SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors.
about
VARP is recruited on to endosomes by direct interaction with retromer, where together they function in export to the cell surfaceIdentification of molecular heterogeneity in SNX27-retromer-mediated endosome-to-plasma-membrane recyclingEndosomal recruitment of the WASH complex: active sequences and mutations impairing interaction with the retromerEndosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia.A mechanism for retromer endosomal coat complex assembly with cargoStructural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteinsA global analysis of SNX27-retromer assembly and cargo specificity reveals a function in glucose and metal ion transportRME-8 coordinates the activity of the WASH complex with the function of the retromer SNX dimer to control endosomal tubulation.LTP requires a unique postsynaptic SNARE fusion machineryRole of the Retromer Complex in Neurodegenerative DiseasesThe retromer complex in development and diseaseClass III phosphatidylinositol 3-kinase and its catalytic product PtdIns3P in regulation of endocytic membrane trafficThe retromer complex - endosomal protein recycling and beyondEndocytic trafficking of chemokine receptorsFunction and regulation of the endosomal fusion and fission machineriesSorting through the roles of beclin 1 in microglia and neurodegenerationOCRL1 engages with the F-BAR protein pacsin 2 to promote biogenesis of membrane-trafficking intermediates.ARF6-JIP3/4 regulate endosomal tubules for MT1-MMP exocytosis in cancer invasion.Intracellular Transport of Vaccinia Virus in HeLa Cells Requires WASH-VPEF/FAM21-Retromer Complexes and Recycling Molecules Rab11 and Rab22.Phosphoinositide binding by the SNX27 FERM domain regulates its localization at the immune synapse of activated T-cells.Biogenesis of endosome-derived transport carriers.A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complexTwo novel WD40 domain-containing proteins, Ere1 and Ere2, function in the retromer-mediated endosomal recycling pathway.Parkinson Disease-linked Vps35 R524W Mutation Impairs the Endosomal Association of Retromer and Induces α-Synuclein AggregationRetromer Ensures the Degradation of Autophagic Cargo by Maintaining Lysosome Function in DrosophilaVPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for α-Synuclein Degradation and Prevention of Pathogenesis of Parkinson's DiseaseRetromer-mediated endosomal protein sorting: all WASHed up!Sorting nexin 27 interacts with multidrug resistance-associated protein 4 (MRP4) and mediates internalization of MRP4Dendritic cells utilize the evolutionarily conserved WASH and retromer complexes to promote MHCII recycling and helper T cell primingWASH knockout T cells demonstrate defective receptor trafficking, proliferation, and effector functionIdentification of VHY/Dusp15 as a regulator of oligodendrocyte differentiation through a systematic genomics approachCCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDLEffects of the β-agonist, isoprenaline, on the down-regulation, functional responsiveness and trafficking of β2-adrenergic receptors with N-terminal polymorphisms.Rab9 and retromer regulate retrograde trafficking of luminal protein required for epithelial tube length control.Regulation of integrin trafficking, cell adhesion, and cell migration by WASH and the Arp2/3 complexNormal dynactin complex function during synapse growth in Drosophila requires membrane binding by ArfaptinAn ESCRT-spastin interaction promotes fission of recycling tubules from the endosome.Reprogramming of G protein-coupled receptor recycling and signaling by a kinase switch.A role for sorting nexin 27 in AMPA receptor trafficking.Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy
P2860
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P2860
SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
SNX27 mediates retromer tubule ...... icking of signalling receptors
@nl
SNX27 mediates retromer tubule ...... cking of signalling receptors.
@ast
SNX27 mediates retromer tubule ...... cking of signalling receptors.
@en
SNX27 mediates retromer tubule ...... cking of signalling receptors.
@en-gb
type
label
SNX27 mediates retromer tubule ...... icking of signalling receptors
@nl
SNX27 mediates retromer tubule ...... cking of signalling receptors.
@ast
SNX27 mediates retromer tubule ...... cking of signalling receptors.
@en
SNX27 mediates retromer tubule ...... cking of signalling receptors.
@en-gb
prefLabel
SNX27 mediates retromer tubule ...... icking of signalling receptors
@nl
SNX27 mediates retromer tubule ...... cking of signalling receptors.
@ast
SNX27 mediates retromer tubule ...... cking of signalling receptors.
@en
SNX27 mediates retromer tubule ...... cking of signalling receptors.
@en-gb
P2093
P2860
P921
P3181
P356
P1433
P1476
SNX27 mediates retromer tubule ...... cking of signalling receptors.
@en
P2093
Ben Lauffer
Nevan J Krogan
Paul Temkin
Peter Cimermancic
Stefanie Jäger
P2860
P2888
P304
P3181
P356
10.1038/NCB2252
P407
P577
2011-05-22T00:00:00Z
P5875
P6179
1019202755