intermembrane space.Mitochondrial Ccs1 contains a structural disulfide bond crucial for the import of this unconventional substrate by the disulfide relay systemThe mitochondrial proteome and human disease.CHCHD2 inhibits apoptosis by interacting with Bcl-x L to regulate Bax activation.Human CHCHD4 mitochondrial proteins regulate cellular oxygen consumption rate and metabolism and provide a critical role in hypoxia signaling and tumor progressionThe MIA pathway: a key regulator of mitochondrial oxidative protein folding and biogenesis.Redox-regulated dynamic interplay between Cox19 and the copper-binding protein Cox11 in the intermembrane space of mitochondria facilitates biogenesis of cytochrome c oxidaseRole of twin Cys-Xaa9-Cys motif cysteines in mitochondrial import of the cytochrome C oxidase biogenesis factor Cmc1.Repurposing Approach Identifies Auranofin with Broad Spectrum Antifungal Activity That Targets Mia40-Erv1 PathwayThe Oxidation Status of Mic19 Regulates MICOS AssemblyIn vivo evidence for cooperation of Mia40 and Erv1 in the oxidation of mitochondrial proteins.Targeting and import mechanism of coiled-coil helix coiled-coil helix domain-containing protein 3 (ChChd3) into the mitochondrial intermembrane space.The ubiquitin-proteasome system regulates mitochondrial intermembrane space proteins.Folding and biogenesis of mitochondrial small Tim proteins.Reconstitution of the mia40-erv1 oxidative folding pathway for the small tim proteins.
P2860
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P2860
MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria
@ast
MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria
@en
MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria
@en-gb
MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria
@nl
type
label
MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria
@ast
MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria
@en
MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria
@en-gb
MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria
@nl
prefLabel
MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria
@ast
MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria
@en
MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria
@en-gb
MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria
@en
P2093
Chiara Cefaro
Dionisia P Sideris
Nitsa Katrakili
P2860
P2888
P304
P3181
P356
10.1038/NSMB.1553
P407
P577
2009-02-01T00:00:00Z
P5875
P6179
1046192120