Role of RyR2 phosphorylation in heart failure and arrhythmias: protein kinase A-mediated hyperphosphorylation of the ryanodine receptor at serine 2808 does not alter cardiac contractility or cause heart failure and arrhythmias

Role of RyR2 phosphorylation in heart failure and arrhythmias: protein kinase A-mediated hyperphosphorylation of the ryanodine receptor at serine 2808 does not alter cardiac contractility or cause heart failure and arrhythmias

Item

http://www.wikidata.org/entity/Q33693920

Q33693920

about

Compartmentalization role of A-kinase anchoring proteins (AKAPs) in mediating protein kinase A (PKA) signaling and cardiomyocyte hypertrophy Dantrolene suppresses spontaneous Ca2+ release without altering excitation-contraction coupling in cardiomyocytes of aged mice.Defects in T-tubular electrical activity underlie local alterations of calcium release in heart failure Muscling in on the ryanodine receptor.Disrupted calcium release as a mechanism for atrial alternans associated with human atrial fibrillation Oxidation of ryanodine receptor (RyR) and calmodulin enhance Ca release and pathologically alter, RyR structure and calmodulin affinity.Isoproterenol Promotes Rapid Ryanodine Receptor Movement to Bridging Integrator 1 (BIN1)-Organized Dyads.mAKAP-a master scaffold for cardiac remodeling.Recent Developments in Heart Failure.Chronic heart failure: Ca(2+), catabolism, and catastrophic cell death.Calcium Signaling and Cardiac Arrhythmias.Ablation of the cardiac ryanodine receptor phospho-site Ser2808 does not alter the adrenergic response or the progression to heart failure in mice. Elimination of the genetic background as critical variable.Endogenous adenosine release is involved in the control of heart rate in rats.Maximal acceleration of Ca2+ release refractoriness by β-adrenergic stimulation requires dual activation of kinases PKA and CaMKII in mouse ventricular myocytes.Dyad content is reduced in cardiac myocytes of mice with impaired calmodulin regulation of RyR2.SPEG (Striated Muscle Preferentially Expressed Protein Kinase) Is Essential for Cardiac Function by Regulating Junctional Membrane Complex Activity.A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway.Age- and strain-related aberrant Ca2+ release is associated with sudden cardiac death in the ACTC E99K mouse model of hypertrophic cardiomyopathy.Force development and intracellular Ca2+ in intact cardiac muscles from gravin mutant mice.Sensitized signalling between L-type Ca2+ channels and ryanodine receptors in the absence or inhibition of FKBP12.6 in cardiomyocytes.Calmodulin kinase II inhibition limits the pro-arrhythmic Ca2+ waves induced by cAMP-phosphodiesterase inhibitors.Calcium in the Pathophysiology of Atrial Fibrillation and Heart Failure The Subcellular Distribution of Ryanodine Receptors and L-Type Ca Channels Modulates Ca-Transient Properties and Spontaneous Ca-Release Events in Atrial Cardiomyocytes

P2860

Q26995781-04B34A11-83EA-44DB-9F6E-D56F31E04FCE Q34201123-2F02297A-1FA2-4F99-867B-F10A17B549D5 Q34409221-48E63B10-FECD-444B-B808-3239223A7FCB Q34461228-2B65B7B7-BEE4-4EE8-A06E-69356AC2D657 Q34679604-DFA92263-DC5A-4BCD-9615-7E681B573901 Q35931379-98F6CD0E-EEAD-4F4D-B126-D59594E79FC9 Q36510338-7D102497-F80D-4809-BA9D-53B7DE9A9B0A Q38304614-BC63D783-C6D0-485A-8622-ED0C1341AE5B Q38584364-40E1AE1B-65FE-4F73-B06E-185AECD3454E Q38699105-397B88CC-0C28-4496-A3E0-CCA3E98EE4F1 Q39360546-C39D3ADF-B97C-4E99-9FAA-B7511F3E83BA Q40390266-D51451F9-412F-471B-BCE2-D478055078AE Q40682600-87828E71-04F7-4505-8904-444924F151EC Q41220738-A661835B-1747-4D7D-B0FA-90FC2790C15A Q41397333-9FEF9B3F-FF60-4874-8371-62771A79B2F2 Q47147382-6F10976C-BC48-4DCF-93E4-69E669449188 Q47567230-F597CE50-603A-4D0B-940F-C125C0DBBC00 Q50194792-CB4CE53D-5414-4736-B407-3BF9FF3B3C7A Q50712920-4D8DAE18-D406-460C-88F0-866B1700B291 Q51198564-9FB05A40-A815-4610-ACA1-642DE2C8F8BF Q54216363-9F616076-C2DB-4188-B3D3-5AA1D67B8005 Q58584159-6328D9E9-BA21-4F86-BDFD-A3F4005F00FA Q58780826-E96E3121-195A-41B8-85FF-48913C1F7112

P2860

Role of RyR2 phosphorylation in heart failure and arrhythmias: protein kinase A-mediated hyperphosphorylation of the ryanodine receptor at serine 2808 does not alter cardiac contractility or cause heart failure and arrhythmias

Item

http://www.wikidata.org/entity/Q33693920

description

2014 nî lūn-bûn

@nan

2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年学术文章

@wuu

2014年学术文章

@zh-cn

2014年学术文章

@zh-hans

2014年学术文章

@zh-my

2014年学术文章

@zh-sg

2014年學術文章

@yue