The cytoplasmic adaptor protein Dok7 activates the receptor tyrosine kinase MuSK via dimerization
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Identification of a Dutch founder mutation in MUSK causing fetal akinesia deformation sequencePathogenesis of myasthenia gravis: update on disease types, models, and mechanismsThe role of muscle-specific tyrosine kinase (MuSK) and mystery of MuSK myasthenia gravisNMR analysis of the IIb 3 cytoplasmic interaction suggests a mechanism for integrin regulationMolecular mechanisms of fibroblast growth factor signaling in physiology and pathologyEffects of the ß2-adrenoceptor agonist, albuterol, in a mouse model of anti-MuSK myasthenia gravisThe downstream of tyrosine kinase 7 is reduced in lung cancer and is associated with poor survival of patients with lung cancerDok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-LA mutation causes MuSK reduced sensitivity to agrin and congenital myasthenia.The MuSK activator agrin has a separate role essential for postnatal maintenance of neuromuscular synapses.Current status of the congenital myasthenic syndromes.Analysis of the Role of the C-Terminal Tail in the Regulation of the Epidermal Growth Factor ReceptorWnt signaling in neuromuscular junction developmentMultiscale Simulations Suggest a Mechanism for the Association of the Dok7 PH Domain with PIP-Containing Membranes.Role of extracellular matrix proteins and their receptors in the development of the vertebrate neuromuscular junctionSorbs1 and -2 Interact with CrkL and Are Required for Acetylcholine Receptor Cluster Formation.DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker.Endosomal trafficking of the receptor tyrosine kinase MuSK proceeds via clathrin-dependent pathways, Arf6 and actin.Structure and activation of MuSK, a receptor tyrosine kinase central to neuromuscular junction formation.Activation of receptor protein-tyrosine kinases from the cytoplasmic compartment.Molecular control of neuromuscular junction developmentStructural mechanisms of the agrin-LRP4-MuSK signaling pathway in neuromuscular junction differentiation.The role of MuSK in synapse formation and neuromuscular disease.Molecular mechanisms of SH2- and PTB-domain-containing proteins in receptor tyrosine kinase signaling.Exploring Missense Mutations in Tyrosine Kinases Implicated with Neurodegeneration.Musk Kinase Activity is Modulated By A Serine Phosphorylation Site in The Kinase LoopSynaptic Homeostasis and Its Immunological Disturbance in Neuromuscular Junction Disorders.The spectrum of mutations that underlie the neuromuscular junction synaptopathy in DOK7 congenital myasthenic syndrome.Salbutamol-responsive limb-girdle congenital myasthenic syndrome due to a novel missense mutation and heteroallelic deletion in MUSK.Muscle Yap Is a Regulator of Neuromuscular Junction Formation and Regeneration.Regulation of chandelier cell cartridge and bouton development via DOCK7-mediated ErbB4 activation.Interaction between ROR1 and MuSK activation complex in myogenic cells.The mouse passive-transfer model of MuSK myasthenia gravis: disrupted MuSK signaling causes synapse failure.Agrin-LRP4-MuSK signaling as a therapeutic target for myasthenia gravis and other neuromuscular disorders.Fundamental Molecules and Mechanisms for Forming and Maintaining Neuromuscular Synapses.The carboxyl-terminal region of Dok-7 plays a key, but not essential, role in activation of muscle-specific receptor kinase MuSK and neuromuscular synapse formation.Muscle-Specific Tyrosine Kinase and Myasthenia Gravis Owing to Other Antibodies.Muscle-specific kinase (MuSK) autoantibodies suppress the MuSK pathway and ACh receptor retention at the mouse neuromuscular junction.Beta-2 Adrenergic Receptor Agonists Enhance AChR Clustering in C2C12 Myotubes: Implications for Therapy of Myasthenic Disorders.
P2860
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P2860
The cytoplasmic adaptor protein Dok7 activates the receptor tyrosine kinase MuSK via dimerization
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The cytoplasmic adaptor protei ...... e kinase MuSK via dimerization
@ast
The cytoplasmic adaptor protei ...... e kinase MuSK via dimerization
@en
The cytoplasmic adaptor protei ...... e kinase MuSK via dimerization
@en-gb
The cytoplasmic adaptor protei ...... e kinase MuSK via dimerization
@nl
type
label
The cytoplasmic adaptor protei ...... e kinase MuSK via dimerization
@ast
The cytoplasmic adaptor protei ...... e kinase MuSK via dimerization
@en
The cytoplasmic adaptor protei ...... e kinase MuSK via dimerization
@en-gb
The cytoplasmic adaptor protei ...... e kinase MuSK via dimerization
@nl
altLabel
The Cytoplasmic Adaptor Protei ...... e Kinase MuSK via Dimerization
@en
prefLabel
The cytoplasmic adaptor protei ...... e kinase MuSK via dimerization
@ast
The cytoplasmic adaptor protei ...... e kinase MuSK via dimerization
@en
The cytoplasmic adaptor protei ...... e kinase MuSK via dimerization
@en-gb
The cytoplasmic adaptor protei ...... e kinase MuSK via dimerization
@nl
P2860
P921
P3181
P1433
P1476
The cytoplasmic adaptor protei ...... e kinase MuSK via dimerization
@en
P2093
Peter T Hallock
Steven J Burden
P2860
P304
P3181
P356
10.1016/J.MOLCEL.2010.06.007
P407
P577
2010-07-01T00:00:00Z