Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300.
about
Expression of DDX3 is directly modulated by hypoxia inducible factor-1 alpha in breast epithelial cellsCloning and expression analysis of two distinct HIF-alpha isoforms--gcHIF-1alpha and gcHIF-4alpha--from the hypoxia-tolerant grass carp, Ctenopharyngodon idellusFIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activityFIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factorModulation of p300 binding by posttranslational modifications of the C-terminal activation domain of hypoxia-inducible factor-1alphaLoss of Mel-18 induces tumor angiogenesis through enhancing the activity and expression of HIF-1α mediated by the PTEN/PI3K/Akt pathwayAnalysis of nuclear transport signals in the human apurinic/apyrimidinic endonuclease (APE1/Ref1).USF1 and USF2 mediate inhibition of human trophoblast differentiation and CYP19 gene expression by Mash-2 and hypoxiaSENP3 is responsible for HIF-1 transactivation under mild oxidative stress via p300 de-SUMOylationStructural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alphaConditional knockout mice reveal distinct functions for the global transcriptional coactivators CBP and p300 in T-cell developmentStructure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway.Redox-regulated recruitment of the transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1alphaMechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor proteinThe possible mechanisms underlying the impairment of HIF-1α pathway signaling in hyperglycemia and the beneficial effects of certain therapiesHypoxia upregulates the expression of the NDRG1 gene leading to its overexpression in various human cancersOxygen-sensing mechanisms and the regulation of redox-responsive transcription factors in development and pathophysiologyTargeting Protein-Protein Interactions in the HIF SystemCurrent insights into the molecular mechanisms of hypoxic pre- and postconditioning using hypobaric hypoxiaThe hypoxia-inducible factor pathway, prolyl hydroxylase domain protein inhibitors, and their roles in bone repair and regenerationHuman AP endonuclease 1: a potential marker for the prediction of environmental carcinogenesis riskHydrogen peroxide sensing, signaling and regulation of transcription factorsStructural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response.Evolution of the redox function in mammalian apurinic/apyrimidinic endonucleaseRedox modification of proteins as essential mediators of CNS autophagy and mitophagy.Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylationCarboxyl-terminal transactivation activity of hypoxia-inducible factor 1 alpha is governed by a von Hippel-Lindau protein-independent, hydroxylation-regulated association with p300/CBP.Discovery and optimization of small-molecule ligands for the CBP/p300 bromodomainsNegative regulation of hypoxia inducible factor-1alpha by necdinSumoylation of hypoxia-inducible factor-1α ameliorates failure of brain stem cardiovascular regulation in experimental brain deathPro-apoptotic activity of inhibitory PAS domain protein (IPAS), a negative regulator of HIF-1, through binding to pro-survival Bcl-2 family proteinsHypoxia-inducible factor 2alpha regulates expression of the mitochondrial aconitase chaperone protein frataxinDefective development of secretory neurones in the hypothalamus of Arnt2-knockout miceDefective brain development in mice lacking the Hif-1alpha gene in neural cellsGlucose down-regulates Per1 and Per2 mRNA levels and induces circadian gene expression in cultured Rat-1 fibroblastsHypoxia-activated metabolic pathway stimulates phosphorylation of p300 and CBP in oxygen-sensitive cellsA novel transactivating factor that regulates interferon-gamma-dependent gene expressionRepression of gene expression by oxidative stressDifferential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulationHIF hydroxylation and cellular oxygen sensing.
P2860
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P2860
Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300.
description
1999 nî lūn-bûn
@nan
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
Molecular mechanisms of transc ...... uced interaction with CBP/p300
@nl
Molecular mechanisms of transc ...... ced interaction with CBP/p300.
@ast
Molecular mechanisms of transc ...... ced interaction with CBP/p300.
@en
Molecular mechanisms of transc ...... ced interaction with CBP/p300.
@en-gb
type
label
Molecular mechanisms of transc ...... uced interaction with CBP/p300
@nl
Molecular mechanisms of transc ...... ced interaction with CBP/p300.
@ast
Molecular mechanisms of transc ...... ced interaction with CBP/p300.
@en
Molecular mechanisms of transc ...... ced interaction with CBP/p300.
@en-gb
prefLabel
Molecular mechanisms of transc ...... uced interaction with CBP/p300
@nl
Molecular mechanisms of transc ...... ced interaction with CBP/p300.
@ast
Molecular mechanisms of transc ...... ced interaction with CBP/p300.
@en
Molecular mechanisms of transc ...... ced interaction with CBP/p300.
@en-gb
P2093
P2860
P356
P1433
P1476
Molecular mechanisms of transc ...... ced interaction with CBP/p300.
@en
P2093
Fujii-Kuriyama Y
Poellinger L
P2860
P304
P356
10.1093/EMBOJ/18.7.1905
P407
P577
1999-04-01T00:00:00Z