Chromosomal clustering of genes controlled by the aire transcription factor.
about
Aire and T cell developmentTranscriptional regulation by AIRE: molecular mechanisms of central toleranceOvarian autoimmune disease: clinical concepts and animal modelsThe solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylationCentral tolerance: learning self-control in the thymusAnti-interferon autoantibodies in autoimmune polyendocrinopathy syndrome type 1Regulation of T-cell Tolerance by Lymphatic Endothelial Cells.OrthoClusterDB: an online platform for synteny blocks.Control of central and peripheral tolerance by Aire.Epigenetic regulation of promiscuous gene expression in thymic medullary epithelial cells.APECED: A Paradigm of Complex Interactions between Genetic Background and Susceptibility FactorsClues to immune tolerance: the monogenic autoimmune syndromesDNA methylation profile of Aire-deficient mouse medullary thymic epithelial cellsA functional alternative splicing mutation in AIRE gene causes autoimmune polyendocrine syndrome type 1.Overexpression of the IGF2-mRNA binding protein p62 in transgenic mice induces a steatotic phenotype.Insulin transactivator MafA regulates intrathymic expression of insulin and affects susceptibility to type 1 diabetes.Unmodified histone H3K4 and DNA-dependent protein kinase recruit autoimmune regulator to target genes.Brd4 bridges the transcriptional regulators, Aire and P-TEFb, to promote elongation of peripheral-tissue antigen transcripts in thymic stromal cellsAire controls gene expression in the thymic epithelium with ordered stochasticityImmunity by ubiquitylation: a reversible process of modification.Single-cell transcriptome analysis reveals coordinated ectopic gene-expression patterns in medullary thymic epithelial cellsModifier loci condition autoimmunity provoked by Aire deficiency.Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire.Tissue-targeted therapy of autoimmune diabetes using dendritic cells transduced to express IL-4 in NOD miceTranscriptional impact of Aire varies with cell type.Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity.Ectopic expression of peripheral-tissue antigens in the thymic epithelium: probabilistic, monoallelic, misinitiatedOverlapping gene coexpression patterns in human medullary thymic epithelial cells generate self-antigen diversity.Critical immunological pathways are downregulated in APECED patient dendritic cells.Expression profile of a clonal insulin-expressing epithelial cell in the thymus.CD28- and CD28lowCD8+ Regulatory T Cells: Of Mice and MenAIRE in the thymus and beyond.The role of Aire in clonal selection.Expression and function of the autoimmune regulator (Aire) gene in non-thymic tissue.Genetic basis of altered central tolerance and autoimmune diseases: a lesson from AIRE mutations.Alterations of the autoimmune regulator transcription factor and failure of central tolerance: APECED as a model.Regulations of gene expression in medullary thymic epithelial cells required for preventing the onset of autoimmune diseases.Autoimmune Regulator (AIRE) Is Expressed in Spermatogenic Cells, and It Altered the Expression of Several Nucleic-Acid-Binding and Cytoskeletal Proteins in Germ Cell 1 Spermatogonial (GC1-spg) Cells.Spatial mapping of thymic stromal microenvironments reveals unique features influencing T lymphoid differentiation.AIRE: From promiscuous molecular partnerships to promiscuous gene expression.
P2860
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P2860
Chromosomal clustering of genes controlled by the aire transcription factor.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Chromosomal clustering of genes controlled by the aire transcription factor
@nl
Chromosomal clustering of genes controlled by the aire transcription factor.
@ast
Chromosomal clustering of genes controlled by the aire transcription factor.
@en
Chromosomal clustering of genes controlled by the aire transcription factor.
@en-gb
type
label
Chromosomal clustering of genes controlled by the aire transcription factor
@nl
Chromosomal clustering of genes controlled by the aire transcription factor.
@ast
Chromosomal clustering of genes controlled by the aire transcription factor.
@en
Chromosomal clustering of genes controlled by the aire transcription factor.
@en-gb
prefLabel
Chromosomal clustering of genes controlled by the aire transcription factor
@nl
Chromosomal clustering of genes controlled by the aire transcription factor.
@ast
Chromosomal clustering of genes controlled by the aire transcription factor.
@en
Chromosomal clustering of genes controlled by the aire transcription factor.
@en-gb
P2093
P2860
P356
P1476
Chromosomal clustering of genes controlled by the aire transcription factor.
@en
P2093
Christophe O Benoist
Debra J Taxman
Diane J Mathis
Emily S Venanzi
Jenny P-Y Ting
Jonathan B Johnnidis
P2860
P304
P356
10.1073/PNAS.0502670102
P407
P577
2005-05-09T00:00:00Z