Reconstitution of the mia40-erv1 oxidative folding pathway for the small tim proteins.
about
Mitochondrial Redox Dysfunction and Environmental ExposuresMdm35p imports Ups proteins into the mitochondrial intermembrane space by functional complex formationMia40 is a trans-site receptor that drives protein import into the mitochondrial intermembrane space by hydrophobic substrate binding.A small molecule inhibitor of redox-regulated protein translocation into mitochondriaMitochondrial protein synthesis, import, and assembly.Mia40 Protein Serves as an Electron Sink in the Mia40-Erv1 Import Pathway.Oxidative protein biogenesis and redox regulation in the mitochondrial intermembrane space.The MIA pathway: a key regulator of mitochondrial oxidative protein folding and biogenesis.Redox-regulated dynamic interplay between Cox19 and the copper-binding protein Cox11 in the intermembrane space of mitochondria facilitates biogenesis of cytochrome c oxidaseRole of twin Cys-Xaa9-Cys motif cysteines in mitochondrial import of the cytochrome C oxidase biogenesis factor Cmc1.In vivo evidence for cooperation of Mia40 and Erv1 in the oxidation of mitochondrial proteins.Role of tryptophan residues of Erv1: Trp95 and Trp183 are important for its folding and oxidase function.The ubiquitin-proteasome system regulates mitochondrial intermembrane space proteins.The power of yeast to model diseases of the powerhouse of the cell.Mitochondrial disulfide relay: redox-regulated protein import into the intermembrane space.Oxidative folding in the mitochondrial intermembrane space in human health and disease.Common players in mitochondria biogenesis and neuronal protection against stress-induced apoptosis.The mitochondrial disulfide relay system: roles in oxidative protein folding and beyond.Role of membrane contact sites in protein import into mitochondria.How lipids modulate mitochondrial protein import.The mitochondrial intermembrane space oxireductase Mia40 funnels the oxidative folding pathway of the cytochrome c oxidase assembly protein Cox19.Mitochondrial disulfide relay and its substrates: mechanisms in health and disease.Glutathione redox potential in the mitochondrial intermembrane space is linked to the cytosol and impacts the Mia40 redox state.Protein oxidation in the intermembrane space of mitochondria is substrate-specific rather than general.Cytosolic thioredoxin system facilitates the import of mitochondrial small Tim proteins.Mitochondrial protein import: Mia40 facilitates Tim22 translocation into the inner membrane of mitochondria.The disease-associated mutation of the mitochondrial thiol oxidase Erv1 impairs cofactor binding during its catalytic reaction.Mia40 and MINOS act in parallel with Ccs1 in the biogenesis of mitochondrial Sod1.Disulfide bond formation: sulfhydryl oxidase ALR controls mitochondrial biogenesis of human MIA40.Osm1 facilitates the transfer of electrons from Erv1 to fumarate in the redox-regulated import pathway in the mitochondrial intermembrane space.Erv1 of Arabidopsis thaliana can directly oxidize mitochondrial intermembrane space proteins in the absence of redox-active Mia40.Protein Translocation into the Intermembrane Space and Matrix of Mitochondria: Mechanisms and Driving Forces.Role of the CPC sequence in the antioxidant activity of GcGAST protein in E.coli.
P2860
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P2860
Reconstitution of the mia40-erv1 oxidative folding pathway for the small tim proteins.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 28 May 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Reconstitution of the mia40-erv1 oxidative folding pathway for the small tim proteins.
@en
Reconstitution of the mia40-erv1 oxidative folding pathway for the small tim proteins.
@nl
type
label
Reconstitution of the mia40-erv1 oxidative folding pathway for the small tim proteins.
@en
Reconstitution of the mia40-erv1 oxidative folding pathway for the small tim proteins.
@nl
prefLabel
Reconstitution of the mia40-erv1 oxidative folding pathway for the small tim proteins.
@en
Reconstitution of the mia40-erv1 oxidative folding pathway for the small tim proteins.
@nl
P2093
P2860
P356
P1476
Reconstitution of the mia40-erv1 oxidative folding pathway for the small tim proteins.
@en
P2093
Carla M Koehler
Deepa V Dabir
Heather L Tienson
Joseph A Loo
Pinmanee Boontheung
Rachel Loo
Samuel A Hasson
Sonya E Neal
Sung-Kun Kim
P2860
P304
P356
10.1091/MBC.E08-10-1062
P577
2009-05-28T00:00:00Z