Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis
about
Rho GTPases regulate PRK2/PKN2 to control entry into mitosis and exit from cytokinesis.Crystal structure of triple-BRCT-domain of ECT2 and insights into the binding characteristics to CYK-4KIF14 and citron kinase act together to promote efficient cytokinesisGM130-dependent control of Cdc42 activity at the Golgi regulates centrosome organizationAn ECT2-centralspindlin complex regulates the localization and function of RhoAMgcRacGAP controls the assembly of the contractile ring and the initiation of cytokinesisDissecting the role of Rho-mediated signaling in contractile ring formation.The constitutive centromere component CENP-50 is required for recovery from spindle damage.The Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-SrcAPC(CDH1) targets MgcRacGAP for destruction in the late M phaseCellular contractility requires ubiquitin mediated proteolysisProper regulation of Cdc42 activity is required for tight actin concentration at the equator during cytokinesis in adherent mammalian cellsRac1 is deactivated at integrin activation sites through an IQGAP1-filamin-A-RacGAP1 pathway.A PI3K activity-independent function of p85 regulatory subunit in control of mammalian cytokinesis.mDia2 induces the actin scaffold for the contractile ring and stabilizes its position during cytokinesis in NIH 3T3 cells.The ect2 rho Guanine nucleotide exchange factor is essential for early mouse development and normal cell cytokinesis and migration.Specific deletion of Cdc42 does not affect meiotic spindle organization/migration and homologous chromosome segregation but disrupts polarity establishment and cytokinesis in mouse oocytes.The tumour suppressor DLC2 ensures mitotic fidelity by coordinating spindle positioning and cell-cell adhesionThe guanine nucleotide exchange factor (GEF) Ect2 is an oncogene in human cancer.The small GTPase RhoA localizes to the nucleus and is activated by Net1 and DNA damage signalsThe Rho GTP exchange factor Lfc promotes spindle assembly in early mitosisRho GTPases as regulators of mitosis and cytokinesis in mammalian cells.Understanding cytokinesis failure.Gene expression profiling of chemically induced rat bladder tumors.JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis.Cdc42 and the guanine nucleotide exchange factors Ect2 and trio mediate Fn14-induced migration and invasion of glioblastoma cellsRegulation of the actin cytoskeleton by PIP2 in cytokinesis.The dynamic behavior of Ect2 in response to DNA damage.Polarized Cdc42 activation promotes polar body protrusion and asymmetric division in mouse oocytes.The guanine nucleotide exchange factors trio, Ect2, and Vav3 mediate the invasive behavior of glioblastoma.Rho GTPase-independent regulation of mitotic progression by the RhoGEF Net1The Role of Ect2 Nuclear RhoGEF Activity in Ovarian Cancer Cell Transformation.Activation of the human FP prostanoid receptor disrupts mitosis progression and generates aneuploidy and polyploidy.Rho GTPases modulate malignant transformation of tumor cells.Controlling the switches: Rho GTPase regulation during animal cell mitosis.An essential role of Cdc42-like GTPases in mitosis of HeLa cells.Cell adhesion molecule control of planar spindle orientation.IQGAP1 is a key node within the small GTPase networkQuantitative proteome analysis of pluripotent cells by iTRAQ mass tagging reveals post-transcriptional regulation of proteins required for ES cell self-renewal.Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia.
P2860
Q24298697-F5E5E545-E8CC-4FB6-A465-C52144B05665Q24301484-27EB2B24-72FF-4834-B778-0D18AD69E28DQ24301784-DCAFBCC7-1AF5-4E81-AD7A-4FC9B22EE4E4Q24310719-15A198B0-A98D-48D3-B4F7-FD7564296A5FQ24315633-87C950DF-A2FA-42B0-AFA9-12A3FF1BD95AQ24318853-9DDA4811-3CE9-49B1-8904-A431232D137AQ24338658-E8E8BD1B-F841-430B-8420-3A8492F77810Q24535021-AED606BA-3EDE-4E25-85AB-4EC15C0036F8Q24670372-0DC0B62D-3F06-4860-A160-875CD3009680Q27321457-88194E17-94A8-402E-AAF2-B7EE57E8E638Q27346837-931FA00A-07F5-4C46-BD8E-28749640B675Q28569267-93501CDD-C809-4746-BE72-2F0E6490D3F8Q28680758-B8E0812F-74C7-4F6F-89B7-236B113B22ACQ30478155-536FD786-D2FC-4D78-B6A8-983CB8A7E862Q30481840-637F39AC-5180-40D8-8863-AAC43A59D877Q30515871-474A7AD8-CF48-4870-B193-D79BBEF7F5FFQ30559347-128B405B-0189-46EE-B066-B59641FF3818Q30613021-E84CB8E8-6424-46CB-A637-0F536658FF7FQ33827549-01681BE0-FBEE-4F35-8549-5879C10B8F5FQ33842285-945E17FC-CA28-4C89-A448-A9B5A4E179DBQ33863444-CF6550DD-0B36-4927-A226-0EC5C1D72A48Q34160731-BA84101C-86CE-40D3-BC15-A5F666BE65ABQ34717820-38C9AA22-F025-43F4-B67B-62AD189D373EQ35721181-B8BCB5CC-3578-47FC-B17A-435EA643E02EQ36030193-F46DC4A5-D07E-4DAE-811D-F12DDC7E3D92Q36452209-CB0986C7-2D26-49BF-9A4D-F2050E911F0AQ36480536-C2C43CE6-C822-493E-9435-DFB625437FCDQ36796076-78B835AE-5F2A-424C-A651-334BE66D41D3Q36949359-60B4544E-E55E-4BF7-A9AD-CB68D796EA3FQ37061110-90F471D9-590F-4D66-9264-5E423E81D31EQ37131476-AA03C2D3-571E-44FB-B6F3-23608F668FCAQ37424400-444E1F81-D916-44C4-AA38-4FE975B9DC6EQ37472274-8FCD3C48-2A31-4334-97A2-A44150C007F8Q38230951-C7D674DF-929C-4EE8-A206-99FFDD9F0628Q38257062-FF8989E5-859B-4113-A562-E22440BA8BF3Q38313030-A083A814-05D9-47C3-A8B6-01F60B4C6960Q38677606-7736946C-D286-49CC-8E50-7F438551526CQ39294242-EBC35002-6294-4305-B90A-732DA879513DQ39698217-B5B9B091-CB99-481D-93FB-E9557A63EFF2Q40088786-1C90746D-97F8-43EF-8D5F-018941171AA3
P2860
Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis
@ast
Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis
@en
Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis
@en-gb
Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis
@nl
type
label
Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis
@ast
Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis
@en
Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis
@en-gb
Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis
@nl
prefLabel
Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis
@ast
Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis
@en
Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis
@en-gb
Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis
@nl
P2093
P2860
P921
P3181
P356
P1476
Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis
@en
P2093
Chiharu Higashida
Fabian Oceguera-Yanez
Kazuhiro Kimura
Shingo Yasuda
Shuh Narumiya
Tokuko Haraguchi
Toshio Kitamura
P2860
P304
P3181
P356
10.1083/JCB.200408085
P407
P577
2005-01-17T00:00:00Z