STAT3beta, a splice variant of transcription factor STAT3, is a dominant negative regulator of transcription
about
Active Stat3 is required for survival of human squamous cell carcinoma cells in serum-free conditionsPrinciples of interleukin (IL)-6-type cytokine signalling and its regulationInterleukin-6-type cytokine signalling through the gp130/Jak/STAT pathwaySignal transducers and activators of transcription 3 (STAT3) inhibits transcription of the inducible nitric oxide synthase gene by interacting with nuclear factor kappaBMitochondrial Stat3, the Need for Design ThinkingLIF-STAT signaling and trophoblast biologyAltered expression and activation of signal transducers and activators of transcription (STATs) in hepatitis C virus infection: in vivo and in vitro studiesRequirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein.Interferon-resistant Daudi cell line with a Stat2 defect is resistant to apoptosis induced by chemotherapeutic agents.Merging Absolute and Relative Quantitative PCR Data to Quantify STAT3 Splice Variant Transcripts.Caspase-dependent proteolytic cleavage of STAT3alpha in ES cells, in mammary glands undergoing forced involution and in breast cancer cell lines.STAT3 and epithelial-mesenchymal transitions in carcinomasSTAT signaling in the pathogenesis and treatment of cancerRegulation and function of signal transducer and activator of transcription 3.Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteinsLinkage between STAT regulation and Epstein-Barr virus gene expression in tumors.Regulation of hepatic six transmembrane epithelial antigen of prostate 4 (STEAP4) expression by STAT3 and CCAAT/enhancer-binding protein alphaHGF/c-met/Stat3 signaling during skin tumor cell invasion: indications for a positive feedback loop.Rac1 mediates STAT3 activation by autocrine IL-6Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis.High-dose siRNAs upregulate mouse Eri-1 at both transcription and posttranscription levelsHDL and sphingosine-1-phosphate activate stat3 in prostate cancer DU145 cells via ERK1/2 and S1P receptors, and promote cell migration and invasion.Constant splice-isoform ratios in human lymphoblastoid cells support the concept of a splico-statMonoclonal Antibodies Specific for STAT3β Reveal Its Contribution to Constitutive STAT3 Phosphorylation in Breast Cancer.Antitumorigenic potential of STAT3 alternative splicing modulationInhibition of protein phosphatase 2A induces serine/threonine phosphorylation, subcellular redistribution, and functional inhibition of STAT3.Ratios of Four STAT3 Splice Variants in Human Eosinophils and Diffuse Large B Cell Lymphoma CellsRegulation of interleukin 4-mediated signaling by naturally occurring dominant negative and attenuated forms of human Stat6.A genome-wide aberrant RNA splicing in patients with acute myeloid leukemia identifies novel potential disease markers and therapeutic targets.A Key Role for Leukemia Inhibitory Factor in C26 Cancer Cachexia.Signal transducer and activator of transcription (STAT) signalling and T-cell lymphomas.Selective STAT3-α or -β expression reveals spliceform-specific phosphorylation kinetics, nuclear retention and distinct gene expression outcomes.Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines.Human DMTF1β antagonizes DMTF1α regulation of the p14(ARF) tumor suppressor and promotes cellular proliferation.A mix of S and ΔS variants of STAT3 enable survival of activated B-cell-like diffuse large B-cell lymphoma cells in culture.Naturally occurring dominant negative variants of Stat5.Somatic and germline mutation in GRIM-19, a dual function gene involved in mitochondrial metabolism and cell death, is linked to mitochondrion-rich (Hurthle cell) tumours of the thyroid.Ultraviolet radiation and 12-O-tetradecanoylphorbol-13-acetate-induced interaction of mouse epidermal protein kinase Cε with Stat3 involve integration with ERK1/2.LIM-homeodomain transcription factor Isl-1 mediates the effect of leptin on insulin secretion in mice.A novel role of microRNA146b in promoting mammary alveolar progenitor cell maintenance.
P2860
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P2860
STAT3beta, a splice variant of transcription factor STAT3, is a dominant negative regulator of transcription
description
1996 nî lūn-bûn
@nan
1996 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
STAT3beta, a splice variant of ...... ive regulator of transcription
@ast
STAT3beta, a splice variant of ...... ive regulator of transcription
@en
STAT3beta, a splice variant of ...... ive regulator of transcription
@en-gb
STAT3beta, a splice variant of ...... ive regulator of transcription
@nl
type
label
STAT3beta, a splice variant of ...... ive regulator of transcription
@ast
STAT3beta, a splice variant of ...... ive regulator of transcription
@en
STAT3beta, a splice variant of ...... ive regulator of transcription
@en-gb
STAT3beta, a splice variant of ...... ive regulator of transcription
@nl
prefLabel
STAT3beta, a splice variant of ...... ive regulator of transcription
@ast
STAT3beta, a splice variant of ...... ive regulator of transcription
@en
STAT3beta, a splice variant of ...... ive regulator of transcription
@en-gb
STAT3beta, a splice variant of ...... ive regulator of transcription
@nl
P2093
P356
P1476
STAT3beta, a splice variant of ...... ive regulator of transcription
@en
P2093
E Caldenhoven
J A Raaijmakers
J Armstrong
J W Lammers
L Koenderman
R P de Groot
T B van Dijk
P304
13221-13227
P356
10.1074/JBC.271.22.13221
P407
P577
1996-05-01T00:00:00Z