Differential effects of Rad52p overexpression on gene targeting and extrachromosomal homologous recombination in a human cell line
about
Potentiation of gene targeting in human cells by expression of Saccharomyces cerevisiae Rad52Oligo/polynucleotide-based gene modification: strategies and therapeutic potentialStringent and reproducible tetracycline-regulated transgene expression by site-specific insertion at chromosomal loci with pre-characterised induction characteristics.RAD51 paralogs promote homology-directed repair at diversifying immunoglobulin V regionsHuman Rad52 binds and wraps single-stranded DNA and mediates annealing via two hRad52-ssDNA complexes.Targeted mutagenesis by homologous recombination in D. melanogaster.BCCIP regulates homologous recombination by distinct domains and suppresses spontaneous DNA damage.High levels of RAD51 perturb DNA replication elongation and cause unscheduled origin firing due to impaired CHK1 activation.Small-molecule inhibitors identify the RAD52-ssDNA interaction as critical for recovery from replication stress and for survival of BRCA2 deficient cellsGene modulation associated with inhibition of liver regeneration in hepatitis B virus X transgenic miceDiscriminatory suppression of homologous recombination by p53.Enhancement of extra chromosomal recombination in somatic cells by affecting the ratio of homologous recombination (HR) to non-homologous end joining (NHEJ).Sequence-specific correction of genomic hypoxanthine-guanine phosphoribosyl transferase mutations in lymphoblasts by small fragment homologous replacement.Enhancement of gene targeting in human cells by intranuclear permeation of the Saccharomyces cerevisiae Rad52 proteinIdentification of genes regulating gene targeting by a high-throughput screening approach.Small-Molecule Inhibitors Targeting DNA Repair and DNA Repair Deficiency in Research and Cancer Therapy.Herpes ICP8 protein stimulates homologous recombination in human cells
P2860
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P2860
Differential effects of Rad52p overexpression on gene targeting and extrachromosomal homologous recombination in a human cell line
description
2002 nî lūn-bûn
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2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2002 թվականի փետրվարին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年论文
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name
Differential effects of Rad52p ...... mbination in a human cell line
@ast
Differential effects of Rad52p ...... mbination in a human cell line
@en
Differential effects of Rad52p ...... mbination in a human cell line
@en-gb
Differential effects of Rad52p ...... mbination in a human cell line
@nl
type
label
Differential effects of Rad52p ...... mbination in a human cell line
@ast
Differential effects of Rad52p ...... mbination in a human cell line
@en
Differential effects of Rad52p ...... mbination in a human cell line
@en-gb
Differential effects of Rad52p ...... mbination in a human cell line
@nl
prefLabel
Differential effects of Rad52p ...... mbination in a human cell line
@ast
Differential effects of Rad52p ...... mbination in a human cell line
@en
Differential effects of Rad52p ...... mbination in a human cell line
@en-gb
Differential effects of Rad52p ...... mbination in a human cell line
@nl
P2860
P3181
P356
P1476
Differential effects of Rad52p ...... mbination in a human cell line
@en
P2093
Andrew C G Porter
Rafael J Yáñez
P2860
P3181
P356
10.1093/NAR/30.3.740
P407
P577
2002-02-01T00:00:00Z