Dysfunctional ryanodine receptors in the heart: new insights into complex cardiovascular diseases
about
Regulation of CaMKII signaling in cardiovascular diseaseGenetic deletion of Rnd3/RhoE results in mouse heart calcium leakage through upregulation of protein kinase A signaling.Patient Specific Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Development and Screening In Catecholaminergic Polymorphic Ventricular TachycardiaAnti-inflammatory drugs for Duchenne muscular dystrophy: focus on skeletal muscle-releasing factorsCaMKII inhibition rectifies arrhythmic phenotype in a patient-specific model of catecholaminergic polymorphic ventricular tachycardia.Cardiac CD47 drives left ventricular heart failure through Ca2+-CaMKII-regulated induction of HDAC3.Calmodulin mutations causing catecholaminergic polymorphic ventricular tachycardia confer opposing functional and biophysical molecular changes.Role of RyR2 phosphorylation in heart failure and arrhythmias: Controversies around ryanodine receptor phosphorylation in cardiac disease.Epac1-dependent phospholamban phosphorylation mediates the cardiac response to stressesRole of RyR2 phosphorylation in heart failure and arrhythmias: protein kinase A-mediated hyperphosphorylation of the ryanodine receptor at serine 2808 does not alter cardiac contractility or cause heart failure and arrhythmiasDisrupted calcium release as a mechanism for atrial alternans associated with human atrial fibrillationInhibition of NAPDH Oxidase 2 (NOX2) Prevents Oxidative Stress and Mitochondrial Abnormalities Caused by Saturated Fat in Cardiomyocytes.Isoproterenol Promotes Rapid Ryanodine Receptor Movement to Bridging Integrator 1 (BIN1)-Organized Dyads.S100A1 DNA-based Inotropic Therapy Protects Against Proarrhythmogenic Ryanodine Receptor 2 Dysfunction.Ryanodine receptor phosphorylation by CaMKII promotes spontaneous Ca(2+) release events in a rodent model of early stage diabetes: The arrhythmogenic substrate.Molecular evidence that exercise training has beneficial effects on cardiac performance.Neuronal Na+ Channels Are Integral Components of Pro-arrhythmic Na+/Ca2+ Signaling Nanodomain That Promotes Cardiac Arrhythmias During β-adrenergic Stimulation.Pleiotropic Effects of Myocardial MMP-9 Inhibition to Prevent Ventricular Arrhythmia.Biodegradable Polymeric Nanocapsules Prevent Cardiotoxicity of Anti-Trypanosomal Lychnopholide.Ryanodine receptors are targeted by anti-apoptotic Bcl-XL involving its BH4 domain and Lys87 from its BH3 domainEmerging pathways driving early synaptic pathology in Alzheimer's disease.Oxidation of RyR2 Has a Biphasic Effect on the Threshold for Store Overload-Induced Calcium Release.Maximal acceleration of Ca2+ release refractoriness by β-adrenergic stimulation requires dual activation of kinases PKA and CaMKII in mouse ventricular myocytes.Dyad content is reduced in cardiac myocytes of mice with impaired calmodulin regulation of RyR2.Mitochondrial oxidative stress promotes atrial fibrillation.Inhibition of NAADP signalling on reperfusion protects the heart by preventing lethal calcium oscillations via two-pore channel 1 and opening of the mitochondrial permeability transition pore.KMUP-1 Attenuates Endothelin-1-Induced Cardiomyocyte Hypertrophy through Activation of Heme Oxygenase-1 and Suppression of the Akt/GSK-3β, Calcineurin/NFATc4 and RhoA/ROCK Pathways.Polycystin-2 Plays an Essential Role in Glucose Starvation-Induced Autophagy in Human Embryonic Stem Cell-Derived Cardiomyocytes.Pivotal role of α2 Na+ pumps and their high affinity ouabain binding site in cardiovascular health and disease.Low-dose exposure of silica nanoparticles induces cardiac dysfunction via neutrophil-mediated inflammation and cardiac contraction in zebrafish embryos.Physiological and unappreciated roles of CaMKII in the heart.
P2860
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P2860
Dysfunctional ryanodine receptors in the heart: new insights into complex cardiovascular diseases
description
2013 nî lūn-bûn
@nan
2013 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Dysfunctional ryanodine recept ...... omplex cardiovascular diseases
@ast
Dysfunctional ryanodine recept ...... omplex cardiovascular diseases
@en
Dysfunctional ryanodine recept ...... omplex cardiovascular diseases
@en-gb
Dysfunctional ryanodine recept ...... omplex cardiovascular diseases
@nl
type
label
Dysfunctional ryanodine recept ...... omplex cardiovascular diseases
@ast
Dysfunctional ryanodine recept ...... omplex cardiovascular diseases
@en
Dysfunctional ryanodine recept ...... omplex cardiovascular diseases
@en-gb
Dysfunctional ryanodine recept ...... omplex cardiovascular diseases
@nl
prefLabel
Dysfunctional ryanodine recept ...... omplex cardiovascular diseases
@ast
Dysfunctional ryanodine recept ...... omplex cardiovascular diseases
@en
Dysfunctional ryanodine recept ...... omplex cardiovascular diseases
@en-gb
Dysfunctional ryanodine recept ...... omplex cardiovascular diseases
@nl
P2860
P921
P3181
P1476
Dysfunctional ryanodine recept ...... omplex cardiovascular diseases
@en
P2093
Andrew R Marks
Steven O Marx
P2860
P304
P3181
P356
10.1016/J.YJMCC.2013.03.005
P407
P577
2013-05-01T00:00:00Z