Cloning of human and mouse genes homologous to RAD52, a yeast gene involved in DNA repair and recombination
about
The XRCC2 DNA repair gene from human and mouse encodes a novel member of the recA/RAD51 familyDifferential effects of Rad52p overexpression on gene targeting and extrachromosomal homologous recombination in a human cell lineChromosomal double-strand break repair in Ku80-deficient cellsRad52 forms ring structures and co-operates with RPA in single-strand DNA annealing.Human and yeast Rad52 proteins promote DNA strand exchange.Roles of C-Terminal Region of Yeast and Human Rad52 in Rad51-Nucleoprotein Filament Formation and ssDNA AnnealingStimulation by Rad52 of yeast Rad51-mediated recombinationExpression of human RAD52 confers resistance to ionizing radiation in mammalian cellsRad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell deathDNA IR-Double Strand Breaks (DSBs) and cellular response via ATMDNA annealing by RAD52 protein is stimulated by specific interaction with the complex of replication protein A and single-stranded DNAHuman Rad52 binds and wraps single-stranded DNA and mediates annealing via two hRad52-ssDNA complexes.Rad51 inhibits translocation formation by non-conservative homologous recombination in Saccharomyces cerevisiae.Targeted inactivation of mouse RAD52 reduces homologous recombination but not resistance to ionizing radiation.Recombinational repair in yeast: functional interactions between Rad51 and Rad54 proteins.Immunodeficiency associated with DNA repair defects.Conservative repair of a chromosomal double-strand break by single-strand DNA through two steps of annealing.Human RAD52 interactions with replication protein A and the RAD51 presynaptic complex.The Drosophila melanogaster RAD54 homolog, DmRAD54, is involved in the repair of radiation damage and recombination.Detection of loss of heterozygosity at RAD51, RAD52, RAD54 and BRCA1 and BRCA2 loci in breast cancer: pathological correlations.DNA strand annealing is promoted by the yeast Rad52 protein.Role of the Rad52 amino-terminal DNA binding activity in DNA strand capture in homologous recombination.DNA-PK, the DNA-activated protein kinase, is differentially expressed in normal and malignant human tissues.Gene conversion plays the major role in controlling the stability of large tandem repeats in yeastPersonalised Medicine: Genome Maintenance Lessons Learned from Studies in Yeast as a Model Organism.A double-strand break repair component is essential for S phase completion in fission yeast cell cycling.Homologous and nonhomologous recombination resulting in deletion: effects of p53 status, microhomology, and repetitive DNA length and orientation.Homologous recombination, but not DNA repair, is reduced in vertebrate cells deficient in RAD52.Xrcc2 is required for genetic stability, embryonic neurogenesis and viability in miceCoordinated response of mammalian Rad51 and Rad52 to DNA damage.Cellular resistance to camptothecins.On the role of DNA double-strand breaks in toxicity and carcinogenesis.The Saccharomyces cerevisiae Ku autoantigen homologue affects radiosensitivity only in the absence of homologous recombination.The N-terminal DNA-binding domain of Rad52 promotes RAD51-independent recombination in Saccharomyces cerevisiae.Elevated levels of homologous DNA recombination activity in the regenerating rat liver.Multiple start codons and phosphorylation result in discrete Rad52 protein species.A molecular genetic dissection of the evolutionarily conserved N terminus of yeast Rad52.The DNA binding preference of RAD52 and RAD59 proteins: implications for RAD52 and RAD59 protein function in homologous recombination.Homologous pairing promoted by the human Rad52 protein.Synergistic actions of Rad51 and Rad52 in recombination and DNA repair.
P2860
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P2860
Cloning of human and mouse genes homologous to RAD52, a yeast gene involved in DNA repair and recombination
description
1994 nî lūn-bûn
@nan
1994 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Cloning of human and mouse gen ...... n DNA repair and recombination
@ast
Cloning of human and mouse gen ...... n DNA repair and recombination
@en
Cloning of human and mouse gen ...... n DNA repair and recombination
@nl
type
label
Cloning of human and mouse gen ...... n DNA repair and recombination
@ast
Cloning of human and mouse gen ...... n DNA repair and recombination
@en
Cloning of human and mouse gen ...... n DNA repair and recombination
@nl
prefLabel
Cloning of human and mouse gen ...... n DNA repair and recombination
@ast
Cloning of human and mouse gen ...... n DNA repair and recombination
@en
Cloning of human and mouse gen ...... n DNA repair and recombination
@nl
P2093
P3181
P1433
P1476
Cloning of human and mouse gen ...... n DNA repair and recombination
@en
P2093
A S Balajee
C J Osgood
C Troelstra
J H Hoeijmakers
J M Buerstedde
K Ostermann
O Bezzubova
P304
P3181
P356
10.1016/0921-8777(94)90040-X
P407
P577
1994-11-01T00:00:00Z