RME-8 coordinates the activity of the WASH complex with the function of the retromer SNX dimer to control endosomal tubulation.
about
J protein mutations and resulting proteostasis collapseGenetic perspective on the role of the autophagy-lysosome pathway in Parkinson diseaseIdentification of molecular heterogeneity in SNX27-retromer-mediated endosome-to-plasma-membrane recyclingCOMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7AThe retromer complex in development and diseaseCCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDLMutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagyA unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer.Nuclear FAM21 participates in NF-κB-dependent gene regulation in pancreatic cancer cells.Rme-8 depletion perturbs Notch recycling and predisposes to pathogenic signaling.ALIX Regulates the Ubiquitin-Independent Lysosomal Sorting of the P2Y1 Purinergic Receptor via a YPX3L Motif.Endosomal sorting of Notch receptors through COMMD9-dependent pathways modulates Notch signaling.A defect in the retromer accessory protein, SNX27, manifests by infantile myoclonic epilepsy and neurodegeneration.Atypical parkinsonism-associated retromer mutant alters endosomal sorting of specific cargo proteins.SNX-1 and RME-8 oppose the assembly of HGRS-1/ESCRT-0 degradative microdomains on endosomesRetromer-mediated endosomal protein sorting: The role of unstructured domains.Retromer-Mediated Trafficking of Transmembrane Receptors and Transporters.Endocytic membrane trafficking and neurodegenerative disease.The emerging role of retromer in neuroprotection.TMEM230: How does it fit in the etiology and pathogenesis of Parkinson's disease?The Role of Co-chaperones in Synaptic Proteostasis and Neurodegenerative Disease.Loss of strumpellin in the melanocytic lineage impairs the WASH Complex but does not affect coat colour.Analysis of the Retromer complex-WASH complex interaction illuminates new avenues to explore in Parkinson disease.The functional roles of retromer in Parkinson's disease.Retromer and the cation-independent mannose 6-phosphate receptor-Time for a trial separation?Sequence-dependent cargo recognition by SNX-BARs mediates retromer-independent transport of CI-MPR.Cargo-selective SNX-BAR proteins mediate retromer trimer independent retrograde transport.Retromer-dependent neurotransmitter receptor trafficking to synapses is altered by the Parkinson's disease VPS35 mutation p.D620N.DnaJ/Hsp40 Family and Parkinson's Disease.Endosomal Receptor Trafficking: Retromer and Beyond.
P2860
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P2860
RME-8 coordinates the activity of the WASH complex with the function of the retromer SNX dimer to control endosomal tubulation.
description
2014 nî lūn-bûn
@nan
2014 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մարտին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
RME-8 coordinates the activity ...... o control endosomal tubulation
@nl
RME-8 coordinates the activity ...... control endosomal tubulation.
@ast
RME-8 coordinates the activity ...... control endosomal tubulation.
@en
RME-8 coordinates the activity ...... control endosomal tubulation.
@en-gb
type
label
RME-8 coordinates the activity ...... o control endosomal tubulation
@nl
RME-8 coordinates the activity ...... control endosomal tubulation.
@ast
RME-8 coordinates the activity ...... control endosomal tubulation.
@en
RME-8 coordinates the activity ...... control endosomal tubulation.
@en-gb
prefLabel
RME-8 coordinates the activity ...... o control endosomal tubulation
@nl
RME-8 coordinates the activity ...... control endosomal tubulation.
@ast
RME-8 coordinates the activity ...... control endosomal tubulation.
@en
RME-8 coordinates the activity ...... control endosomal tubulation.
@en-gb
P2093
P2860
P3181
P356
P1476
RME-8 coordinates the activity ...... control endosomal tubulation.
@en
P2093
Caroline L Freeman
Geoffrey Hesketh
Matthew N J Seaman
P2860
P304
P3181
P356
10.1242/JCS.144659
P407
P577
2014-03-18T00:00:00Z