Structural basis for the requirement of additional factors for MLL1 SET domain activity and recognition of epigenetic marks
about
Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complexThe structure of NSD1 reveals an autoregulatory mechanism underlying histone H3K36 methylationOn the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complexCrystal structure of the human histone methyltransferase ASH1L catalytic domain and its implications for the regulatory mechanismDimerization of a viral SET protein endows its functionStructural and functional coordination of DNA and histone methylationHijacked in cancer: the KMT2 (MLL) family of methyltransferasesOn WD40 proteins: propelling our knowledge of transcriptional control?Regulation of DCC localization by HTZ-1/H2A.Z and DPY-30 does not correlate with H3K4 methylation levelsRole of the polycomb protein EED in the propagation of repressive histone marksStructural Biology of Human H3K9 MethyltransferasesMolecular Mechanism of MLL PHD3 and RNA Recognition by the Cyp33 RRM DomainCharacterization of a Novel WDR5-binding Site That Recruits RbBP5 through a Conserved Motif to Enhance Methylation of Histone H3 Lysine 4 by Mixed Lineage Leukemia Protein-1Structural and biochemical studies of human lysine methyltransferase Smyd3 reveal the important functional roles of its post-SET and TPR domains and the regulation of its activity by DNA bindingLSD2/KDM1B and Its Cofactor NPAC/GLYR1 Endow a Structural and Molecular Model for Regulation of H3K4 DemethylationSymmetric dimethylation of H3R2 is a newly identified histone mark that supports euchromatin maintenanceA novel route to product specificity in the Suv4-20 family of histone H4K20 methyltransferasesStructure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic MutationsModulation of the Chromatin Phosphoproteome by the Haspin Protein KinaseStructural basis for activity regulation of MLL family methyltransferasesSomatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin.Catalytic and functional roles of conserved amino acids in the SET domain of the S. cerevisiae lysine methyltransferase Set1Mutations in Mll2, an H3K4 methyltransferase, result in insulin resistance and impaired glucose tolerance in miceChromatin condensation and recruitment of PHD finger proteins to histone H3K4me3 are mutually exclusiveModulation of epigenetic targets for anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectivesAnthrax SET protein: a potential virulence determinant that epigenetically represses NF-κB activation in infected macrophages.A conserved interaction between the SDI domain of Bre2 and the Dpy-30 domain of Sdc1 is required for histone methylation and gene expression.Haspin: a newly discovered regulator of mitotic chromosome behavior.An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domainA non-active-site SET domain surface crucial for the interaction of MLL1 and the RbBP5/Ash2L heterodimer within MLL family core complexesBioinformatic Identification of Novel MethyltransferasesMixed lineage leukemia: a structure-function perspective of the MLL1 protein.Fluorescence-based methods for screening writers and readers of histone methyl marks.Nuclear role of WASp in the pathogenesis of dysregulated TH1 immunity in human Wiskott-Aldrich syndrome.Substrate and product specificities of SET domain methyltransferasesInner workings and regulatory inputs that control Polycomb repressive complex 2WRAD: enabler of the SET1-family of H3K4 methyltransferases.Keeping it in the family: diverse histone recognition by conserved structural foldsMultifaceted genome control by Set1 Dependent and Independent of H3K4 methylation and the Set1C/COMPASS complex.A novel non-SET domain multi-subunit methyltransferase required for sequential nucleosomal histone H3 methylation by the mixed lineage leukemia protein-1 (MLL1) core complex
P2860
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P2860
Structural basis for the requirement of additional factors for MLL1 SET domain activity and recognition of epigenetic marks
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structural basis for the requi ...... ecognition of epigenetic marks
@ast
Structural basis for the requi ...... ecognition of epigenetic marks
@en
Structural basis for the requi ...... ecognition of epigenetic marks
@en-gb
Structural basis for the requi ...... ecognition of epigenetic marks
@nl
type
label
Structural basis for the requi ...... ecognition of epigenetic marks
@ast
Structural basis for the requi ...... ecognition of epigenetic marks
@en
Structural basis for the requi ...... ecognition of epigenetic marks
@en-gb
Structural basis for the requi ...... ecognition of epigenetic marks
@nl
prefLabel
Structural basis for the requi ...... ecognition of epigenetic marks
@ast
Structural basis for the requi ...... ecognition of epigenetic marks
@en
Structural basis for the requi ...... ecognition of epigenetic marks
@en-gb
Structural basis for the requi ...... ecognition of epigenetic marks
@nl
P2093
P3181
P1433
P1476
Structural basis for the requi ...... ecognition of epigenetic marks
@en
P2093
Poon-Sheng Wong
S Mark Roe
Stacey M Southall
P304
P3181
P356
10.1016/J.MOLCEL.2008.12.029
P407
P50
P577
2009-01-30T00:00:00Z