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Post-Aire Maturation of Thymic Medullary Epithelial Cells Involves Selective Expression of Keratinocyte-Specific AutoantigensThymic and Postthymic Regulation of Naïve CD4(+) T-Cell Lineage Fates in Humans and Mice ModelsT Cells: Soldiers and Spies--The Surveillance and Control of Effector T Cells by Regulatory T CellsBeyond DNA repair: DNA-PK function in cancerNewly recognized Mendelian disorders with rheumatic manifestationsUbiquitin in the immune systemSolving the puzzle of autoimmunity: critical questionsNFKB2 mutation in common variable immunodeficiency and isolated adrenocorticotropic hormone deficiency: A case report and review of literatureB-Raf is required for positive selection and survival of DP cells, but not for negative selection of SP cellsRestoring the balance: immunotherapeutic combinations for autoimmune diseaseSex bias in CNS autoimmune disease mediated by androgen control of autoimmune regulator.Rag defects and thymic stroma: lessons from animal models.Compensatory mechanisms allow undersized anchor-deficient class I MHC ligands to mediate pathogenic autoreactive T cell responsesDistinct contributions of Aire and antigen-presenting-cell subsets to the generation of self-tolerance in the thymusNegative selection assay based on stimulation of T cell receptor transgenic thymocytes with peptide-MHC tetramersNormal T cell selection occurs in CD205-deficient thymic microenvironments.Homeostatic properties and phenotypic maturation of murine CD4+ pre-thymic emigrants in the thymus.Impaired thymic expression of tissue-restricted antigens licenses the de novo generation of autoreactive CD4+ T cells in acute GVHD.Thymic involution perturbs negative selection leading to autoreactive T cells that induce chronic inflammation.PRKDC mutations associated with immunodeficiency, granuloma, and autoimmune regulator-dependent autoimmunity.T cells in the control of organ-specific autoimmunityUnmodified histone H3K4 and DNA-dependent protein kinase recruit autoimmune regulator to target genes.Intercellular Protein Transfer from Thymocytes to Thymic Epithelial CellsDetection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection.Sequence variation in promoter of Ica1 gene, which encodes protein implicated in type 1 diabetes, causes transcription factor autoimmune regulator (AIRE) to increase its binding and down-regulate expression.Paracoccidioides brasiliensis infection promotes thymic disarrangement and premature egress of mature lymphocytes expressing prohibitive TCRsAge-Related Disruption of Steady-State Thymic Medulla Provokes Autoimmune Phenotype via Perturbing Negative Selection.Mechanistic basis of immunotherapies for type 1 diabetes mellitusThe heart of the matter: protection of the myocardium from T cellsLYN- and AIRE-mediated tolerance checkpoint defects synergize to trigger organ-specific autoimmunity.Protein microarray analysis reveals BAFF-binding autoantibodies in systemic lupus erythematosus.Aire Downregulation Is Associated with Changes in the Posttranscriptional Control of Peripheral Tissue Antigens in Medullary Thymic Epithelial Cells.From pre-DP, post-DP, SP4, and SP8 Thymocyte Cell Counts to a Dynamical Model of Cortical and Medullary Selection.Treatment of Pediatric Acute Graft-versus-Host Disease-Lessons from Primary Immunodeficiency?Mucocutaneous candidiasis and autoimmunity against cytokines in APECED and thymoma patients: clinical and pathogenetic implications.Immune tolerance and autoimmune uveoretinitis: the role of the ocular microenvironment.Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy: known and novel aspects of the syndrome.Pleiotropic targets: the problem of shared signaling circuitry in rheumatoid arthritis disease progression and protection.Overlooked non-motor symptoms in myasthenia gravis.Thymic regulatory T cell development: role of signalling pathways and transcription factors.
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Aire and T cell development
@ast
Aire and T cell development
@en
Aire and T cell development
@nl
type
label
Aire and T cell development
@ast
Aire and T cell development
@en
Aire and T cell development
@nl
prefLabel
Aire and T cell development
@ast
Aire and T cell development
@en
Aire and T cell development
@nl
P2860
P3181
P1476
Aire and T cell development
@en
P2093
Mark S Anderson
P2860
P304
P3181
P356
10.1016/J.COI.2010.11.007
P407
P50
P577
2010-12-14T00:00:00Z