Cancer cell-autonomous TRAIL-R signaling promotes KRAS-driven cancer progression, invasion, and metastasis
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Onto better TRAILs for cancer treatmentGEMMs as preclinical models for testing pancreatic cancer therapiesThe Janus Face of Death Receptor Signaling during Tumor ImmunoeditingThe linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death.GFI1 downregulation promotes inflammation-linked metastasis of colorectal cancer.Chemotherapy with ceramide in TNBC.Suppression of death receptor 5 enhances cancer cell invasion and metastasis through activation of caspase-8/TRAF2-mediated signaling.Rac1-mediated cytoskeleton rearrangements induced by intersectin-1s deficiency promotes lung cancer cell proliferation, migration and metastasis.Guiding TRAIL to cancer cells through Kv10.1 potassium channel overcomes resistance to doxorubicin.Death receptor 5 (DR5) and a 5-gene apoptotic biomarker panel with significant differential diagnostic potential in colorectal cancer.Potential Role of TRAIL in Metastasis of Mutant KRAS Expressing Lung AdenocarcinomaThe TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2.TRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress.The prognostic relevance of primary tumor location in patients undergoing resection for pancreatic ductal adenocarcinoma.Cell death at the intestinal epithelial front line.Modeling K-Ras-driven lung adenocarcinoma in mice: preclinical validation of therapeutic targets.N-myc downstream-regulated gene 1 promotes oxaliplatin-triggered apoptosis in colorectal cancer cells via enhancing the ubiquitination of Bcl-2.Targeting cell death signalling in cancer: minimising 'Collateral damage'.New insights in the development of pancreatic cancer.Intracellular localization of DR5 and related regulatory pathways as a mechanism of resistance to TRAIL in cancer.Cell death-independent activities of the death receptors CD95, TRAILR1, and TRAILR2.TRAIL-NP hybrids for cancer therapy: a review.NGF sensitizes TrkA SH-SY5Y neuroblastoma cells to TRAIL-induced apoptosis.TRAIL induces pro-apoptotic crosstalk between the TRAIL-receptor signaling pathway and TrkAIII in SH-SY5Y cells, unveiling a potential therapeutic "Achilles heel" for the TrkAIII oncoprotein in neuroblastoma.DR5 suppression induces sphingosine-1-phosphate-dependent TRAF2 polyubiquitination, leading to activation of JNK/AP-1 and promotion of cancer cell invasion.Ubiquitin ligases in oncogenic transformation and cancer therapy.RRS1 silencing suppresses colorectal cancer cell proliferation and tumorigenesis by inhibiting G2/M progression and angiogenesis.YTH domain family 2 orchestrates epithelial-mesenchymal transition/proliferation dichotomy in pancreatic cancer cells.Nanoparticles for Immune Cytokine TRAIL-Based Cancer Therapy.Interaction of reactive astrocytes with type I collagen induces astrocytic scar formation through the integrin-N-cadherin pathway after spinal cord injury.Negative regulators of cell death pathways in cancer: perspective on biomarkers and targeted therapies.Should We Keep Walking along the Trail for Pancreatic Cancer Treatment? Revisiting TNF-Related Apoptosis-Inducing Ligand for Anticancer Therapy.IgG-single-chain TRAIL fusion proteins for tumour therapy.The regulation of combined treatment-induced cell death with recombinant TRAIL and bortezomib through TRAIL signaling in TRAIL-resistant cells.Caspase-independent cell death does not elicit a proliferative response in melanoma cancer cells.
P2860
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P2860
Cancer cell-autonomous TRAIL-R signaling promotes KRAS-driven cancer progression, invasion, and metastasis
description
2015 nî lūn-bûn
@nan
2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Cancer cell-autonomous TRAIL-R ...... sion, invasion, and metastasis
@ast
Cancer cell-autonomous TRAIL-R ...... sion, invasion, and metastasis
@en
Cancer cell-autonomous TRAIL-R ...... sion, invasion, and metastasis
@en-gb
Cancer cell-autonomous TRAIL-R ...... sion, invasion, and metastasis
@nl
type
label
Cancer cell-autonomous TRAIL-R ...... sion, invasion, and metastasis
@ast
Cancer cell-autonomous TRAIL-R ...... sion, invasion, and metastasis
@en
Cancer cell-autonomous TRAIL-R ...... sion, invasion, and metastasis
@en-gb
Cancer cell-autonomous TRAIL-R ...... sion, invasion, and metastasis
@nl
prefLabel
Cancer cell-autonomous TRAIL-R ...... sion, invasion, and metastasis
@ast
Cancer cell-autonomous TRAIL-R ...... sion, invasion, and metastasis
@en
Cancer cell-autonomous TRAIL-R ...... sion, invasion, and metastasis
@en-gb
Cancer cell-autonomous TRAIL-R ...... sion, invasion, and metastasis
@nl
P2093
P50
P3181
P1433
P1476
Cancer cell-autonomous TRAIL-R ...... sion, invasion, and metastasis
@en
P2093
Andrew D Campbell
Anna Trauzold
Annalisa Conti
Anne Grosse-Wilde
Antonella Montinaro
Charlotte Hauser
Frank Bergmann
Franka Annewanter
Holger Kalthoff
Istvan Kenessey
P304
P3181
P356
10.1016/J.CCELL.2015.02.014
P407
P50
P577
2015-04-02T00:00:00Z