Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression
about
Enhancing tumor-targeting monoclonal antibodies therapy by PARP inhibitorsActivation of the DNA Damage Response by RNA VirusesReaders of poly(ADP-ribose): designed to be fit for purposePARPs and the DNA damage responseThe role of PARP in DNA repair and its therapeutic exploitationStructure and function of the ARH family of ADP-ribosyl-acceptor hydrolasesARTD1 (PARP1) activation and NAD(+) in DNA repair and cell deathThe role of ADP-ribosylation in regulating DNA interstrand crosslink repairTNKS1BP1 functions in DNA double-strand break repair though facilitating DNA-PKcs autophosphorylation dependent on PARP-1PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA.PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways.NuMA promotes homologous recombination repair by regulating the accumulation of the ISWI ATPase SNF2h at DNA breaksPoly(ADP-ribose) polymerase 1 (PARP1) associates with E3 ubiquitin-protein ligase UHRF1 and modulates UHRF1 biological functionsDNA damage related crosstalk between the nucleus and mitochondria.PARP-2 and PARP-3 are selectively activated by 5' phosphorylated DNA breaks through an allosteric regulatory mechanism shared with PARP-1.The role of ADP-ribosylation in regulating DNA double-strand break repairNew facets in the regulation of gene expression by ADP-ribosylation and poly(ADP-ribose) polymerases.Chromatin composition is changed by poly(ADP-ribosyl)ation during chromatin immunoprecipitation.The transcriptional profile of mesenchymal stem cell populations in primary osteoporosis is distinct and shows overexpression of osteogenic inhibitorsAnalysis of poly(ADP-Ribose) polymerases in Arabidopsis telomere biology.The potential for poly (ADP-ribose) polymerase inhibitors in cancer therapy.The clinically active PARP inhibitor AG014699 ameliorates cardiotoxicity but does not enhance the efficacy of doxorubicin, despite improving tumor perfusion and radiation response in mice.Parp3 negatively regulates immunoglobulin class switch recombination.Spontaneous transformation of murine epithelial cells requires the early acquisition of specific chromosomal aneuploidies and genomic imbalances.New PARP targets for cancer therapyA ROS-Activatable Agent Elicits Homologous Recombination DNA Repair and Synergizes with Pathway CompoundsPoly (ADP-ribose) polymerase inhibitors: recent advances and future development.Exploring molecular pathways of triple-negative breast cancerIdentification of differentially expressed genes associated with the enhancement of X-ray susceptibility by RITA in a hypopharyngeal squamous cell carcinoma cell line (FaDu).PARP-2 sustains erythropoiesis in mice by limiting replicative stress in erythroid progenitors.Identification and Functional Characterizations of N-Terminal α-N-Methylation and Phosphorylation of Serine 461 in Human Poly(ADP-ribose) Polymerase 3.PARP-2 domain requirements for DNA damage-dependent activation and localization to sites of DNA damageTherapeutic applications of PARP inhibitors: anticancer therapy and beyondCrosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes.Parp-2 is required to maintain hematopoiesis following sublethal γ-irradiation in miceThe Sound of Silence: RNAi in Poly (ADP-Ribose) ResearchPoly (ADP-ribose) polymerase 3 (PARP3), a potential repressor of telomerase activityPARPs and ADP-ribosylation: recent advances linking molecular functions to biological outcomes.PARP3 controls TGFβ and ROS driven epithelial-to-mesenchymal transition and stemness by stimulating a TG2-Snail-E-cadherin axis.The underlying mechanism for the PARP and BRCA synthetic lethality: clearing up the misunderstandings.
P2860
0210a764bd1eabc36de497ed69bc6b4be24967110f8b6bc657eb1b37895031411cbc4f444ecc00db155df84a8c2eaa4591d1132771e056cc488f6454286a5ba4f066a93621fde9aa46df7d84cfa7e9e42aa4ba3bc9f2fda286a5ed4843917f80be5d840b447113ffa2e80c914a1936c22443b450b37b1b624cca95d78cc0ab11481386d110fcb2c3cae6178f54dc926cf0e14487137abc8c70189517f8d16b23b10e1b2e1cf4e104ee44e1be45e54a79d3a958bae99fe86d07d47786cd94498bd6347c2ca9007e72f63afa884dd7ee3d373ba98b5776508c0c6801b8
P248
Q26768267-6247B95E-5E74-40CA-9101-C09167D7BFF8Q26769967-8BC2032E-9554-40D0-814F-4F5767D5176DQ26775561-B40D7B48-6DDB-416A-A04D-D51C890D1FEDQ26859010-81932FF1-7449-4048-A434-1FE68D84A7A5Q27002399-FFDA1CEB-65B0-4629-873F-74926AED11B5Q27004584-E38ABAA0-F9D3-42B1-9DC1-2F584A421009Q27027461-53F17CF3-759D-446B-8054-9887F4208649Q27727978-BA851884-81D7-4332-A21D-BB820E73531AQ28115068-E68F4D39-FC8F-4971-9684-16E133E0407CQ33629904-28CB6398-96FE-4657-98B1-3AA706398C4AQ33635465-094C6552-2163-4E49-85EE-28D969F56103Q33698675-A09A443D-328E-483D-A412-6E97EFA2A063Q33718499-C074F24D-3772-4BA7-9510-1B3FA8785AB5Q33740063-19694887-20CC-4BEA-8636-90634DC280C6Q33843139-9FB263B6-024E-4B72-84E7-300A9A2715DFQ34029929-A1B9C731-4FB8-4B9B-992B-FF704D6FE455Q34042969-11A40D67-29DC-47BE-97FE-5E3CBDE89A9FQ34221240-FEF69918-1D01-4029-8E0A-686762AF87AFQ34428195-E232D226-9080-47C8-A07A-C15FF27DA363Q35097621-96A7CEBA-FBC6-44A3-88DE-03ADBB3FB305Q35534509-B372A5E0-7EDA-49F0-8E62-26A62A8FA978Q35622211-1D9DCCBE-34D2-4A46-B104-2D203C361DD0Q35637214-85316332-59FB-4F0A-B877-AD5B1F1781FDQ35748478-CD217664-DE53-4F94-8FB5-E3C5612ABF97Q35779661-2BDE9C5E-43A3-45B8-9C32-97970C15E78FQ35792527-44415DA6-BAD8-4529-9EB8-7A8B70E551C1Q35895214-03907D62-9C0F-4A68-B9BB-F7A3252F9CDDQ35959745-095BB2BD-DD5B-45AD-9BDE-5B00665381B6Q36035951-4504AE57-5E69-4536-8790-4C82A4630773Q36056495-B437BE40-9F4C-4A22-A7AA-509423042418Q36436390-355D29B9-3B66-456C-AC84-BDA5C4E7F3D2Q36627921-08076A80-1DB2-4D6D-8B41-2737AC1A20B7Q36853236-8AF66B9F-9A02-44E8-8DD1-A602D18F0054Q36913813-036549F4-D0C0-48FA-9859-106C896378E9Q37032976-A47BF637-BD6D-4820-8E93-DE34700E8308Q37508170-A0A08F90-15E7-4DB7-9500-CA19543D80B3Q37607431-978B78BF-8240-4762-95AB-974867771152Q37661664-EB1AFB38-DF26-41BB-A89D-CA4ED3723A8CQ37665592-8F85E4CD-3FEB-4791-BB33-E4ABA97683F2Q37912812-B5D15D46-B47B-489F-A4A8-5A5073D7E1FB
P2860
Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Poly(ADP-ribose) polymerase 3 ...... damage and mitotic progression
@ast
Poly(ADP-ribose) polymerase 3 ...... damage and mitotic progression
@en
Poly(ADP-ribose) polymerase 3 ...... damage and mitotic progression
@en-gb
Poly(ADP-ribose) polymerase 3 ...... damage and mitotic progression
@nl
type
label
Poly(ADP-ribose) polymerase 3 ...... damage and mitotic progression
@ast
Poly(ADP-ribose) polymerase 3 ...... damage and mitotic progression
@en
Poly(ADP-ribose) polymerase 3 ...... damage and mitotic progression
@en-gb
Poly(ADP-ribose) polymerase 3 ...... damage and mitotic progression
@nl
prefLabel
Poly(ADP-ribose) polymerase 3 ...... damage and mitotic progression
@ast
Poly(ADP-ribose) polymerase 3 ...... damage and mitotic progression
@en
Poly(ADP-ribose) polymerase 3 ...... damage and mitotic progression
@en-gb
Poly(ADP-ribose) polymerase 3 ...... damage and mitotic progression
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
Poly(ADP-ribose) polymerase 3 ...... damage and mitotic progression
@en
P2093
Anne Bresson
Christian Boehler
Denis S Biard
François Boussin
Jean-Michel Saliou
Oliver Mortusewicz
Valérie Schreiber
P2860
P304
P3181
P356
10.1073/PNAS.1016574108
P407
P577
2011-02-15T00:00:00Z